Patents by Inventor Juergen Mueller-Lehar

Juergen Mueller-Lehar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of N-amino substituted heterocyclic compounds
    Patent number: 7112682
    Abstract: An improved process for the preparation of N-amino nitrogen heterocyclic compounds is disclosed and claimed. In an embodiment of this invention, a compound of the formula (VI) is prepared starting from the corresponding indole derivative by way of N-amination and subsequently forming an hydrazone by the reaction with a keto compound in a single step. Further reduction of the hydrazone and subsequent coupling with a pyridine compound affords the compound of formula VI or a suitable salt thereof.
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: September 26, 2006
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Franz Weiberth, George Everett Lee, Reda G. Hanna, Juergen Mueller-Lehar, Silke Dubberke, Roland Utz
  • Process for preparing pyridine-substituted amino ketal derivatives
    Patent number: 6916934
    Abstract: The present invention relates to an efficient process for preparing derivatives of 1-(pyridinyl)-1,1-dialkoxy-2-aminoethane of the formula (I), with which compounds of the formula (I) can be prepared in high purity and yield and in the form of the free base without isolating the acetylpyridine oxime of the formula (XI) which is a critical product from a safety point of view as a solid.
    Type: Grant
    Filed: January 26, 2004
    Date of Patent: July 12, 2005
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Hans-Wolfram Flemming, Gerhard Korb, Juergen Mueller-Lehar, Walter Weber
  • Process for the preparation of N-amino substituted heterocyclic compounds
    Publication number: 20050101654
    Abstract: An improved process for the preparation of N-amino nitrogen heterocyclic compounds is disclosed and claimed. In an embodiment of this invention, a compound of the formula (VI) is prepared starting from the corresponding indole derivative by way of N-amination and subsequently forming an hydrazone by the reaction with a keto compound in a single step. Further reduction of the hydrazone and subsequent coupling with a pyridine compound affords the compound of formula VI or a suitable salt thereof.
    Type: Application
    Filed: October 1, 2004
    Publication date: May 12, 2005
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Franz Weiberth, George Lee, Reda Hanna, Juergen Mueller-Lehar, Silke Dubberke, Roland Utz
  • Process for preparing pyridine-substituted amino ketal derivatives
    Publication number: 20040158073
    Abstract: The present invention relates to an efficient process for preparing derivatives of 1-(pyridinyl)-1,1-dialkoxy-2-aminoethane of the formula (I), with which compounds of the formula (I) can be prepared in high purity and yield and in the form of the free base without isolating the acetylpyridine oxime of the formula (XI) which is a critical product from a safety point of view as a solid.
    Type: Application
    Filed: January 26, 2004
    Publication date: August 12, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Hans-Wolfram Flemming, Gerhard Korb, Juergen Mueller-Lehar, Walter Weber
  • Preparation of enamines in aqueous media
    Patent number: 5247091
    Abstract: The synthesis of enamines in aqueous media and a process for the preparation of memory enhancing 9-amino-1,2,3,4-tetrahydracridines are described.
    Type: Grant
    Filed: July 30, 1992
    Date of Patent: September 21, 1993
    Assignee: Hoechst Celanese Corporation
    Inventor: Juergen Mueller-Lehar