Abstract: An inflatable topper structure for a pickup truck bed is provided. The inflatable topper structure includes an inflatable topper body and a side bar structure for fixing the inflatable topper body to a pickup truck bed, where the side bar structure includes a first side bar and a second side bar; the first side bar is connected in a matched manner between a right side wall of the inflatable topper body and the pickup truck bed; the second side bar is connected in a matched manner between a left side wall of the inflatable topper body and the pickup truck bed; the first side bar and the second side bar are symmetrically arranged and each fixedly locked to the pickup truck bed; a top of each of the first side bar and the second side bar is provided with a groove.

Abstract: An enclosure for an electronic device includes a metal substrate, a porous anodic oxide layer overlaying the metal substrate, and a hydrothermal sealant disposed on the anodic oxide layer, the hydrothermal sealant including a molten salt.

Abstract: A method is provided for treatment of atherosclerotic cardiovascular disease in a subject in need thereof by administering a statin pharmaceutical composition to the subject when the subject is qualified for over-the-counter access to the statin pharmaceutical composition. In some embodiments, the statin pharmaceutical composition includes atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, or simvastatin as an active ingredient.

Abstract: The present invention provides engineered human alpha-galactosidase polypeptides and compositions thereof. The engineered human alpha-galactosidase polypeptides have been optimized to provide improved thermostability, serum stability, improved cellular uptake, stability under both acidic (pH<4) and basic (pH>7) conditions, reduced immunogenicity, and improved globotriaosylceramide removal from cells. The invention also relates to the use of the compositions comprising the engineered human alpha-galactosidase polypeptides for therapeutic purposes.

Abstract: Methods and apparatus for vaporizing liquid into the surrounding environment, including directing liquid from a liquid source to a vaporization port where the vaporization port has lateral dimensions varying from 10 um to 300 um, applying heat to the liquid in the vaporization port with an at least one heating element located in thermal communication to the vaporization port, and releasing vaporized liquid from the vaporization port into the surrounding environment so that fluid is transported through the depth of the structure.

Abstract: Compact packages including microelectromechanical system (MEMS) devices and multiple application specific integrated circuits (ASICs) are described. These packages are sufficiently small to be applicable to contexts in which space requirements are particularly strict, such as in consumer electronics. These packages involve vertical die stacks. A first ASIC may be positioned on one side of the die stack and another ASIC may be positioned on the other side of the die stack. A die including a MEMS device (e.g., an accelerometer, gyroscope, switch, resonator, optical device) is positioned between the ASICs. Optionally, an interposer serving as cap substrate for the MEMS device is also positioned between the ASICs. In one example, a package of the types described herein has an extension of 2 mm×2 mm in the planar axes and less than 500-800 ?m in height.

Abstract: Plasmonic substrates are provided which may be used in a variety of optoelectronic devices, e.g., biosensors and photodetectors. The plasmonic substrate may comprise a layer of graphene and a plurality of discrete, individual transition metal chalcogenide nanodomes distributed on a surface of the layer of graphene, each nanodome surrounded by bare graphene. Methods for making and using the plasmonic substrates are also provided.

Abstract: An apparatus for adjusting a shoe and methods for making and using the same. A relative movement can be generated between a platform and a model foot wearing the shoe such that the platform contacts the shoe and the model foot adjusts the shoe via the relative movement. Advantageously, the model foot can be a surrogate to a human foot in adjusting the shape of the shoe. The model foot can stretch the shoe in the same manner as human walk. A person can experience great comfort when wearing the stretched shoe. The model foot can simulate the mechanical characteristics of the natural foot. The model foot can simulate gait of a natural foot and the stretching of the shoe can be further customized.

Abstract: Methods and apparatus for vaporizing liquid into the surrounding environment, including directing liquid from a liquid source to a vaporization port where the vaporization port has lateral dimensions varying from 10 um to 300 um, applying heat to the liquid in the vaporization port with an at least one heating element located in thermal communication to the vaporization port, and releasing vaporized liquid from the vaporization port into the surrounding environment so that fluid is transported through the depth of the structure.

Abstract: Systems, methods and data structures for the processing of data for the secure creation, administration, manipulation, processing, and storage of electronic data useful in the processing of electronic payment transactions and other secure data processes. Aspects of such systems include trusted platforms by which networked communication devices and merchant systems may registered as trusted entities. Information associated with particular payment means, such as accounts or payment tokens, can be stored on device(s) secure data sets known as virtual or electronic wallets, or in the form of secure payment tokens. Among other improvements, the invention enables the use of multiple payment accounts to fund purchases and other electronic transactions.

