Abstract: Provided are a three-dimensional carbon-based copolymerization composite, and a preparation method and use thereof.

Abstract: Provided is an oral Pt(IV) anticancer prodrug containing a 3-bromopyruvate as an axial ligand, with a molecular formula of cis,trans,cis-[Pt(1R,2R-diaminocyclohexane)(OH)(3-bromopyruvate)(C2O4)]. It is a prodrug of oxaliplatin and 3-bromopyruvic acid is a small molecular glycolysis inhibitor. The prodrug is able to simultaneously act on DNA replication and glycolytic pathways of cancer cells, giving full play to the advantage of double-acting targets. The oral Pt(IV) anticancer prodrug is synthesized by using oxaliplatin as a starting material, performing axial oxidation with H2O2 and neutralizing the oxidized product with 3-bromopyruvic acid.

Abstract: Provided are a water-soluble Pd(II) complex, a synthesis method thereof and use thereof as a catalytic precursor. The complex has a chemical name, ammonium dinitrooxalato palladium (II), and a molecular formula of (NH4)2[Pd(NO2)2(C2O4)]·nH2O (n is the number of crystal water). The Pd(II) complex is synthesized by using PdCl2 or [Pd(NH3)2Cl2] as a starting material which is firstly converted into [Pd(NH3)4]Cl2 in ammonium hydroxide, followed by a chemical reaction between [Pd(NH3)4]Cl2 and excessive NaNO2 to produce trans-[Pd(NH3)2(NO2)2] via ligand substitution mechanism, and finally dissolving trans-[Pd(NH3)2(NO2)2] in an aqueous solution of oxalic acid leads to the formation of the target product (NH4)2[Pd(NO2)2(C2O4)]·2H2O. The complex does not contain chlorine and other elements that are harmful to a catalyst, is readily soluble in water and has a low thermal decomposition temperature.

Abstract: The present disclosure relates to the field of lighting adjustment technologies, and in particular to a lighting adjustment system and method. The system includes: a light sensor, a personnel controller, a central processing unit, and a lighting device, where the light sensor, the personnel controller, and the lighting device are all wirelessly connected to the central processing unit; the light sensor is arranged at a preset monitoring point, and configured to receive monitoring information at the monitoring point; the personnel controller is configured to obtain a lighting environment creation selection of control personnel; the central processing unit is configured to regulate beam angle, color temperature, and illuminance of the lighting device in real time based on the received monitoring information and the lighting environment creation selection; and the lighting device is arranged at the monitoring point preset indoors.

Abstract: Provided are a compound as represented by formula I, a preparation method therefor, and a hydrochloride crystal form A thereof. The compound as represented by formula I and the hydrochloride crystal form A thereof have excellent inhibitory effects on transient receptor potential (TRP) channels, and have good therapeutic effects on TRP channel-associated diseases.

Abstract: The present invention discloses a unit commitment method considering security region of wind turbine generators with frequency response control, and the main steps are: 1) determining security region of wind turbine generators when provides frequency response; 2) based on the security region of the wind turbine generators when provides frequency response, establishing a unit commitment model considering security region of wind turbine generators; and 3) calculating the unit commitment model considering the security region of the wind turbine generators by using mixed-integer linear programming method, and obtaining the operation result of the unit commitment considering the security region of the wind turbine generators with frequency response control. The present invention can be widely used in the setting of frequency response parameters of wind turbine generators dispatched in the prior art and the start-stop and output plans of synchronous generator.

Abstract: The present disclosure provides a display panel, a display device and a display method. The display panel includes a base substrate, and an organic electroluminescent device layer, a detection sensor and a color switchable structure which are successively located on the base substrate and are insulated from each other, where the organic electroluminescent device layer includes a plurality of sub-pixels, and the color switchable structure includes sub-units disposed in one-to-one correspondence with the sub-pixels; the sub-units are configured to transmit light emitted by the sub-pixels under the control of applied different signals, or to display light of colors corresponding to the applied signals; and the detection sensor is configured to detect display parameters of the sub-pixels or the sub-units.

