Patents by Inventor Judith Margreet Rensen
Judith Margreet Rensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180200426Abstract: A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.Type: ApplicationFiled: January 25, 2018Publication date: July 19, 2018Inventors: JOHAN FREDERIK DIJKSMAN, FRITS TOBI DE JONGH, MICHEL GERARDUS PARDOEL, ANKE PIERIK, JUDITH MARGREET RENSEN, JEFF SHIMIZU, HANS ZOU, REMUS ALBU, VENTZESLAV IORDANOV, HANS MARC BERT BOEVE
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Patent number: 9915523Abstract: The invention relates to a system for monitoring a position of a distal end of a tube with respect to a blood vessel of a mammal. The system comprises a source for generating an outgoing beam of electromagnetic radiation having a predefined electromagnetic spectrum. The system furthermore comprises a guideway for guiding the outgoing beam to the distal end, and for guiding an incoming beam of electromagnetic radiation reflected by surroundings of the distal end in response to said outgoing beam to a measurement arrangement, which is arranged for measuring a parameter associated with an electromagnetic spectrum of the incoming beam. The system furthermore comprises a comparator arrangement for comparing said parameter with a reference parameter associated with a reference electromagnetic spectrum representing a predefined location of the distal end inside the mammal.Type: GrantFiled: June 10, 2011Date of Patent: March 13, 2018Assignee: Koninklijke Philips N.V.Inventors: Judith Margreet Rensen, Wouter Harry Jacinth Rensen
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Patent number: 9878094Abstract: A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.Type: GrantFiled: November 6, 2007Date of Patent: January 30, 2018Assignee: STOCO 10 GMBHInventors: Johan Frederik Dijksman, Frits Tobi De Jongh, Michel Gerardus Pardoel, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Hans Zou, Remus Albu, Ventzeslav Iordanov, Hans Marc Bert Boeve
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Patent number: 9550050Abstract: An electronic capsule (100) is provided. The capsule (100) has a discrete drive element (300) comprising: a housing (109), electronics for making the electronic capsule (100) operable, a pumping mechanism (115) for dosing and displacing a substance, a power source (105) for powering the electronic capsule (100) and enabling the electronics and the pumping mechanism (115) to operate, and a locking mechanism (130); and a discrete payload element (200) comprising: a housing (109), a reservoir (210) for storing the substance, one or more openings (250) in the housing (109) for releasing the substance from the reservoir (210) and a locking mechanism (230) for engaging the drive element locking mechanism (130). Engagement of the drive element locking mechanism (130) with the payload element locking mechanism (230) secures the drive element (300) to the payload element (200), thereby making the electronic capsule (100) operable and specific.Type: GrantFiled: September 20, 2007Date of Patent: January 24, 2017Assignee: Medimetrics Personalized Drug Delivery B.V.Inventors: Johan Frederik Dijksman, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Hans Zou, Michel Pardoel, Frits Tobi De Jongh
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Patent number: 9155481Abstract: An apparatus for monitoring whether or not a distal end of a tube is positioned inside a blood vessel includes a heating element configured to heat the tube distal end, and a sensor arrangement configured to generate a measurement signal indicative for heat transferred by exterior of the distal end. The apparatus further includes a comparator configured to compare the measurement signal with a reference level. The reference level equals a value attained by the measurement signal in response to a minimum flow velocity in the blood vessel. Further, a system is configured to exchange a liquid with a mammal via a blood vessel. The system includes the apparatus having the tube.Type: GrantFiled: May 26, 2010Date of Patent: October 13, 2015Assignee: Koninklijke Philips N.V.Inventors: Marieke Klee, Jacob Roger Haartsen, Judith Margreet Rensen
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Patent number: 8990018Abstract: A kit includes a swallowable capsule (1, 45) with a potentiometric sensor (3), such as a pH sensor, with an unfilled electrolyte cell (31). The kit further includes a separate container (46) containing a liquid electrolyte. The kit can, e.g., be packed in a blister package. After unpacking the capsule the electrolyte cell (31) is filled with the electrolyte.Type: GrantFiled: March 24, 2009Date of Patent: March 24, 2015Assignee: Medimetrics Personalized Drug Delivery B.V.Inventors: Johan Frederik Dijksman, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Petrus Leonardus Adrianus Van Der Made, Michel Gerardus Pardoel, Frits Tobi De Jongh, Johan Gerard Kleibeuker
