Abstract: A device for embedding a tissue sample includes a tissue cassette (10) and a mold (20). The tissue cassette (10) includes a frame (120), a top cover (100) coupled to the frame (120), and a bottom cover (110) coupled to the frame (120). The mold (20) defines a recess (220). The top and bottom covers hold the tissue sample therebetween. The top and bottom covers are capable of moving from a first position to a second position with respect to the frame (120), and in the second position the bottom cover (110) extend beyond a bottom face (123) of the frame (120) and is separated from the frame (120) and the top cover (100); the tissue cassette (10) is mountable on the mold (20), and the recess (220) is configured to receive the bottom cover (110) in the second position, such that a paraffin block (90) obtained by dispensing and cooling molten paraffin in the mold (20) is detachable from the mold (20) while the bottom cover (110) is remained in the mold (20).

Abstract: Some embodiments include apparatuses and electrical models associated with the apparatus. One of the apparatuses includes an integrated circuit having a die; a package substrate; first conductive connections coupled between the die and a first side of the package substrate; second conductive connections located on a second side of the package substrate opposite from the first side. The second conductive connections are coupled to the first conductive connections through conductive paths in the package substrate. The first conductive connections and the conductive connections are associated with an S-parameter of an electrical model of the integrated circuit package. The electrical model further includes at least one of a current value associated with a power rail of the integrated circuit package, an impedance target associated with a location at the integrated circuit package, and a mapping associated with the first and second conductive connections.

Abstract: A cassette and an embedding method using the same are provided. The cassette includes: a frame including an accommodating member, the accommodating member defining an accommodating chamber and configured to accommodate the tissue in the accommodating chamber, the accommodating chamber having a first opening and a second opening opposite to each other; a first holder detachably connected to the frame, and closing the first opening of the accommodating chamber; and a second holder connected to the frame, and configured to slide relative to the frame to open or close the second opening of the accommodating chamber.

Abstract: A cassette and an embedding method using the same are provided. The cassette includes: a frame including an accommodating member configured to accommodate the tissue, the accommodating member having a first opening and a second opening opposite to each other; a first holder connected to the frame, and configured to rotate relative to the frame to open or close the first opening of the accommodating member; and a second holder connected to the frame, and configured to rotate relative to the frame to open or close the second opening of the accommodating member.

Abstract: A cassette and an embedding method using the same are provided. The cassette includes: a frame including an accommodating member, the accommodating member defining an accommodating chamber and configured to accommodate the tissue in the accommodating chamber, the accommodating chamber having a first opening and a second opening opposite to each other; a first holder detachably connected to the frame, and closing the first opening of the accommodating chamber; and a second holder connected to the frame, and configured to slide relative to the frame to open or close the second opening of the accommodating chamber.

Abstract: A cassette and an embedding method using the same are provided. The cassette includes: a frame including an accommodating member configured to accommodate the tissue, the accommodating member having a first opening and a second opening opposite to each other; a first holder connected to the frame, and configured to rotate relative to the frame to open or close the first opening of the accommodating member; and a second holder connected to the frame, and configured to rotate relative to the frame to open or close the second opening of the accommodating member.

Abstract: A cassette, including: a frame defining an accommodating chamber; an intermediate member coupled to the frame and movably arranged in the accommodating chamber, the intermediate member having a through hole in the middle; a cover rotatably connected to the intermediate member and configured to be closed to cover the through hole; a base connected to the intermediate member and configured to receive the tissue sample; and a retaining member connected to the cover and configured to pass through the through hole to retain the tissue sample in the base, the retaining member having a three-dimensional structure made of a two-dimensional porous material.

Abstract: A cassette, including: a frame defining an accommodating chamber; a retaining assembly coupled to the frame and movably arranged in the accommodating chamber; and a base detachably coupled to the retaining assembly and configured to be moved along with the retaining assembly, the retaining assembly being configured to retain the tissue sample in the base. The retaining assembly and the base are movable between a first position where the base is received in the accommodating chamber and a second position where the base is protruded out of the accommodating chamber, and the base is configured to be detached from the retaining assembly when the retaining assembly is in the second position.

Abstract: A cassette for holding and orienting a tissue sample, includes a frame, a retaining assembly and a base. The frame defines an accommodating chamber. The retaining assembly is movably coupled to the frame and has a biasing member. The base is detachably coupled to the retaining assembly. The biasing member is configured to urge the tissue sample towards the base to holding the tissue sample between the base and the retaining assembly. The base is movable along with the retaining assembly relative to the frame between a first position where the base is received in the accommodating chamber and a second position where the base is protruded from the accommodating chamber. The cassette can be used both in tissue processing and embedding, and the orientation of the tissue sample is not necessary to change.

Abstract: A knife holder is provided. The knife holder includes: a base; a pressure plate pivotally arranged to the base and configured to releasably clamp a blade in a sectioning position together with the base; and a blade changing apparatus embedded in the base and configured to output an unused blade out of the base to change a used blade.

Abstract: The present disclosure relates to a blade holder (100), a blade moving system (1000) and a microtome (2000). The blade holder (100) includes a base (110) defining a blade groove (112) and a slide groove (114), the blade groove (112) being configured to accommodating a blade (900); a slide rail (120) slidably accommodated in the slide groove (114); and an engagement assembly (130) mounted to the slide rail (120) and configured to engage the blade (900) such that the blade (900) is slidable along the blade groove (112) with sliding of the slide rail (120) in the slide groove (114). By using the blade holder (100) according to embodiments of the present disclosure, the blade (900) can be moved to the left or right along the blade groove (112) by sliding the slide rail (120) in the slide groove (114), thereby facilitating fully use of the blade (900).

Abstract: Embodiments of the present disclosure relate to a blade holder system based on radio frequency identification (RFID) technology and a controlling method thereof. The blade holder system comprises a blade dispenser, including a blade and a radio frequency identification (RFID) tag, the RFID tag including ID data relating to the blade dispenser; a blade holder, including a radio frequency identification (RFID) reading/writing unit, configured to establish a wireless communication connection with the RFID tag so as to receive the ID data from the RFID tag; and a controller, configured to receive the ID data from the RFID reading/writing unit, to compare the ID data with preset authorization data, and to enable the blade holder to use the blade in the blade dispenser when the ID data matches with the authorization data.

Abstract: Some embodiments include apparatuses and electrical models associated with the apparatus. One of the apparatuses includes an integrated circuit having a die; a package substrate; first conductive connections coupled between the die and a first side of the package substrate; second conductive connections located on a second side of the package substrate opposite from the first side. The second conductive connections are coupled to the first conductive connections through conductive paths in the package substrate. The first conductive connections and the conductive connections are associated with an S-parameter of an electrical model of the integrated circuit package. The electrical model further includes at least one of a current value associated with a power rail of the integrated circuit package, an impedance target associated with a location at the integrated circuit package, and a mapping associated with the first and second conductive connections.