Abstract: According to one aspect of the presently disclosed subject there is provided a computerized method for scoring performance of a move of a trainee in a trainee frame input in relation to a move of a trainer in a trainer video wherein the trainer move includes at least one trainer keyframe. The method comprising obtaining a trainee frame input comprising a trainee move, the trainee move comprising a plurality of trainee frames, based on the at least one trainer keyframe, processing the plurality of trainee frames to provide a move performance score, indicative of the performance of the trainee move in relation to the trainer move, with respect to at least one aspect of the performance. In some examples, the aspects can be one of a similarity aspect, a timing aspect, or a motion dynamics aspect or a combination thereof.

Abstract: A device for tangential flow filtration of a fluid includes a filter unit having has a first fluid opening and a second fluid opening for the fluid, a filter element and a permeate opening to discharge a permeate filtered out of the fluid, a first flow connection to connect the first fluid opening to a reservoir for the fluid, a second flow connection to connect the second fluid opening to the reservoir for the fluid, a first pump in the first flow connection, and configured to convey the fluid from the reservoir to the filter unit :a third flow connection configured to enable a fluid communication between the first flow connection and the second flow connection, the third flow connection bypassing the filter unit, and a second pump configured to circulate the fluid through the third flow connection and the filter unit.

Abstract: According to one aspect of the presently disclosed subject there is provided a computerized method for scoring performance of a move of a trainee in a trainee frame input in relation to a move of a trainer in a trainer video wherein the trainer move includes at least one trainer keyframe. The method comprising obtaining a trainee frame input comprising a trainee move, the trainee move comprising a plurality of trainee frames, based on the at least one trainer keyframe, processing the plurality of trainee frames to provide a move performance score, indicative of the performance of the trainee move in relation to the trainer move, with respect to at least one aspect of the performance. In some examples, the aspects can be one of a similarity aspect, a timing aspect, or a motion dynamics aspect or a combination thereof.

Abstract: Fisher discriminant analysis is performed on data sets of typically developing (TD) individuals and data sets of autism spectrum disorder (ASD) individuals to produce a model that classifies TD individuals from ASD individuals. The ASD data sets include pre-treatment folate-dependent one-carbon metabolism (FOCM) and transsulfuration (TS) pathway metabolic profile data and post-treatment folate-dependent one-carbon metabolism (FOCM) and transsulfuration (TS) pathway metabolic profile data for patients receiving one or more ASD treatments. Changes in adaptive behavior are predicted by utilizing regression of changes in adaptive behavior and changes in biochemical measurements observed in the data sets. Thus, the system can be used to predict the effectiveness of a given course of treatment for an ASD patient based on measured metabolite data of that patient, or to predict the overall effectiveness of a clinical trial based on metabolite data for the trial participants.

Abstract: Provided herein are methods of obtaining and applying measurements of metabolites to diagnosing ASD in a subject, particularly children, with high specificity and sensitivity. The metabolites can be measured in urine, serum, and whole blood samples.

Abstract: Provided herein are methods of obtaining and applying measurements of metabolites to quantifying maternal risk of having a child with autism spectrum disorder (ASD), with high specificity and sensitivity.

Abstract: Provided herein are metabolites and methods of using the metabolites for diagnosing and treating Autism Spectrum Disorder (ASD) in a subject with a gastrointestinal problem, for determining a personalized treatment protocol for the subject, and for monitoring the therapeutic effect of an ASD treatment protocol in the subject being treated with the ASD treatment protocol.

Abstract: Fisher discriminant analysis is performed on data sets of typically developing (TD) individuals and data sets of autism spectrum disorder (ASD) individuals to produce a model that classifies TD individuals from ASD individuals. The ASD data sets include pre-treatment folate-dependent one-carbon metabolism (FOCM) and transsulfuration (TS) pathway metabolic profile data and post-treatment folate-dependent one-carbon metabolism (FOCM) and transsulfuration (TS) pathway metabolic profile data for patients receiving one or more ASD treatments. Changes in adaptive behavior are predicted by utilizing regression of changes in adaptive behavior and changes in biochemical measurements observed in the data sets. Thus, the system can be used to predict the effectiveness of a given course of treatment for an ASD patient based on measured metabolite data of that patient, or to predict the overall effectiveness of a clinical trial based on metabolite data for the trial participants.

Abstract: Computed tomography (CT) screening, diagnosis, or another image analysis tasks are performed using one or more networks and/or algorithms to either integrate complementary tomographic image reconstructions and radiomics or map tomographic raw data directly to diagnostic findings in the machine learning framework. One or more reconstruction networks are trained to reconstruct tomographic images from a training set of CT projection data. One or more radiomics networks are trained to extract features from the tomographic images and associated training diagnostic data. The networks/algorithms are integrated into an end-to-end network and trained. A set of tomographic data, e.g., CT projection data, and other relevant information from an individual is input to the end-to-end network, and a potential diagnosis for the individual based on the features extracted by the end-to-end network is produced.

Abstract: Computed tomography (CT) screening, diagnosis, or another image analysis tasks are performed using one or more networks and/or algorithms to either integrate complementary tomographic image reconstructions and radiomics or map tomographic raw data directly to diagnostic findings in the machine learning framework. One or more reconstruction networks are trained to reconstruct tomographic images from a training set of CT projection data. One or more radiomics networks are trained to extract features from the tomographic images and associated training diagnostic data. The networks/algorithms are integrated into an end-to-end network and trained. A set of tomographic data, e.g., CT projection data, and other relevant information from an individual is input to the end-to-end network, and a potential diagnosis for the individual based on the features extracted by the end-to-end network is produced.