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Patent number: 8852172Abstract: An ingestible electronic capsule (100) for introduction into the bodily lumen comprises a circuit board with at least one electronic component (4, 5, 7, 8, 9, 11, 12, 13, 14). The circuit board is formed from a flex foil (10), thereby reducing the number of components and improving the robustness and reliability of the ingestible electronic capsule (100).Type: GrantFiled: November 5, 2007Date of Patent: October 7, 2014Assignee: Medimetrics Personalized Drug DeliveryInventors: Johan Frederik Dijksman, Frits Tobi De Jongh, Michel Gerardus Pardoel, Claude Jean-Marie Malaurie, Yvan O. J. G. Droinet, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Hans Zou, Remus Albu
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Patent number: 8597279Abstract: A capsule and methodology for dispensing a medicament in the gastrointestinal tract of a mammal is disclosed, the gastrointestinal tract having tissue sites of interest. The capsule may include a medicament reservoir; medicament dispensing means such as a plurality of piezoelectric droplet jet nozzle dispensers; a power source; electronic control circuitry means and/or detecting means capable of communicating with a medicament dispensing means for regulating the amount and time interval for dispensing of the medicament into the gastrointestinal tract by the medicament dispensing means; and a non-digestible outer protective shell housing, e.g., the medicament reservoir, medicament dispensing means and electronic control circuitry means.Type: GrantFiled: October 17, 2007Date of Patent: December 3, 2013Assignee: Medimetrics Personalized Drug Delivery, Inc.Inventors: Johan Frederik Dijksman, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Hans Zou, Ivar Schram
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Publication number: 20130083331Abstract: The invention relates to a system (101) for monitoring a position of a distal end (102) of a tube (104) with respect to a blood vessel (106) of a mamma. The system comprises a source (110) for generating an outgoing beam (112) of electromagnetic radiation having a predefined electromagnetic spectrum. The system furthermore comprises a guideway (114) for guiding the outgoing beam to the distal end, and for guiding an incoming beam (116) of electromagnetic radiation reflected by surroundings of the distal end in response to said outgoing beam to a measurement arrangement (120) which is arranged for measuring a parameter (122) associated with an electromagnetic spectrum of the incoming beam. The system furthermore comprises a comparator arrangement (124) for comparing said parameter with a reference parameter (126) associated with a reference electromagnetic spectrum representing a predefined location of the distal end inside the mammal.Type: ApplicationFiled: June 10, 2011Publication date: April 4, 2013Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Judith Margreet Rensen, Wouter Harry Jacinth Rensen
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Publication number: 20130035585Abstract: The invention relates to a preparing apparatus for preparing an influencing procedure for influencing a subject. The preparing apparatus (1) comprises a subject coil (3) for generating a magnetic resonance image of he subject (7), an instrument guide device (5) for guiding an instrument (6) for influencing the subject (7), a marker (9) being visible in the magnetic resonance image, and an attaching element for attaching the instrument guide device (5) to the subject coil (3) in a known spatial relationship. Since the spatial relationship between the instrument guide device (5) and the subject coil (3) is known, if they are attached to each other, a time consuming registration procedure for registering an influence trajectory, which has been planned based on the magnetic resonance image, and the instrument guide device (5) can be avoided.Type: ApplicationFiled: March 31, 2011Publication date: February 7, 2013Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Hubert Cecile Francois Martens, Judith Margreet Rensen, Michel Marcel Jose Decre
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Publication number: 20120071783Abstract: The invention relates to an apparatus (102) capable of accurately monitoring whether or not a distal end of a tube is positioned inside a blood vessel. The apparatus comprises a heating element (106) configured for heating the distal end and a sensor arrangement (110) for generating a measurement signal (114) indicative for heat transferred by an exterior of the distal end. For the purpose of comparing the measurement signal (114) with a reference level, the apparatus furthermore comprises a comparator arrangement (116). Herein the reference level equals a value attained by the measurement signal (114) in response to a minimum flow velocity in the blood vessel. The invention furthermore relates to a system (102) for exchanging a liquid with a mammal via a blood vessel. The system comprises a tube provided with the apparatus according to the invention.Type: ApplicationFiled: May 26, 2010Publication date: March 22, 2012Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Marieke Klee, Jacob Roger Haartsen, Judith Margreet Rensen
