Abstract: The invention relates to a device for synchronizing a magnetic resonance unit with the cardiac rhythm of a patient, comprising a number of electrodes for leading off electrocardiogram signals from the body of the patient and an evaluation unit for determining a characteristic trigger time within a cardiac rhythm period of the patient from the electrocardiogram signals. In order to provide a device, which allows reliable determination of characteristic trigger times within the cardiac rhythm period of the patient even with elevated magnetic field strengths and which operates at least largely independently of external magnetic fields, it is proposed that the evaluation unit is designed to compare electrocardiogram signals obtained before and after the introduction of the patient into the magnetic resonance unit, in order to determine an enlargement of at least one characteristic of the electrocardiogram signals due to the magnetic field.

Abstract: The invention relates to a correction method for correcting interference due to gradient injections in ECG signal data records recorded in a magnetic resonance device by an ECG measuring device. A first correction data record is determined with the ECG measuring device located in a first position. A second correction data record is determined by the ECG measuring device located in a second position. An ECG signal data record is measured by the ECG measuring device located in a defined position. A modified correction data record is defined as a function of the first correction data record and the second correction data record and the first and second position and the defined position of the ECG measuring device. The ECG signal data record is corrected based on the modified correction data record.

Abstract: The invention relates to a method for checking ECG signals measured by an ECG measuring device having at least three electrodes for the presence of interference errors. At least three voltages are measured on a closed circulation path across the electrodes of the ECG measuring device. A monitoring value is calculated from the three measured voltages. A presence of an error is checked by determining a deviation of the monitoring value from a reference value. An error signal is outputted if an error is presented. The ECG measuring device has a further processing unit for processing voltage signals between a different pair of electrodes and a monitoring unit for calculating the monitoring value.

Abstract: An ECG measuring device and a magnetic resonance scanner to permit reliable detection of R-waves in ECG signals. The R-waves are identified by: measuring at least one reference ECG signal by an ECG measuring device, identifying an R-wave in the reference ECG signal, determining from the reference ECG signal at least one reference quantity which the reference ECG signal assumes in a time interval that starts before the R-wave of the ECG signal and lasts at a maximum up to the occurrence of the R-wave, generating at least one comparison rule on the basis of the at least one reference quantity, measuring ECG signals in which R-waves are to be identified, comparing the measured ECG signals with at least one reference quantity on the basis of the at least one comparison rule and outputting a trigger signal on the basis of at least one positive result of the comparison.

Abstract: The invention relates to a correction method for correction of noise resulting from gradient artifacts in ECG signal data records recorded in a magnetic resonance device by an ECG measuring apparatus. A first correction data record is determined with a reference point of the ECG measuring apparatus located at a first position in the magnetic resonance device. An ECG signal data record is measured with the reference point of the ECG measuring apparatus located at a second position in the magnetic resonance device. A modified correction data record is specified as a function of the first correction data record and the first and second position of the reference point. The ECG signal data record is corrected based on the modified correction data record.

Abstract: The invention relates to an arrangement for recording ECG signals. The arrangement has at least three electrodes, which can be connected or are connected to an amplification unit via lines, with at least two lines having no or essentially only a minimal distance from one another at least over one part of their length and being embodied as a component of a cable comprising more than two lines.

Abstract: This invention provides novel methods of obtaining autologous monoclonal antibodies (AMABs) to self-antigens or homologs thereof. The method involves obtaining a genetically engineered host animal that does not biosynthesize at least one epitope of the antigen and utilizes the lack of self-tolerance of the host to the epitope to produce antibodies specific to the antigen. The invention also encompasses the AMABs produced by the methods. The invention further encompasses methods of isolating cells comprising the use of such AMABs that have specificity for a cell surface antigen.

Abstract: This invention provides novel methods of obtaining autologous monoclonal antibodies (AMABs) to self-antigens or homologs thereof. The method involves obtaining a genetically engineered host animal that does not biosynthesize at least one epitope of the antigen and utilizes the lack of self-tolerance of the host to the epitope to produce antibodies specific to the antigen. The invention also encompasses the AMABs produced by the methods. The invention further encompasses methods of isolating cells comprising the use of such AMABs that have specificity for a cell surface antigen.