Abstract: In a method for the desorption of nucleic acids from a sample, in order to simplify the desorption of nucleic acids from the sample, a solid phase is repeatedly rinsed with an elution buffer in a microfluidic system, in order to elute nucleic acids bonded to the solid phase from the solid phase in the microfluidic system.

Abstract: A microfluidic device for analysing nucleic acids includes a pump unit with a pumping volume, a filter unit for receiving a lysate, and a reaction chamber. The pump unit, the filter unit and the reaction chamber are arranged in the stated order in a pump direction of the pump unit. The microfluidic device is configured to pump an elution medium via the pump unit into the filter unit for elution and subsequently into the reaction chamber for further treatment.

Abstract: A microfluidic device for analyzing samples includes at least two fluidic pathways for receiving samples and at least one capture area. The at least one capture area is configured for a detection unit for measuring light, and is configured to capture light emitted from samples in the at least two fluidic pathways, across the capture area.

Abstract: An apparatus to detect more than one analyte in a solution comprising at least one electrode in contact with the solution, at least two dyes including a first dye and a second dye, and an electrochemically active agent, where the solution has a pH, the electrode is configured to modulate the pH of the solution by oxidizing or reducing the electrochemically active agent, the first dye and the second dye fluoresce at different pH levels, fluorescence of the first dye is used to indicate the presence of a first analyte, and fluorescence of the second dye is used to indicate the presence of a second analyte. Methods of detecting multiple analytes in a solution are also provided.

Abstract: In a method for the desorption of nucleic acids from a sample, in order to simplify the desorption of nucleic acids from the sample, a solid phase is repeatedly rinsed with an elution buffer in a microfluidic system, in order to elute nucleic acids bonded to the solid phase from the solid phase in the microfluidic system.

Abstract: A microfluidic device for analysing nucleic acids includes a pump unit with a pumping volume, a filter unit for receiving a lysate, and a reaction chamber. The pump unit, the filter unit and the reaction chamber are arranged in the stated order in a pump direction of the pump unit. The microfluidic device is configured to pump an elution medium via the pump unit into the filter unit for elution and subsequently into the reaction chamber for further treatment.

Abstract: A microfluidic device for analyzing samples includes at least two fluidic pathways for receiving samples and at least one capture area. The at least one capture area is configured for a detection unit for measuring light, and is configured to capture light emitted from samples in the at least two fluidic pathways, across the capture area.

Abstract: An apparatus to detect more than one analyte in a solution comprising at least one electrode in contact with the solution, at least two dyes including a first dye and a second dye, and an electrochemically active agent, where the solution has a pH, the electrode is configured to modulate the pH of the solution by oxidizing or reducing the electrochemically active agent, the first dye and the second dye fluoresce at different pH levels, fluorescence of the first dye is used to indicate the presence of a first analyte, and fluorescence of the second dye is used to indicate the presence of a second analyte. Methods of detecting multiple analytes in a solution are also provided.

Abstract: A method for producing a pneumatically actuatable microfluidic analysis cartridge includes closing a joining side of a fluidic part of the analysis cartridge with a first fluid-tight elastic membrane and/or closing a joining side of a pneumatic part of the analysis cartridge with a second membrane. The fluidic part is configured to perform fluidic basic operations of a biochemical analysis process, and the pneumatic part is configured to control the basic operations using air pressure. The joining side of the fluidic part and the joining side of the pneumatic part are aligned, and the fluidic part and the pneumatic part are connected to form the analysis cartridge.

Abstract: A mixing chamber includes a container for receiving a first and a second component; an obstacle structure, which is designed such that, under the effect of a centrifugal force or magnetic force acting on the mixing chamber, it moves through the first and second components in the container and mixes them with each other; and a connection piece, which is connected at one end to the container and at the other end to the obstacle structure.

Abstract: A cartridge is configured for insertion and centrifugation in a centrifuge. The cartridge includes a mixing chamber, which comprises a container that is configured for at least one first component and at least one second component and electromagnetic particles. The electromagnetic particles are movable by an electromagnetic force to mix the first and second components.