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Publication number: 20110245713Abstract: A medical device comprising a probe for measurement temperature data of tissue within a patient's body is proposed. The probe (2) comprises a flexible substrate (3) attached to a medical device core (5), the flexible substrate (3) comprising one or more thermopiles (7) and may furthermore comprise resistors for measuring an absolute temperature and heat sources for locally applying heat. The thermopiles can be processed directly on a flexible polymer carrier or, alternatively, on a silicon substrate and transferred to a flexible carrier (3) enabling both, a highly flexible substrate (3) and very small structural dimensions for the thermopiles (7) and, possibly, the resistors and heat sources. Accordingly, measurement of temperature gradients of tissue being in contact to the medical device may be performed at high resolution allowing reliable detection of temperature anomalies e.g. due to malign tissue.Type: ApplicationFiled: November 9, 2009Publication date: October 6, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Judith Margreet Rensen, Jaap Haartsen, Mareike Klee, Drazenko Babic, Bernardus Hendrikus Wilhelmus Hendriks, Christianus Martinus Van Heesch, Bout Marcelis
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Publication number: 20110017612Abstract: The inventions relates to a kit comprising a swallowable capsule (1, 45) with a potentiometric sensor (3), such as a pH sensor, with an unfilled electrolyte cell (31). The kit further includes a separate container (46) containing a liquid electrolyte. The kit can, e.g., be packed in a blister package. After unpacking the capsule the electrolyte cell (31) is filled with the electrolyte.Type: ApplicationFiled: March 24, 2009Publication date: January 27, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Johan Frederik Dijksman, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Petrus Leonardus Adrianus Van Der Made, Michel Gerardus Pardoel, Frits Tobi De Jongh, Johan Gerard Kleibeuker
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Publication number: 20100228082Abstract: A device or support, system and method are provided for precisely targeted and/or highly controlled interaction with a targeted cell or tissue in a body, with the support providing an ergonomic connecting interface for selectively connecting the support to a cell or tissue with at least minimal adverse affect to such cell or tissue, the system providing a remote facility that may be operatively associated with the support, and the method providing steps for employing the support and/or system so as to, inter alia, improve treatment, diagnostic and/or monitoring techniques and increase sensitivity and specificity with respect to interacting with, for example, diseased or abnormal cells or tissue without adversely effecting surrounding healthy cells or tissue, and/or the body in general.Type: ApplicationFiled: April 12, 2007Publication date: September 9, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Hans Zou, Stein Kuiper, Bernardus Hendrikus Wilhelmus Hendriks, Jan Frederik Suijver, Anke Pierik, Judith Margreet Rensen, Johan Frederik Dijksman, Jeff Shimizu, Jacob Marinus Jan Den Toonder
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Publication number: 20100063486Abstract: An electronic capsule (100) is provided. The capsule (100) has a discrete drive element (300) comprising: a housing (109), electronics for making the electronic capsule (100) operable, a pumping mechanism (115) for dosing and displacing a substance, a power source (105) for powering the electronic capsule (100) and enabling the electronics and the pumping mechanism (115) to operate, and a locking mechanism (130); and a discrete payload element (200) comprising: a housing (109), a reservoir (210) for storing the substance, one or more openings (250) in the housing (109) for releasing the substance from the reservoir (210) and a locking mechanism (230) for engaging the drive element locking mechanism (130). Engagement of the drive element locking mechanism (130) with the payload element locking mechanism (230) secures the drive element (300) to the payload element (200), thereby making the electronic capsule (100) operable and specific.Type: ApplicationFiled: September 20, 2007Publication date: March 11, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Johan Frederik Dijksman, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Hans Zou, Michel Pardoel, Frits Tobi De Jongh