Abstract: Methods and systems for detecting an autism state are disclosed. A plurality of data arrays are received, each including a plurality of values. Each of the plurality of values represent a concentration of a different metabolite. A score for each of the plurality of data arrays is calculated based on a relationship between the plurality of values of each of the respective plurality of data arrays. The score for each of the plurality of data arrays is classified into an autism class and a neurotypical class. A test score for a test data array is calculated based on a relationship between the plurality of test values and can then be grouped into one of the autism class and the neurotypical class. The system thus can use biomarkers identified in a metabolic pathway, such as abnormalities in folate-dependent one-carbon metabolism (FOCM) and transsulfuration (TS), to identify patients with a high likelihood of having autism.

Abstract: An underground permeability measuring apparatus includes an injection member formed as a lance to be introduced into the underground, having a cavity for guiding a fluid to at least one exit port, which preferably is arranged in the free end region of the injection member, through the injection member and the exit port into the underground surrounding the injection member is injectable. An injection member for introduction into an underground includes a cavity for guiding a fluid to at least one exit port, which preferably is arranged in the free end region of the injection member. The apparatus further includes a pressure-increasing device, through which the fluid is injectable by overpressure through the injection member and the exit port into the underground surrounding the injection member.

Abstract: The invention relates to an intelligent lighting device with multiple luminaires, which are at least partially coupled to each other with a wireless communication device. For this purpose, the luminaires preferably have communication modules with transmitter/receiver devices, via which the luminaires can communicate with each other. It is thereby provided that in accordance with the current operating mode of one of the luminaires at least one of the other luminaires can adopt a different predefined operating mode. Said luminaire can, for example upon the switching on of a luminaire or when one of the luminaires detects a person by means of a sensor device in the area of the luminaire, go into a working level with a predefined light intensity and the other luminaires located in the vicinity of said one luminaire go into a background illumination, i.e. in an illumination with a lower illumination level (background level).

Abstract: A gas turbine rotor for a gas turbine is provided. The gas turbine rotor includes a compressor rotor shaft, a turbine rotor shaft and a coupling device frictionally connecting the two rotor shafts, wherein the coupling device is designed in such a way that the friction connection also exists when the two rotor shafts are displaced relative to one another. In this case, the turbine rotor shaft is lengthened at the end facing the compressor rotor shaft in such a way that the turbine rotor shaft overlaps with the compressor rotor shaft in the axial direction and the coupling device connects this lengthened end of the turbine shaft to the compressor rotor shaft in the radial direction.

Abstract: An oil supply system for a stationary turbomachine is provided. A safe operation of the turbomachine is enabled even at ambient temperatures of up to 60° C. for a plurality of hours in a novel connection arrangement of the components of the oil supply system, such as the oil tank, pump a, and heat exchanger, as well as the pipeline system, without one of the components having to be designed for a further increased operating temperature. The oil tank has two regions stacked horizontally one above the other for storing the oil. The two regions are largely or completely separated from each other by a separating element.

Abstract: The invention relates to an intelligent lighting device with multiple luminaires, which are at least partially coupled to each other with a wireless communication device. For this purpose, the luminaires preferably have communication modules with transmitter/receiver devices, via which the luminaires can communicate with each other. It is thereby provided that in accordance with the current operating mode of one of the luminaires at least one of the other luminaires can adopt a different predefined operating mode. Said luminaire can, for example upon the switching on of a luminaire or when one of the luminaires detects a person by means of a sensor device in the area of the luminaire, go into a working level with a predefined light intensity and the other luminaires located in the vicinity of said one luminaire go into a background illumination, i.e. in an illumination with a lower illumination level (background level).

Abstract: A gas turbine rotor for a gas turbine is provided. The gas turbine rotor includes a compressor rotor shaft, a turbine rotor shaft and a coupling device frictionally connecting the two rotor shafts, wherein the coupling device is designed in such a way that the friction connection also exists when the two rotor shafts are displaced relative to one another. In this case, the turbine rotor shaft is lengthened at the end facing the compressor rotor shaft in such a way that said turbine rotor shaft overlaps with the compressor rotor shaft in the axial direction and the coupling device connects this lengthened end of the turbine shaft to the compressor rotor shaft in the radial direction.

Abstract: A blade wheel consisting of sheet metal for use in motor vehicle refrigerant pumps has blades that are cut out of a disk and pitched and base disk segments that lie adjacent to the blades and remain between the latter. The blade wheel is formed by at least two different blade wheel elements which are provided with cut out, pitched blades, are interconnected in a fixed manner and are arranged so that their respective base disk segments are offset in relation to one another, forming a gap therebetween, the elements thus forming a common bottom disk. A hub sleeve is provided in the center of one of these blade wheel elements (the hub disk), and the center of the other blade wheel element or elements (the bore disk or disks) is provided with a hub sleeve receiving bore, which can be pushed onto the casing of the hub sleeve.

Abstract: The invention relates to a rotary pump (1) including a rotor (3) arranged in a closed pump housing (2) which is in operative connection with a drive (5) for the pumping of a fluid (4), wherein an inlet opening (6) is provided at the pump housing (2) for the intake of the fluid (4) into the pump housing (2) and an outlet opening (7) is provided at the pump housing (2) for conveying the fluid (4) out of the pump housing into a storage container (8) which is at least partially filled with the fluid (4). In accordance with the invention the outlet opening (7) is arranged and designed at the pump housing in such a way that the fluid (4) can be conveyed out of the pump housing (2) through the outlet opening (7) to the storage container (8) directly and free of ducting. The invention further relates to a hydrodynamic mixer (100) with a rotary pump (1) in accordance with the invention and also to the use of the rotary pump (1) and of the hydrodynamic mixer (100) for the processing of a fluid (4).