Patents by Inventor Judit Broda

Judit Broda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing pharmaceutical compounds and intermediate compounds
    Patent number: 9169265
    Abstract: The object of the present invention is a process for preparing the 2-acetoxi-5-(2-fluor-?-cyclopropyl-carbonyl-benzyl)-4,5,6,7-tetrahydro-4H-thieno[3,2-c]pyridine (prasugrel) of the formula (I). The process starts from crystalline 5-trityl-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine of the formula (VI). Further objects of the present invention are two novel crystalline forms of 5-trityl-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine of the formula (VI) and the use thereof for preparing the compound of the formula (V) and process preparing thereof.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: October 27, 2015
    Assignee: EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG
    Inventors: Márta Porcs-Makkay, Balázs Volk, Tamás Gregor, József Barkóczy, Tibor Mezei, Judit Broda, Bálint Nyulasi, György Ruzsics, Enikö Molnár, József Debreczeni, Kálmán Nagy, Angéla Pandur, Zsuzsanna Szent-Királlyi
  • Inorganic salt complexes of vildagliptin
    Patent number: 8877799
    Abstract: The present invention relates to the use of novel vildagliptin complexes for the manufacture of high purity vildagliptin of Formula I and/or pharmaceutical acceptable salts thereof. Further objects of the present invention are pharmaceutically acceptable complexes of vildagliptin and/or amorphous and crystalline forms, anhydrous forms, amorphous and crystalline hydrates, amorphous and crystalline solvates of the complexes and a process for the preparation thereof. Another object of the present invention is the high purity vildagliptin and pharmaceutically acceptable salts thereof prepared form the vildagliptin complexes of the present invention, a process for the preparation thereof and pharmaceutical compositions containing vildagliptin base, pharmaceutically acceptable salts and/or complexes and use thereof for the treatment of type 2 diabetes (NIDDM). The present invention provides pharmaceutically advantageous high purity vildagliptin complexes.
    Type: Grant
    Filed: October 7, 2010
    Date of Patent: November 4, 2014
    Assignee: Egis Gyogyszergynar Nyilvanosan Muekoedoe Reszvenytarsasag
    Inventors: Andras Mravik, Imre Koehegyi, Laszlo Pongo, Balazs Volk, Gabor Nemeth, Jozsef Barkoczy, Kalman Nagy, Gyoergy Ruzsics, Judit Broda, Andras Dancso, Adrienn Keszthelyi, Jozsef Debreczeni
  • INORGANIC SALT COMPLEXES OF VILDAGLIPTIN
    Publication number: 20130005790
    Abstract: The present invention relates to the use of novel vildagliptin complexes for the manufacture of high purity vildagliptin of Formula I and/or pharmaceutical acceptable salts thereof. Further objects of the present invention are pharmaceutically acceptable complexes of vildagliptin and/or amorphous and crystalline forms, anhydrous forms, amorphous and crystalline hydrates, amorphous and crystalline solvates of the complexes and a process for the preparation thereof. Another object of the present invention is the high purity vildagliptin and pharmaceutically acceptable salts thereof prepared form the vildagliptin complexes of the present invention, a process for the preparation thereof and pharmaceutical compositions containing vildagliptin base, pharmaceutically acceptable salts and/or complexes and use thereof for the treatment of type 2 diabetes (NIDDM). The present invention provides pharmaceutically advantageous high purity vildagliptin complexes.
    Type: Application
    Filed: October 7, 2010
    Publication date: January 3, 2013
    Inventors: Andras Mravik, Imre Koehegyi, Laszlo Pongo, Balazs Volk, Gabor Nemeth, Jozsef Barkoczy, Kalman Nagy, Gyoergy Ruzsics, Judit Broda, Andras Dancso, Adrienn Keszthelyi, Jozsef Debreczeni
  • PROCESS FOR PREPARING PHARMACEUTICAL COMPOUNDS AND INTERMEDIATE COMPOUNDS
    Publication number: 20120330018
    Abstract: The object of the present invention is a process for preparing the 2-acetoxy-5-(2-fluor-?-cyclopropyl-carbonyl-benzyl)-4,5,6,7-tetrahydro-4H-tieno[3,2-c]pyridine (prasugrel) of the formula (I). The process starts form crystalline 5-trityl-4,5,6,7-tetrahydro-tieno[3,2-c]pyridine of the formula (VI). Further objects of the present invention are two novel crystalline forms of 5-trityl-4,5,6,7-tetrahydro-tieno[3,2-c]pyridine of the formula (VI) and the use thereof for preparing the compound of the formula (V) and process preparing thereof.
    Type: Application
    Filed: December 21, 2010
    Publication date: December 27, 2012
    Applicant: Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag
    Inventors: Márta Porcs-Makkay, Balázs Volk, Tamás Gregor, József Barkóczy, Tibor Mezei, Judit Broda, Bálint Nyulasi, György Ruzsics, Enikõ Molnár, József Debreczeni, Kálmán Nagy, Angéla Pandur, Zsuzsanna Szent-Királlyi