Patents by Inventor Juergen Michael Schanzer

Juergen Michael Schanzer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BISPECIFIC ANTI-VEGF/ANTI-ANG-2 ANTIBODIES
    Publication number: 20170369566
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: May 23, 2017
    Publication date: December 28, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas
  • BISPECIFIC, BIVALENT ANTI-VEGF/ANTI-ANG-2 ANTIBODIES
    Publication number: 20170240626
    Abstract: The present invention relates to bispecific, bivalent antibodies against human vascular endothelial growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: October 4, 2016
    Publication date: August 24, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Monika Baehner, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Kay-Gunnar Stubenrauch, Markus Thomas
  • Bispecific anti-VEGF/anti-ANG-2 antibodies
    Patent number: 9708396
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: July 18, 2017
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas
  • Bispecific antigen binding proteins
    Patent number: 9676845
    Abstract: The present invention relates to bispecific antigen binding proteins, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: May 17, 2010
    Date of Patent: June 13, 2017
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Sabine Imhof-Jung, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer
  • Bispecific anti-EGFR/anti IGF-1R antibodies
    Patent number: 9650442
    Abstract: The present invention relates to bispecific anti-EGFR/anti IGF-1R antibodies, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: May 16, 2017
    Assignee: Roche Glycart AG
    Inventors: Ralf Hosse, Christian Klein, Ekkehard Moessner, Juergen Michael Schanzer, Cuiying Shao, Lei Shi, Pablo Umana, Peng Wang, Katharina Wartha
  • BISPECIFIC HER2 ANTIBODIES AND METHODS OF USE
    Publication number: 20170029529
    Abstract: The present invention relates to bispecific HER2 antibodies, novel HER2 antibody variants, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: June 17, 2016
    Publication date: February 2, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Rebecca Croasdale, Lydia Jasmin Duerner, Guy Georges, Thomas Hofer, Ralf Hosse, Christian Klein, Ekkehard Moessner, Samuel Moser, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Claudio Sustmann, Pablo Umana
  • Multispecific antibodies comprising full length antibodies and single chain fab fragments
    Patent number: 9382323
    Abstract: The present invention relates to multispecific, especially bispecific antibodies comprising full length antibodies and single chain Fab fragments, methods for their production, pharmaceutical compositions containing the antibodies, and uses thereof.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: July 5, 2016
    Assignee: Roche Glycart AG
    Inventors: Ulrich Brinkmann, Peter Bruenker, Rebecca Croasdale, Christian Klein, Erhard Kopetzki, Ekkehard Moessner, Joerg Thomas Regula, Juergen Michael Schanzer, Jan Olaf Stracke, Pablo Umana
  • BISPECIFIC, BIVALENT ANTI-VEGF/ANTI-ANG2 ANTIBODIES
    Publication number: 20150191535
    Abstract: The present invention relates to bispecific, bivalent antibodies against human vascular endothelial growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: December 15, 2014
    Publication date: July 9, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Monika Baehner, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Kay-Gunnar Stubenrauch, Markus Thomas
  • BISPECIFIC, TETRAVALENT ANTIGEN BINDING PROTEINS
    Publication number: 20150044214
    Abstract: The present invention relates to bispecific, tetravalent antigen binding proteins, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: April 18, 2014
    Publication date: February 12, 2015
    Applicant: HOFFMANN-LA ROCHE, INC.
    Inventors: Sabine IMHOF-JUNG, Christian KLEIN, Joerg Thomas REGULA, Wolfgang SCHAEFER, Juergen Michael SCHANZER
  • TRI- OR TETRASPECIFIC ANTIBODIES
    Publication number: 20150030598
    Abstract: The present invention relates to tri- or tetraspecific antibodies, their manufacture and use.