Abstract: The present disclosure provides a monitoring, tracing, early-warning and control system and method for virus spreading in a building. Indoor and outdoor environmental parameters of the building can be monitored in real time. Human physiological indexes are obtained in real time to determine a human health state, and moving trajectories of people and droplet spreading trajectories are obtained. Therefore, suspected infected persons and their close contacts are timely and accurately identified, and countermeasures are taken for the suspected infected persons and the close contacts. In addition, a spreading risk in a current indoor environment can be assessed, the indoor environment is ventilated and purified according to a spreading risk assessment result, and local areas of the suspected infected persons and the close contacts are effectively ventilated and purified, so as to reduce the spreading risk.

Abstract: Disclosed is a method for preparing a pyrrolidinyl urea derivative, which acts as a TrkA inhibitor, and further disclosed are an intermediate compound of a compound of formula (I) and a preparation method therefor.

Abstract: Disclosed are a crystal form of a thieno[2,3-c]pyridazine-4(1H)-one compound, a preparation method therefor and the use thereof in the preparation of a drug as an inhibitor of ACC1 and ACC2.

Abstract: The present invention discloses a unit commitment method considering security region of wind turbine generators with frequency response control, and the main steps are: 1) determining security region of wind turbine generators when provides frequency response; 2) based on the security region of the wind turbine generators when provides frequency response, establishing a unit commitment model considering security region of wind turbine generators; and 3) calculating the unit commitment model considering the security region of the wind turbine generators by using mixed-integer linear programming method, and obtaining the operation result of the unit commitment considering the security region of the wind turbine generators with frequency response control. The present invention can be widely used in the setting of frequency response parameters of wind turbine generators dispatched in the prior art and the start-stop and output plans of synchronous generator.

Abstract: Provided are crystalline forms of pyrazine-2(1H)-ketone compound and a preparation method thereof; specifically disclosed are a method for preparing the compound of formula (II) and crystalline forms thereof.

Abstract: Disclosed are a crystal form of a thieno[2,3-c]pyridazine-4(1H)-one compound, a preparation method therefor and the use thereof in the preparation of a drug as an inhibitor of ACC1 and ACC2.

Abstract: Disclosed is a method for preparing a pyrrolidinyl urea derivative, which acts as a TrkA inhibitor, and further disclosed are an intermediate compound of a compound of formula (I) and a preparation method therefor.

Abstract: Provided are preparation methods for the chemical compound represented by formula (I) and an intermediate thereof.

Abstract: Provided are preparation methods for the chemical compound represented by formula (I) and an intermediate thereof.

Abstract: Provided are crystalline forms of pyrazine-2(1H)-ketone compound and a preparation method thereof; specifically disclosed are a method for preparing the compound of formula (II) and crystalline

Abstract: Disclosed is a total flavonoids extract of Gynura formosana Kitam., containing 80%-85% of rutin by weight percent content. The results of pharmacological experiments show that the extract can lower the activity of xanthine oxidase in the liver of a hyperuricemia model mouse and reduce the synthesis of uric acid to a certain degree and has a certain uric acid-lowering effect, and can be used as a potential drug for treating hyperuricemia or gout. The method for preparing the total flavonoids extract of Gynura formosana Kitam. comprises: after an extraction step, selecting a complex enzyme composed of enzymes with a specific composition and a specific ratio for enzymolosis, and further carrying out the step of extracting and concentrating with macroporous resin and isolating and purifying with macroporous resin, so that the HPLC purity of rutin in the resulting total flavonoids extract of Gynura formosana Kitam. reaches 80%-85%.

Abstract: A total flavonoid extract from Gynura formosana Kitam., comprising 80-85% of rutin. A preparation method comprises selecting a complex enzyme consisting of a specific composition and ratio of enzymes for enzymatic hydrolysis, extracting and concentrating by a macroporous resin, and separating and purifying by a macroporous resin. The extract has therapeutic effect on non-alcoholic fatty liver disease.

Abstract: A total flavonoid extract from Gynura formosana Kitam., comprising 80-85% of rutin. A preparation method comprises selecting a complex enzyme consisting of a specific composition and ratio of enzymes for enzymatic hydrolysis, extracting and concentrating by a macroporous resin, and separating and purifying by a macroporous resin. The extract has therapeutic effect on non-alcoholic fatty liver disease.