Patents by Inventor Juergen Hoffmann

Juergen Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7474462
    Abstract: A microscope with a first and a second illumination light beam for illuminating a sample, wherein the first and/or the second illumination light beam evanescently illuminates the sample. For the purpose of CARS testing, the first illumination light beam can be a pump light beam, and the second illumination light beam can be a Stokes light beam. To increase resolution, the first illumination light beam can be an excitation light beam, and the second illumination light beam can be a stimulation light beam.
    Type: Grant
    Filed: May 1, 2006
    Date of Patent: January 6, 2009
    Assignee: Leica Microsystems CMS GmbH
    Inventors: Heinrich Ulrich, Werner Knebel, Kyra Moellmann, Juergen Hoffmann
  • Patent number: 7353654
    Abstract: A gas turbine unit and method of operation thereof are disclosed. A very quick and easily controllable augmentation or reduction of shaft power produced by the gas turbine unit, in particular of large gas turbine units exhibiting a pressure ratio larger than 15 bar, is achieved by providing at least one liquid droplet injection device on the upstream side of the compressor for injecting liquid into the stream of intake air. The injection device allows the addition of liquid mass flow in the form of liquid droplets corresponding to the desired increase of shaft power. The amount of water mass flow corresponding to the desired increase or decrease of shaft power output is added or reduced in a substantially stepless manner immediately within a time interval determined by design characteristics of the injection device. Water mass flow is preferentially injected substantially across the entire cross-section of the intake air guide.
    Type: Grant
    Filed: June 4, 2004
    Date of Patent: April 8, 2008
    Assignee: ALSTOM Technology Ltd
    Inventors: Giacomo Bolis, Gustav Hagström, Jürgen Hoffmann, Thorsten Wasmuth
  • Patent number: 7353656
    Abstract: A gas turbine unit and method of operation thereof are disclosed. A very quick and easily controllable augmentation or reduction of shaft power produced by the gas turbine unit, in particular of large gas turbine units exhibiting a pressure ratio larger than 15 bar, is achieved by providing at least one liquid droplet injection device on the upstream side of the compressor for injecting liquid into the stream of intake air. The injection device allows the addition of liquid mass flow in the form of liquid droplets corresponding to the desired increase of shaft power. The amount of water mass flow corresponding to the desired increase or decrease of shaft power output is added or reduced in a substantially stepless manner immediately within a time interval determined by design characteristics of the injection device. Water mass flow is preferentially injected substantially across the entire cross-section of the intake air guide.
    Type: Grant
    Filed: September 1, 2006
    Date of Patent: April 8, 2008
    Assignee: ALSTOM Technology Ltd
    Inventors: Giacomo Bolis, Gustav Hagström, Jürgen Hoffmann, Thorsten Wasmuth
  • Patent number: 7354905
    Abstract: There is provided compounds of formula I, R1O(O)C—CH2—(R)Cgl-Aze-Pab-R2I wherein R1 and R2 have meanings given in the description, which are useful as prodrugs of inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (eg thrombosis) or as anticoagulants.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: April 8, 2008
    Assignee: AstraZeneca AB
    Inventors: Thomas Antonsson, David Gustafsson, Kurt-Jürgen Hoffmann, Jan-Erik Nyström, Henrik Sörensen, Mikael Sellén
  • Patent number: 7353655
    Abstract: A gas turbine unit as well as a method for operating a gas turbine with high-pressure turbine and a low-pressure turbine unit are disclosed. A very quick and at the same time easily controllable augmentation or reduction of the shaft power of the gas turbine unit can be achieved by providing at least one liquid droplet injection device on the upstream side of said compressor for injecting liquid into the stream of intake air in order to increase the shaft power generated by the gas turbine unit. The amount of water mass flow corresponding to the desired increase or decrease of shaft power output of the gas turbine unit is added or reduced in the form of liquid droplets in a substantially stepless manner and immediately within a time interval that is determined by the design characteristics of the liquid droplet injection device.
    Type: Grant
    Filed: June 4, 2004
    Date of Patent: April 8, 2008
    Assignee: ALSTOM Technology Ltd
    Inventors: Giacomo Bolis, Gustav Hagström, Jürgen Hoffmann, Thorsten Wasmuth
  • Patent number: 7351821
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: April 1, 2008
    Assignee: AstraZeneca AB
    Inventors: Annika Björe, Magnus Björsne, David Cladingboel, Kurt-Jürgen Hoffmann, John Pavey, Fritiof Pontén, Gert Strandlund, Peder Svensson, Colin Thomson, Michael Wilsterman
  • Patent number: 7293415
    Abstract: In a method for operating a gas turbine centre in the vicinity of the group nominal full-load conditions, the cooling of the working fluid before and/or during the compression is set in such a way that the respectively attainable full-load power is above the current power. Rapid power demands can therefore be rapidly satisfied by an increase in the turbine inlet temperature or by opening an adjustable inlet guide vane row, whereas the control of the cooling effect, which has a tendency to be more sluggish, is employed to adjust the full-load operating point.
    Type: Grant
    Filed: August 11, 2005
    Date of Patent: November 13, 2007
    Assignee: ALSTOM Technology Ltd
    Inventors: Jürgen Hoffmann, Tom Alexander Odin McKay, Nikolaus Herbert Kurz, Tobias Spitzmüller
  • Publication number: 20070159690
    Abstract: A microscope with a first and a second illumination light beam for illuminating a sample, wherein the first and/or the second illumination light beam evanescently illuminates the sample. For the purpose of CARS testing, the first illumination light beam can be a pump light beam, and the second illumination light beam can be a Stokes light beam. To increase resolution, the first illumination light beam can be an excitation light beam, and the second illumination light beam can be a stimulation light beam.
    Type: Application
    Filed: May 1, 2006
    Publication date: July 12, 2007
    Applicant: Leica Microsystems CMS GmbH
    Inventors: Heinrich Ulrich, Werner Knebel, Kyra Moellmann, Juergen Hoffmann
  • Patent number: 7237386
    Abstract: A process is provided for the control of the amount of cooling air of a gas turbine set. Suitable means are provided in the cooling system to enable the amount of cooling air to be varied. The control of this means takes place in dependence on an operating parameter (X). This operating parameter is made dependent on the fuel type used.
    Type: Grant
    Filed: April 23, 2004
    Date of Patent: July 3, 2007
    Assignee: ALSTOM Technology Ltd
    Inventors: Jürgen Hoffmann, Stefan Rofka, René Wälchli
  • Publication number: 20060277916
    Abstract: A liquid atomizing arrangement comprises: a line system, at least one pressure atomizer nozzle, at least one line for the liquid to be atomized, and at least one first actuator for setting the atomizing supply pressure and/or the liquid mass flow through the atomizing arrangement. method of operating the liquid atomizing arrangement comprises the steps of measuring the mass flow flowing through the liquid atomizing arrangement, of measuring the atomizing supply pressure upstream of the pressure atomizer nozzle, and of acting upon the first actuator as a function of at least one of these measured values.
    Type: Application
    Filed: May 3, 2006
    Publication date: December 14, 2006
    Applicant: ALSTOM Technology Ltd
    Inventors: Juergen Hoffmann, Carlos Haertel, Sasha Savic
  • Patent number: 7143573
    Abstract: A gas turbine set, with a cooling air system through which at least one cooling air mass flow flows from a compressor to thermally highly loaded components of the gas turbine set. Pressure increasing ejectors are arranged in a cooling air duct of the cooling air system for increasing the pressure of flowing cooling air. The ejectors are operable with a working fluid. The working fluid mass flow is less than twenty percent of a driven cooling air mass flow.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: December 5, 2006
    Assignee: Alstom Switzerland Ltd
    Inventors: Juergen Hoffmann, Stefan Rofka, René Waelchli, Rolf Dittmann
  • Patent number: 7104071
    Abstract: A gas turbine group is provided with at least one cooling apparatus for cooling the working medium before and/or during the compression. The cooling power of the cooling apparatus can be adjusted by suitable means. A controller controls the cooling power of the cooling apparatus as a function of a control deviation in the useful power of the gas turbine group. The cooling controller interacts with other controllers of the gas turbine group in such a way that the gas turbine group is itself always operated at least close to its full load operating state. In this context, it is preferable for the inlet guide vane row of the compressor to be maximally open, and for the hot-gas temperature on entry into the turbines to be controlled so that it is constantly at an upper limit value.
    Type: Grant
    Filed: July 7, 2004
    Date of Patent: September 12, 2006
    Assignee: ALSTOM Technology Ltd
    Inventors: Jost Braun, Jürgen Hoffmann, Uwe Möller
  • Patent number: 7054062
    Abstract: The present invention concerns a double confocal scanning microscope (1) having an illuminating beam path (2) of at least one light source (3), and a detected beam path (4) of at least one detector (5), and in order to achieve almost the theoretically possible resolution capability, in particular in the context of multi-color fluorescence applications, is characterized in that the optical properties in particular of the components (6, 10, 13, 14) arranged in the beam path are coordinated with one another in such a way that the accumulated aberrations, with respect to the optical axis (33) and/or at least one surface (18, 19, 20) in the specimen region, are at least of the order of magnitude of the theoretically achievable resolution capability.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: May 30, 2006
    Assignee: Leica Microsystems Heidelberg GmbH
    Inventors: Johann Engelhardt, Jörg Bewersdorf, Hilmar Gugel, Juergen Hoffmann
  • Patent number: 7046154
    Abstract: The invention relates to a flame-monitoring device in which an a.c. input voltage (U1) is limited to a voltage limit (U2) by means of a voltage limiter (4). Said voltage limit (U2) is applied to a flame sensing device (7) which operates by means of the rectifying effect of a flame, and through which a current (i) flows, especially when a flame (6) is present. An asymmetric voltage limit (U2) can be defined by said voltage limiter (4), said limit being then applied to the sensing device (7).