    Type: Application
    Filed: June 25, 2014
    Publication date: January 29, 2015
    Inventors: Rebecca CROASDALE, Christian KLEIN, Wolfgang SCHAEFER, Juergen Michael SCHANZER
  • BISPECIFIC ANTI-VEGF/ANTI-ANG-2 ANTIBODIES
    Publication number: 20150004166
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: February 27, 2014
    Publication date: January 1, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas
  • Tri- or tetraspecific antibodies
    Patent number: 8796424
    Abstract: The present invention relates to tri- or tetraspecific antibodies, their manufacture and use.
    Type: Grant
    Filed: May 27, 2010
    Date of Patent: August 5, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Rebecca Croasdale, Christian Klein, Wolfgang Schaefer, Juergen Michael Schanzer
  • BISPECIFIC ANTI-EGFR/ANTI IGF-1R ANTIBODIES
    Publication number: 20140193415
    Abstract: The present invention relates to bispecific anti-EGFR/anti IGF-1R antibodies, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: March 20, 2014
    Publication date: July 10, 2014
    Applicant: ROCHE GLYCART AG
    Inventors: Ralf Hosse, Christian Klein, Ekkehard Moessner, Juergen Michael Schanzer, Cuiying Shao, Lei Shi, Pablo Umana, Peng Wang, Katharina Wartha
  • Bispecific Anti ErbB3 / Anti cMet Antibodies
    Publication number: 20140135482
    Abstract: The present invention relates to bispecific antibodies against human ErbB-3 and against human c-Met, methods for their production, pharmaceutical compositions containing the antibodies, and uses thereof.
    Type: Application
    Filed: January 16, 2014
    Publication date: May 15, 2014
    Applicant: ROCHE GLYCART AG
    Inventors: Birgit Bossenmaier, Ulrich Brinkmann, Wilma Dormeyer, Eike Hoffmann, Christian Klein, Gerhard Niederfellner, Juergen Michael Schanzer, Jan Olaf Stracke, Claudio Sustmann, Pablo Umana
  • Bispecific, tetravalent antigen binding proteins
    Patent number: 8703132
    Abstract: The present invention relates to bispecific, tetravalent antigen binding proteins, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: April 22, 2014
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Sabine Imhof-Jung, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer
  • Bispecific anti-VEGF/anti-ANG-2 antibodies
    Patent number: 8703130
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: August 9, 2012
    Date of Patent: April 22, 2014
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas
  • ACTIVATABLE BISPECIFIC ANTIBODIES
    Publication number: 20130266568
    Abstract: The current invention relates to bispecific antibodies wherein the binding affinity to one of the two antigens is reduced and which can be activated by tumor- or inflammation-specific proteases, and the preparation and use of such bispecific antibodies.
    Type: Application
    Filed: February 21, 2013
    Publication date: October 10, 2013
    Inventors: ULRICH BRINKMANN, REBECCA CROASDALE, SILKE METZ, JUERGEN MICHAEL SCHANZER, CLAUDIO SUSTMANN, PABLO UMANA
  • BISPECIFIC ANTIBODIES COMPRISING A DISULFIDE STABILIZED - FV FRAGMENT
    Publication number: 20130267686
    Abstract: The present invention relates to bispecific antibodies, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: February 21, 2013
    Publication date: October 10, 2013
    Inventors: ULRICH BRINKMANN, ALEXANDER HAAS, SILKE METZ, JUERGEN MICHAEL SCHANZER
  • TRIVALENT, BISPECIFIC ANTIBODIES
    Publication number: 20130022601
    Abstract: The present invention relates to trivalent, bispecific antibodies, methods for their production, pharmaceutical compositions containing the antibodies, and uses thereof.
    Type: Application
    Filed: August 7, 2012
    Publication date: January 24, 2013
    Inventors: Ulrich Brinkmann, Rebecca Croasdale, Eike Hoffmann, Christian Klein, Ekkehard Moessner, Juergen Michael Schanzer, Claudio Sustmann, Pablo Umana
  • BISPECIFIC ANTI-VEGF/ANTI-ANG-2 ANTIBODIES
    Publication number: 20120321627
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: August 9, 2012
    Publication date: December 20, 2012
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas