Abstract: In certain aspects, the present disclosure relates to novel radiopharmaceutical ketone molecules, including acetoacetate (AcAc) and/or beta-hydroxybutyrate (BHB), and methods of using one or more radiopharmaceutical ketone molecules or radiopharmaceutical compositions as imaging agents or tracers in positron emission tomography (PET) or combination PET and magnetic resonance imaging (MRI), e.g., as ketone-PET tracers. The methods may be used in diagnostic imaging methodologies in Alzheimer's disease, cognitive impairment, and other conditions of altered cerebral metabolism.

Abstract: The present disclosure relates to methods for the treatment of Infantile Spasms and/or the prevention of spasms of Infantile spasms. The methods include administering compositions comprising at least one compound capable of elevating ketone body concentrations in a subject in need thereof (e.g., ketogenic compounds), administered in an amount effective for treatment of Infantile Spasms and or the prevention of spams of Infantile Spasms. In one embodiment, the composition includes medium chain triglycerides (MCT). The composition may be administered as an oral dosage forms, in particular, a nutritional drink comprising at least one compound capable of elevating ketone body concentrations in a subject.

Abstract: The invention relates compositions of medium chain triglycerides (MCTs), and to methods for treatment with such compositions to treat conditions associated with reduced neuronal metabolism, for example Alzheimer's disease.

Abstract: This invention relates to a method of treating nerve damages in humans, and more particularly, to a noninvasive, nontraumatic method which comprises the steps of applying an essentially monochromatic light to the skin area adjacent to the damaged nerve region of the body.