Patents by Inventor Judith M. White

Judith M. White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF MODELING IN VIVO EFFICACY OF DRUG COMBINATIONS FOR TREATMENT OF VIRAL INFECTIONS
    Publication number: 20240127967
    Abstract: Methods of modeling the in vivo efficacy of drug combinations for the treatment or prevention of viral infection are described. The described methods combine data for single drugs and drug combinations from pharmacokinetic, pharmacodynamic, and viral dynamics models under a series of estimated in vivo drug potencies to provide predictions of the in vivo effects of the drug combinations. These predictions can be used to more accurately select drugs and drug treatment regimens that can be successful in controlling viral infection in animal studies, clinical trials and in medical or veterinary interventions. Also described is a method of treating or preventing filovirus infections using combinations of orally available drugs based on predictions from the modeling methods.
    Type: Application
    Filed: February 9, 2022
    Publication date: April 18, 2024
    Applicants: University of Virginia Patent Foundation, Fred Hutchinson Cancer Research Center
    Inventors: Judith M. White, Shuang Xu, Joshua T. Schiffer, Gene G. Olinger, Courtney L. Finch, Julie Dyall, Stephen J. Polyak, Lisa Johansen
  • ANTINEMATODAL METHODS AND COMPOSITIONS
    Publication number: 20170086465
    Abstract: There are provided methods and compositions useful in cell-cell fusion using Fusion Family (FF) proteins of nematode origin. There are further provided antinematodal methods and compositions, utilizing fusogenic proteins of the nematode Fusion Family.
    Type: Application
    Filed: October 17, 2016
    Publication date: March 30, 2017
    Inventors: Benjamin Podbilewicz, Ori Avinoam, Judith M. White
  • Antinematodal methods and compositions
    Patent number: 9468660
    Abstract: There are provided methods and compositions useful in cell-cell fusion using Fusion Family (FF) proteins of nematode origin. There are further provided antinematodal methods and compositions, utilizing fusogenic proteins of the nematode Fusion Family.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: October 18, 2016
    Assignees: Technion Research and Development Foundation Ltd., University of Virginia Patent Foundation
    Inventors: Benjamin Podbilewicz, Ori Avinoam, Judith M. White
  • ANTINEMATODAL METHODS AND COMPOSITIONS
    Publication number: 20130336939
    Abstract: There are provided methods and compositions useful in cell-cell fusion using Fusion Family (FF) proteins of nematode origin. There are further provided antinematodal methods and compositions, utilizing fusogenic proteins of the nematode Fusion Family.
    Type: Application
    Filed: January 31, 2012
    Publication date: December 19, 2013
    Applicants: UNIVERSITY OF VIRGINIA PATENT FOUNDATION, TECHNION RESEARCH AND DEVELOPEMENT FOUNDATION LTD.
    Inventors: Benjamin Podbilewicz, Ori Avinoam, Judith M. White
  • Method of treating a viral condition by inhibiting membrane fusion
    Patent number: 6080791
    Abstract: A method of preventing and treating a viral condition caused by an enveloped virus is described, comprising using a therapeutically effective amount of a compound selected from the group consisting of a substituted hydroquinone and the corresponding benzoquinone, wherein said hydroquinone comprises a 2-R.sup.1, 3-R.sup.2 -1,4-hydroquinone where at least one of R.sup.1 and R.sup.2 include a carbon linkage to the benzene ring of the hydroquinone. Particularly useful compounds include 5,8-dihydro-5,8-methano-1,4-naphthalenediol, 1,4-naphthoquinone, 3', 6'-dihydroxybenzo-norbornane, tert-butylhydroquinone, other diols, e.g. 1,5-naphthalenediol, and alkylated diols, e.g. 4-methoxy-1-naphthol.
    Type: Grant
    Filed: July 24, 1992
    Date of Patent: June 27, 2000
    Assignees: Seres Laboratories, Inc., University of California
    Inventors: Dale L. Bodian, Judith M. White, Irwin D. Kuntz, Jay F. Stearns, R. Bryan Yamasaki