Patents by Inventor Juergen Roes

Juergen Roes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies against epitopes with homology to self antigens, methods of preparation
    Publication number: 20070101446
    Abstract: This invention provides novel methods of obtaining autologous monoclonal antibodies (AMABs) to self-antigens or homologs thereof. The method involves obtaining a genetically engineered host animal that does not biosynthesize at least one epitope of the antigen and utilizes the lack of self-tolerance of the host to the epitope to produce antibodies specific to the antigen. The invention also encompasses the AMABs produced by the methods. The invention further encompasses methods of isolating cells comprising the use of such AMABs that have specificity for a cell surface antigen.
    Type: Application
    Filed: October 10, 2006
    Publication date: May 3, 2007
    Applicant: Miltenyi Biotec GmbH
    Inventors: Klaus Rajewsky, Werner Mueller, Juergen Roes
  • Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof
    Patent number: 7119248
    Abstract: This invention provides novel methods of obtaining autologous monoclonal antibodies (AMABs) to self-antigens or homologs thereof. The method involves obtaining a genetically engineered host animal that does not biosynthesize at least one epitope of the antigen and utilizes the lack of self-tolerance of the host to the epitope to produce antibodies specific to the antigen. The invention also encompasses the AMABs produced by the methods. The invention further encompasses methods of isolating cells comprising the use of such AMABs that have specificity for a cell surface antigen.
    Type: Grant
    Filed: April 12, 1994
    Date of Patent: October 10, 2006
    Assignee: Miltenyi Biotec GmbH
    Inventors: Klaus Rajewsky, Werner Mueller, Juergen Roes