Patents by Inventor Juergen Fingerle

Juergen Fingerle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radiolabeled cannabinoid receptor 2 ligand
    Patent number: 10227308
    Abstract: The present invention relates to a compound of formula (I) wherein R1 is defined as in the description and in the claims. The compound of formula (I) can be used as radiolabeled ligand.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: March 12, 2019
    Assignees: HOFFMANN-LA ROCHE INC., EIDGENÖSSISCHE TECHNISCHE HOCHSCHULE ZÜRCIH, UNIVERSITÄT ZÜRICH
    Inventors: Simon M. Ametamey, Juergen Fingerle, Luca Gobbi, Uwe Grether, Ahmed Haider, Thomas Hartung, Linjing Mu, Leo Nicholls, Mark Rogers-Evans, Christoph Ullmer
  • RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND
    Publication number: 20170166534
    Abstract: The present invention relates to a compound of formula (I) wherein R1 is defined as in the description and in the claims. The compound of formula (I) can be used as radiolabeled ligand.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 15, 2017
    Applicants: Hoffmann-La Roche Inc., EIDGENÖSSISCHE TECHNISCHE HOCHSCHULE ZÜRICH, UNIVERSITÄT ZÜRICH
    Inventors: Simon M. Ametamey, Juergen Fingerle, Luca Gobbi, Uwe Grether, Ahmed Haider, Thomas Hartung, Linjing Mu, Leo Nicholls, Mark Rogers-Evans, Christoph Ullmer
  • Tetranectin-apolipoprotein A-I, lipid particles containing it and its use
    Patent number: 9187550
    Abstract: A lipid particle comprising an apolipoprotein, a phosphatidylcholine and a lipid, such as a phospholipid, fatty acid or steroid lipid. In one embodiment the lipid particle comprises only one apolipoprotein. In one embodiment the lipid particle is consisting of one apolipoprotein, a phospholipid, a lipid, and a detergent. In one embodiment the lipid is a second phosphatidylcholine, wherein the first phosphatidylcholine and the second phosphatidylcholine differ in one or two fatty acid residues or fatty acid residue derivatives which are esterified to the glycerol backbone of the phosphatidylcholine. In one embodiment the apolipoprotein is selected from an apolipoprotein that has the amino acid sequence selected from SEQ ID NO: 01, 02, 06, 66, and 67, or is a variant thereof that has at least 70% sequence identity with the selected sequence.
    Type: Grant
    Filed: August 25, 2011
    Date of Patent: November 17, 2015
    Assignee: Hoffman—La Roche Inc.
    Inventors: Martin Bader, Monika Baehner, Juergen Fingerle, Ulrich Kohnert, Jean-Luc Mary, Silke Mohl
  • TETRANECTIN-APOLIPOPROTEIN A-I, LIPID PARTICLES CONTAINING IT AND ITS USE
    Publication number: 20120190610
    Abstract: A lipid particle comprising an apolipoprotein, a phosphatidylcholine and a lipid, such as a phospholipid, fatty acid or steroid lipid. In one embodiment the lipid particle comprises only one apolipoprotein. In one embodiment the lipid particle is consisting of one apolipoprotein, a phospholipid, a lipid, and a detergent. In one embodiment the lipid is a second phosphatidylcholine, wherein the first phosphatidylcholine and the second phosphatidylcholine differ in one or two fatty acid residues or fatty acid residue derivatives which are esterified to the glycerol backbone of the phosphatidylcholine. In one embodiment the apolipoprotein is selected from an apolipoprotein that has the amino acid sequence selected from SEQ ID NO: 01, 02, 06, 66, and 67, or is a variant thereof that has at least 70% sequence identity with the selected sequence.
    Type: Application
    Filed: August 25, 2011
    Publication date: July 26, 2012
    Inventors: Martin Bader, Monika Baehner, Juergen Fingerle, Ulrich Kohnert, Jean-Luc Mary, Silke Mohl
  • Guinea pig-chymase
    Publication number: 20070016970
    Abstract: The present invention relates to the sequence of guinea pig chymase. Since guinea pigs express only one chymase isoform, they are particularly suitable as a model for a method for identifying compounds that modulate chymase.
    Type: Application
    Filed: July 11, 2006
    Publication date: January 18, 2007
    Inventors: Juergen Fingerle, Jeremy Beauchamp
  • Modified phosphodiesterase polypeptides with altered physiochemical properties
    Publication number: 20050106581
    Abstract: Modified phosphodiesterase (PDE) polypeptides with altered physicochemical properties are disclosed, together with the polynucleotides encoding such modified PDE polypeptides, antibodies against such polypeptides and methods of preparation. Such polypeptides are useful for screening assays for identification of agonists or antagonists of phosphodiesterase activity.
    Type: Application
    Filed: December 15, 2003
    Publication date: May 19, 2005
    Inventors: Ulrich Certa, Juergen Fingerle, Peter Nelboeck-Hochstetter, Hans-Joachim Schoenfeld