Abstract: A vehicle system includes a vehicle body defining a vehicle interior and a vehicle exterior, one or more detection devices including at least one of a microphone and a camera structurally configured to receive data indicative of conditions within the vehicle interior or on the vehicle exterior, a sanitization device, and a controller communicatively coupled to the one or more detection devices and the sanitization device, the controller including a processor and a non-transitory computer readable and executable instruction set, which when executed, causes the processor to receives data from the one or more detection devices, determine a surface at least one of within the vehicle interior or on the vehicle exterior contacted by a user based at least in part on the data from the one or more detection devices, and direct the sanitization device to sanitize the surface.

Abstract: A wrist brace for providing support to carpal bones within the wrist includes an elongated strap sized and configured to encircle a wrist; a first bracing member on the strap and configured for positioning on a volar side of a wrist; and a second bracing member spaced apart from the first bracing member on the strap and configured for positioning on the dorsal side of a wrist; wherein the first and second bracing members extend outward from the elongated strap and have a surface area that, together with the elongated strap, supports the carpal bones within the wrist.

Abstract: Systems and methods enhanced authentication techniques using virtual persona. An example method includes receiving a request associated with authorization of a user. Information identifying a virtual persona associated with the user is accessed, the virtual persona comprising meshes. Confidence measures associated with the user's identity are determined based on the meshes. The request is responded to based on the confidence measures.

Abstract: The presently disclosed subject matter provides methods of isolating biomarker cells from a liquid sample, and related methods of capturing DNA or RNA released from biomarker cells.

Abstract: An extreme vacuum cooling (EVC) method and apparatus is disclosed for rapid cooling, food treatment, and flavor infusion in commercial kitchens and food processing plants. Operating under ultra-low pressure with adaptive chamber pressure control, the EVC apparatus eliminates liquid splash and optimizes marinating and brining, achieving substantial time and energy savings. Available in single-unit and dual-module designs, this technology and apparatus enables swift, flexible, safer, less labor-intensive, and high-throughput food preparation operations.

Abstract: The present invention includes a device for securing bed sheets on a mattress having a bottom, a top surface, and a periphery including side and end walls, the device including a sleeve or band having side panels, end panels corner panels and a top edge, the sleeve or band can be fitted around the mattress periphery side and end walls. A securing, gripping, or positioning element, e.g., elastic or other suitable securing element, can be provided at one or more locations on the sleeve or band, wherein the securing, gripping, or positioning element(s) can be placed around the mattress periphery at a position below the mattress top surface. The securing, gripping, or positioning element(s) are capable of securing the bed sheets in between the sleeve or band and the mattress.

Abstract: A user preference hierarchy is determined from user response to images. Images may be tagged using machine learning models trained to determine values for images. Products are clustered according to product vectors. Images of products within a cluster are clustered according to composition and groups of images are selected from image clusters for soliciting feedback regarding user preference for products of a cluster. Feedback is used to train a user preference model to estimate affinity for a product vector. A user may provide feedback regarding a price point and products are weighted according to a distribution about the price point. The distribution may be asymmetrical according to direction of movement of the price point. Filters may be dynamically defined and presented to a user based on popularity and frequency of occurrence of attribute-value pairs of search results and based on feedback regarding the search results.

Abstract: A medical system is provided comprising a medical device including a handle and a mechanism for moving a distal end of the medical device; an auxiliary medical device comprising a basket retrieval device including a basket sheath disposed over a basket wire and received into a working channel of the medical device; a knob assembly in communication with the basket retrieval device, the knob assembly rotatable so that the basket sheath, wire, or both move within the working channel; and a base removably connecting the auxiliary medical device to the handle wherein the handle and the base are configured to be simultaneously gripped with a hand, and wherein the mechanism is configured to be moved with a first finger to move the distal end of the medical device and the knob assembly is configured to be rotated with a second finger to move the basket sheath wire, or both.

Abstract: Systems and methods are provided for managing and rewarding sharing of user data via a computing device with a requesting device. A privacy risk score is received for the requesting device characterizing a degree of cyber risk for sharing data. Initial privacy settings are received for the user via a GUI in response to the privacy risk score characterizing the user data allowable for sharing. A reward incentive is then automatically determined based on the privacy risk and the initial privacy settings for sharing additional user data with the requesting device beyond that identified by the initial privacy settings. Then, in response to an override from the GUI overriding the initial privacy settings to accept the reward incentive and thereby allow sharing of the additional user data beyond the initial range: updated privacy settings are determined and the sharing of the user data is limited to the updated privacy settings.