Abstract: An analysis unit is configured to carry out a polymerase chain reaction. The analysis unit includes a lid element with at least one lid recess and a base element with at least one base recess. The base recess is arranged opposite the lid recess to form a reaction chamber. The analysis unit further includes a film arranged, at least in the region of the lid recess, between the lid element and the base element. The analysis unit also includes at least one channel formed between the lid element and the base element and configured to channel a fluid into and/or out of the base recess of the reaction chamber. The analysis unit includes a probe carrier arranged in the base recess and including at least one indicator material as the probe, for identifying a biochemical material. The indicator material on the probe carrier is in a solid aggregate state.

Abstract: A cartridge includes a first drum having a first chamber and a displacement device that is configured to rotate the first drum about a central axis to connect the first chamber to a second chamber in a conductive manner. The cartridge further includes an electric switch that is configured to be actuated by the displacement device between a closed switching state and an open switching state.

Abstract: A microfluidic system comprises a cartridge that includes a first drum which has a first chamber and an adjustment device which is arranged so as to rotate the first drum about its mid-axis and is configured to connect the first chamber conductively to a second chamber. The microfluidic system further comprises a pressure device which acts upon at least one component with a pressure difference and is configured to transfer the component between the first chamber and second chamber.

Abstract: A cartridge is configured for insertion and centrifugation in a centrifuge. The cartridge includes a first drum which has a first chamber, and a displacement device which is designed to rotate the first drum about a center axis thereof to selectively and conductively connect the first chamber to a second or a third chamber. In another embodiment, the cartridge includes a first drum which has a first chamber and a second chamber, and a displacement device which is designed to rotate the first drum about the center axis thereof to selectively and conductively connect the first chamber to a third chamber or the second chamber to the third chamber. The displacement device has an actuator which directly or indirectly moves the first drum about the center axis.

Abstract: A cartridge includes a drum that has at least one chamber and electrical contact elements, an adjusting device that is configured to rotate the drum about a center axis of the drum, and electrical conducting tracks on a housing of the cartridge. The electrical contact elements are brought into sliding contact with the electrical conducting tracks in order to transmit electrical energy.

Abstract: A revolver component for a reagent vessel for a centrifuge and/or for a pressure-varying device includes a revolver housing which is able to be installed in the reagent vessel. Provided on the revolver housing is a guide structure, which is able to be contacted using at least one elevation provided on one reagent vessel part of the reagent vessel or provided on a further revolver component. The guide structure is developed in such a way that the revolver housing is able to be adjusted, with respect to the at least contacted reagent vessel part or with respect to the further revolver component into a first submotion along an axis and into a second submotion about the axis.

Abstract: A revolver component for a reagent vessel has at least one first chamber that is configured to be filled at least partly with at least one liquid. The first chamber is formed or fitted such that a first chamber filling volume that is configured to be filled with the at least one liquid is delimited by an expansion-variable boundary. The expansion-variable boundary has a spatial expansion that can be reversibly adjusted such that the filling volume is configured to be varied. Reagent vessel insert parts and reagent vessels are also disclosed. Methods for centrifuging a material and for pressure treating a material are also disclosed.

Abstract: A centrifugable device for handling fluids includes at least two bodies that are arranged axially one above the other. The at least two bodies each have at least one cavity that is configured to be fluidically coupled to the at least one cavity of the other body. The device further includes at least one fluid path, the orientation of which fluid path runs in a manner dependent on an acting Coriolis force.

Abstract: A method for producing a pneumatically actuatable microfluidic analysis cartridge includes closing a joining side of a fluidic part of the analysis cartridge with a first fluid-tight elastic membrane and/or closing a joining side of a pneumatic part of the analysis cartridge with a second membrane. The fluidic part is configured to perform fluidic basic operations of a biochemical analysis process, and the pneumatic part is configured to control the basic operations using air pressure. The joining side of the fluidic part and the joining side of the pneumatic part are aligned, and the fluidic part and the pneumatic part are connected to form the analysis cartridge.