Abstract: A process for the epoxidation of propene involves reacting propene with hydrogen peroxide, in the presence of a methanol solvent and a shaped titanium zeolite epoxidation catalyst in a fixed bed reactor. The process then involves recovering methanol from the reaction mixture, treatment of the recovered methanol by passing it through a bed of an acidic ion exchange resin, and recycling the treated methanol to the epoxidation reaction; as well as regeneration of the acidic ion exchange resin. Catalyst breakage can be reduced or avoided by washing the regenerated bed of an acidic ion exchange resin with methanol until the methanol exiting the resin bed has an apparent pH higher than 1.8, before methanol treated with the acidic ion exchange resin is recycled to the epoxidation reaction.

Abstract: The present invention relates to a method for starting a fuel cell stack at temperatures below the freezing point of a reaction product produced during the reaction between an anode-side fuel and a cathode-side fuel. The fuel cell stack comprises a plurality of individual cells having at least one internal cell which is arranged in the stacking direction in the interior of the fuel cell stack and an edge cell which is arranged in the stacking direction at the edge of the fuel cell stack. The fuel cell stack is connected to a cooling circuit having cooling fluid for cooling the fuel cell stack, which cooling fluid can be conducted through the fuel cell stack by a pump arranged in the cooling circuit.

Abstract: A subsea housing assembly has a subsea housing with a first and a second housing portion. The first and second housing portions have first and second electrical connections for data communication. A wall separates the first and second housing portions. The assembly has an inductive coupler with first and second coupling sections disposed in the first and second housing portions. The inductive coupler provides inductive coupling across the wall for data communication between the first and second electrical connections. The inductive coupler has inner and outer coils wherein the outer coil at least partly surrounds the inner coil and at least part of the wall extends between the inner and outer coil. Soft magnetic material is arranged around the outer coil and/or inside the inner coil such that the magnetic flux is collected and guided from the outer to the inner coil and/or from the inner to the outer coil.

Abstract: The present invention relates to antigen binding sites, compositions and uses thereof in the treatment of conditions associated with pathogenic proteins. In one example the condition is Alzheimer's disease.

Abstract: A device supplies energy to a sensor arrangement in a rail vehicle. The device has a housing in which there is arranged a coil which can be inductively coupled to a motor cable carrying an alternating current. The housing is embodied to enclose part of a length of the motor cable, and the coil is wound around an annular coil core which concentrically or substantially concentrically surrounds the motor cable. The housing has multiple parts including at least one first and one second housing part. The annular coil core is implemented in multiple parts and a first coil core part is arranged in the first housing part and a second coil core part is arranged in the second housing part. The housing is further embodied to mechanically secure the motor cable to a component of the rail vehicle and/or to mechanically connect the motor cable to a further motor cable.

Abstract: The present invention is directed to methods for treating neurodegenerative diseases and/or improving cognitive function, in particular those associated with protein oligomers, aggregates or deposits, using acoustic energy, such as ultrasound. An 5 example of such a neurodegenerative disease is Alzheimer's disease. The present invention provides a method of improving cognitive function and/or memory in an individual with impaired memory and/or executive function, the method including the steps of identifying a region of the brain of the individual to be treated with acoustic energy, applying a clinically safe level of acoustic energy to the region, thereby 10 saturating or substantially saturating the region with acoustic energy, thereby improving memory in the individual.

Abstract: The present invention relates to methods of restoring cognitive function in aged individuals that do not exhibit a clinically detectable neurodegenerative disease. In one aspect, the present invention provides a method of improving cognitive function in an aged individual that does not have a neurodegenerative disease characterized by aggregation of a pathological protein, the method comprising or consisting of: applying a clinically safe level of acoustic energy to sites within a region of the brain, thereby saturating or substantially saturating the region with acoustic energy, thereby improving cognitive function in the aged individual.

Abstract: The invention relates to tau, to antibodies and related fragments thereof for binding to tau, to production of said antibodies and fragments and to use of said antibodies and fragments for detection and therapy of various conditions, including tauopathies. The invention also relates to compositions comprising tau antibodies for binding to tau and their use in combination with acoustic energy.

Abstract: A subsea housing assembly has a subsea housing with a first and a second housing portion. The first and second housing portions have first and second electrical connections for data communication. A wall separates the first and second housing portions. The assembly has an inductive coupler with first and second coupling sections disposed in the first and second housing portions. The inductive coupler provides inductive coupling across the wall for data communication between the first and second electrical connections. The inductive coupler has inner and outer coils wherein the outer coil at least partly surrounds the inner coil and at least part of the wall extends between the inner and outer coil. Soft magnetic material is arranged around the outer coil and/or inside the inner coil such that the magnetic flux is collected and guided from the outer to the inner coil and/or from the inner to the outer coil.