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Publication number: 20100056874Abstract: A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.Type: ApplicationFiled: November 6, 2007Publication date: March 4, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Johan Frederik Dijksman, Frits Tobi De Jongh, Michel Gerardus Pardoel, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Hans Zou, Remus Albu, Ventzeslav Iordanov, Hans Marc Bert Boeve
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Publication number: 20100056396Abstract: The present invention relates to an apparatus 1 for transferring cells 2 suspended in a fluid 3 from the fluid 3 to a substrate 17. The apparatus 1 comprises a transfer device 8 having an exterior surface 9, an interior cavity 10, and a plurality of passages 11 each having a first end 12 at the exterior surface 9 and a second end 13 in fluid 5 communication with the cavity 10 and each having a diameter corresponding to a predefined size of the cells 2 to be transferred. The apparatus further comprises a pressure regulating device 14 capable of regulating a pressure in the cavity 10 so as to establish a pressure difference between the first and second ends 12, 13 of each passage 11, a container 4 for containing the fluid 3, and a flow device 7 capable of causing the fluid 3 to flow across the 10 exterior surface 9 when in contact with the fluid 3.Type: ApplicationFiled: November 28, 2007Publication date: March 4, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Dirkjan Bernhard Van Dam, Simone Irene Elisabeth Vulto, Thomas Jan De Hoog, Judith Margreet Rensen
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Publication number: 20100049012Abstract: An ingestible electronic capsule (100) for introduction into the bodily lumen comprises a circuit board with at least one electronic component (4,5,7,8,9,11, 12, 13, 14). The circuit board is formed from a flex foil (10), thereby reducing the number of components and improving the robustness and reliability of the ingestible electronic capsule (100).Type: ApplicationFiled: November 5, 2007Publication date: February 25, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Johan Frederik Dijksman, Frits Tobi De Jongh, Michel Gerardus Pardoel, Claude Jean-Marie Malaurie, Yvan O.J.G. Droinet, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Hans Zou, Remus Albu
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Publication number: 20100049120Abstract: A capsule and methodology for dispensing a medicament in the gastrointestinal tract of a mammal is disclosed, the gastrointestinal tract having tissue sites of interest. The capsule may include a medicament reservoir; medicament dispensing means such as a plurality of piezoelectric droplet jet nozzle dispensers; a power source; electronic control circuitry means and/or detecting means capable of communicating with a medicament dispensing means for regulating the amount and time interval for dispensing of the medicament into the gastrointestinal tract by the medicament dispensing means; and a non-digestible outer protective shell housing, e.g., the medicament reservoir, medicament dispensing means and electronic control circuitry means.Type: ApplicationFiled: October 17, 2007Publication date: February 25, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Johan Frederik Dijksman, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Hans Zou, Ivar Schram
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Publication number: 20100045309Abstract: A fluid sensor for use within the gastro-intestinal tract of a human being is disclosed. The sensor includes a sensing coil which is immersible in the sample fluid of the gastro-intestinal tract; a signal generator in electrical with the sensing coil for applying an electrical current pulse to the sensing coil; a signal receiver in communication with the sensing coil for measuring an electrical reflection relative to said electrical current pulse; and a data processor for receiving the electrical reflection and for calculating data representative of at least one property, such as pH of the sample fluid based on the electrical reflection. The fluid sensor can also include a reference coil for calibrating the sensing coil. The sensor coil and reference coil can be encapsulated in a swallowable pill shell. The sensor coil can also function as an antenna for transmitting and receiving signals to/form a remote location.Type: ApplicationFiled: December 26, 2007Publication date: February 25, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Han Zou, Lucian Remus Albu, Jeff Shimizu, Johan Frederik Dijksman, Anke Pierik, Judith Margreet Rensen, Adam Schleicher, Frits Tobi De Jongh