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: May 16, 2006
    Assignee: Siemens Building Technologies AG
    Inventors: Klaus Bott, Alexander Diebold, Jürgen Hoffmann, Reiner Kind
  • Publication number: 20060091243
    Abstract: A silencer in a flow duct (10) comprises at least one plate-shaped element (12) which extends essentially parallel to the throughflow direction (16) of the flow duct. Integrated in the plate-shaped element (12), preferably in the downstream region, are means (13, 14) for feeding and for spraying a liquid (15) into the throughflow of the flow duct. The spraying means are preferably arranged in such a way that the liquid (15) is sprayed at an angle of at least 30° to the throughflow (16). The silencer according to the invention is used, for example, in the intake duct of a gas turboset.
    Type: Application
    Filed: November 9, 2005
    Publication date: May 4, 2006
    Applicant: ALSTOM Technology Ltd
    Inventor: Juergen Hoffmann
  • Publication number: 20060058585
    Abstract: A medical instrument system for creating a surgical operating space in the human or animal body by minimally invasive way in operations on the jaw comprises a shaft, which can be introduced through an incision in the cheek, and a plate-shaped flat element which can be introduced through the mouth, a connection mechanism being provided at a distal end of the shaft and on the plate-shaped element and being designed such that the plate-shaped element can be secured on the shaft.
    Type: Application
    Filed: September 6, 2005
    Publication date: March 16, 2006
    Inventors: Martin Oberlaender, Stefan Rehbein, Klaus Irion, Michael Sauer, Siegmar Reinert, Michael Krimmel, Eberhard Utz, Juergen Hoffmann
  • Patent number: 7012074
    Abstract: There is provided compounds of formula (I), wherein R1, R2 and Ra to Rb have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: October 18, 2001
    Date of Patent: March 14, 2006
    Assignee: AstraZeneca AB
    Inventors: Magnus Bjorsne, Kurt-Jürgen Hoffmann, Fritiof Pontén, Gert Strandlund, Peder Svensson, Michael Wilstermann
  • Patent number: 7009161
    Abstract: The scanning microscope includes an illumination beam path, microscope optics and at least one light source which generates an excitation light beam of a first wavelength and a second light beam of a second wavelength. Microscope optics are provided for focussing the excitation light beam onto a first focal region in a first plane of a sample and for focusing the second light beam onto a second focal region in a second plane of the sample. The first focal region and the second focal region overlap partially. The optical properties of the components arranged in the illumination beam path are matched to one another such that optical aberrations are corrected in such a way that the focal regions remain static relative to one another irrespective of the scanning movement.
    Type: Grant
    Filed: May 23, 2005
    Date of Patent: March 7, 2006
    Assignee: Leica Microsystems CMS GmbH
    Inventor: Juergen Hoffmann
  • Publication number: 20050279101
    Abstract: The injection of finely atomized liquid-droplets into the intake air flow of a compressor is used, for example, to improve the output of a gas turbine. If the atomization is effected via pressure atomizer nozzles, it is advantageous, when the injection device is operated with a portion of the design mass flow, to admit liquid to only some of the atomizer nozzles of the injection device. The atomizer nozzles may be arranged on nozzle tubes, liquid being jointly admitted to all the atomizer nozzles arranged on a respective nozzle tube, operated in such a way that the same mass flow is injected on each side of a symmetry line. To this end, nozzle tubes may be combined to form groups, to which liquid is jointly admitted, and the tubes of a group may be arranged in mirror image to one another relative to the symmetry line.
    Type: Application
    Filed: June 2, 2005
    Publication date: December 22, 2005
    Inventors: Juergen Hoffmann, Charles Matz
  • Patent number: 6961124
    Abstract: A method for examining a specimen (27) that exhibits at least two optical transition lines and is optically excitable at least with light of a first and light of a second wavelength is characterized by the step of illuminating the specimen (27) with illuminating light (15) that generates at least a multiple of the first wavelength and a multiple of the second wavelength; and by the step of detecting the detected light (29) proceeding from the specimen (27). Also disclosed is a scanning microscope system (1) having at least one light source (3) that emits illuminating light (15) for illumination of a specimen (27), the specimen (27) exhibiting at least two optical transition lines and being optically excitable at least with light of a first and light of a second wavelength, having at least one detector (41, 43, 65, 77, 79) for detection of the detected light (29) proceeding from the specimen (27) and an objective (25) for focusing the illuminating light (15) onto a subregion of the specimen (27).
    Type: Grant
    Filed: April 26, 2002
    Date of Patent: November 1, 2005
    Assignee: Leica Microsystems Heidelberg GmbH
    Inventors: Johann Engelhardt, Juergen Hoffmann