Abstract: The present invention is directed to methods for treating neurodegenerative diseases and/or improving cognitive function, in particular those associated with protein oligomers, aggregates or deposits, using acoustic energy, such as ultrasound. An 5 example of such a neurodegenerative disease is Alzheimer's disease. The present invention provides a method of improving cognitive function and/or memory in an individual with impaired memory and/or executive function, the method including the steps of identifying a region of the brain of the individual to be treated with acoustic energy, applying a clinically safe level of acoustic energy to the region, thereby 10 saturating or substantially saturating the region with acoustic energy, thereby improving memory in the individual.

Abstract: A torque sensor arrangement including a contactless torque sensor, in which the torque sensor is arranged on an electrically operating linear carriage is provided. A distance sensor is also arranged on the linear carriage such that it allows the distance to the object of which the torque is to be determined to be measured.

Abstract: The invention relates to an assay for identifying compounds for the treatment of various diseases including those associated with excitotoxicity. The invention also relates to cell lines and constructs for use in an assay of the invention. The invention also relates to methods for determining whether a compound reduces excitotoxic signalling in a cell and whether a compound that inhibits binding of Tau to Fyn is likely to selectively reduce excitotoxic cell signalling. The invention also relates to a Tau protein adapted to form a detectable signal when the Tau protein is bound to a Fyn protein. The invention also relates to a Fyn protein adapted to form a detectable signal when the Fyn protein is bound to a Tau protein.

Abstract: A method and a device are provided for the efficient charging of a vehicle battery of an electric vehicle by a charging station of a group charging station. The connected vehicle battery, starting from an initial charge state, is charged in accordance with a calculated charge priority value until the charge state of the vehicle battery reaches a selectable charge state. The calculated charge priority values of the vehicle batteries connected at the same time to the charging stations of the group charging station determine which batteries will be charged within a charging interval.

Abstract: A method and a device are provided for the efficient charging of a vehicle battery of an electric vehicle by a charging station of a group charging station. The connected vehicle battery, starting from an initial charge state, is charged in accordance with a calculated charge priority value until the charge state of the vehicle battery reaches a selectable charge state. The calculated charge priority values of the vehicle batteries connected at the same time to the charging stations of the group charging station determine which batteries will be charged within a charging interval.

Abstract: The invention relates to a device (1) for applying liquid coating materials, particularly paints, onto an application surface (8), comprising an ejection system (11) for the coating material, wherein the coating material is fed to a displacement chamber (12), is applied in the displacement chamber (12) by means of a displacement element (13), is fed from the displacement chamber (12) to a throttle (26) in metered doses and is then forcefully ejected via the throttle opening (5) thereof against the application surface (8) in the form of droplets.

Abstract: A transducer arrangement for a nondestructive ultrasonic material testing system has a multiplicity of ultrasound transducers which can be moved linearly or swiveled along a trajectory curve. A multiplicity of ultrasound transducers can be aligned with a point of a specimen. If the size and the focal length of the transducers prohibit an annular or similar arrangement, the transducers are divided into smaller groups. They are then arranged so that every transducer passes over each desired focal point on the specimen during movement of the transducers along the trajectory curve.

Abstract: The present invention discloses a method and an in-vivo assay system useful for the identification and testing of modulating agents as well as for the validation of therapies of neurodegenerative diseases associated with the formation of neurofibrillary tangles, in particular Alzheimer's disease. The present invention is based on the surprising finding that injection of ?-amyloid A?42 fibrils into brains of P301L mutant tau transgenic mice caused several-fold increases in the numbers and an accelerated production of neurofibrillary tangles in cell bodies predominantly within the amygdala. The induced neurofibrillary tangles occurred as early as 18 days after A?42 injections and displayed striking features of neurofibrillary tangles of several human neurodegenerative diseases, particularly Alzheimer's disease.

Abstract: The invention relates to the distribution of printer paper via a housing flap of a printer, the housing flap being rotatably mounted about an axle by use of a hinge, and at least one central part of the hinge may be a printing paper opening having at least a width B.

Abstract: A housing is disclosed which may be used for a tachograph. The housing includes a battery holder and at least one fastening element arranged to fasten the battery holder to the housing. With the housing it is possible to mount a battery in an exchangeable manner while preventing the possibility of manipulating the components inside the housing during a changing of the battery. When the battery holder is mounted on the housing, the fastening element can only be accessed from the inside of the housing.

Abstract: The present invention relates to a navigational button including an actuating element which is displaceable at least in two directions and controls the navigation button. The present actuating element is arranged in a casing and performs an action on a communication element. A limitation element is disposed between the actuating element and the casing in such a way that it limits actuation efforts performed on the navigational button.