Patents by Inventor Juhani Lundell

Juhani Lundell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chromatographic purification of cyclosporing using a high pressure carbon dioxide eluent
    Patent number: 5976381
    Abstract: A process is provided for the preparation of pure cyclosporin which is purified chromatographically from a mixture of different cyclosporin forms and other substances prepared by fermentation. The process comprises feeding a mixture containing a desired form of cyclosporin with an eluent consisting of high pressure carbon dioxide and an adjuvant, into a chromatography column being packed with particles prepared of silica, and recovering from the eluent flow coming out of the chromatography column a fraction which contains the desired cyclosporin form in adequately pure form.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: November 2, 1999
    Assignee: Santen Oy
    Inventors: Juhani Lundell, Jarkko Ruohonen, Olli Aaltonen, Martti Alkio, Anneli Hase, Tapani Suortti
  • Process for producing immunosuppressives and a novel microbial species to be employed therein
    Patent number: 5409816
    Abstract: The invention relates to a process for producing a cyclosporin, especially cyclosporin A, by cultivating the strain (LEA3) of the novel Tolypocladium species aerobically at a temperature of 20.degree.-30 .degree. C. in a nutrient medium containing carbon sources, nitrogen sources and mineral salts, and, if desired, isolating and purifying the resulting cyclosporin.
    Type: Grant
    Filed: February 22, 1993
    Date of Patent: April 25, 1995
    Assignee: Leiras Oy
    Inventors: Juhani Lundell, Anja Kopio, Timo Korpela, Matti Ankelo