Patents by Inventor Juhani Luotola
Juhani Luotola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9694358Abstract: The present invention relates to a device and method for easy collection, dilution, mixing and dispensing of a liquid specimen in a self-contained system. The present invention can be used in combination with numerous testing means for performing chemical, biochemical or biomedical qualitative or quantitative assays in the field of both clinical and hygiene testing.Type: GrantFiled: March 27, 2009Date of Patent: July 4, 2017Assignee: ORION DIAGNOSTICA OYInventor: Juhani Luotola
-
Patent number: 9110027Abstract: The present invention relates to a method, device, and kit for analyzing a sample for determining the presence or amount of an analyte, particularly carbohydrate, more particularly sugar, in the sample using a fabric.Type: GrantFiled: November 28, 2012Date of Patent: August 18, 2015Assignee: Orion Diagnostica OyInventors: Juhani Luotola, Antti Sunnari, Terho Kololuoma, Mikko Keränen
-
Patent number: 8697006Abstract: A reagent or particles having reagent supported thereon are applied to a matrix material by a contact printing process for example in which the matrix material is brought into contact with a rotating contact roll having the reagent or particles having reagent supported thereon disposed thereon so as to transfer the reagent or particles having reagent supported thereon to the matrix material. Such a contact printing processes allow high speed and high volume production of an assay device.Type: GrantFiled: May 15, 2006Date of Patent: April 15, 2014Assignee: Orion Diagnostica OyInventors: Veli-Mies Häivä, Anna Kaisa Kylmä, Juhani Luotola
-
Patent number: 8662735Abstract: Sonication of a medium for example in an immunoassay is provided by applying sound waves from a transducer to a vessel in which the medium is held by a sonotrode coupled between the transducer and the vessel. The sonotrode has a recess in which the vessel is held, the recess being formed by facing surfaces of a plurality of protruding portions of the sonotrode separated by slits and arranged around the recess. The sonotrode is coupled to the vessel by dry contact with the vessel without any coupling layers therebetween. The use of such a sonotrode provides the advantages of allowing effective sonication with relatively low energy loss and with a low temperature elevation.Type: GrantFiled: November 13, 2012Date of Patent: March 4, 2014Assignee: Orion Diagnostica OyInventors: Juhani Luotola, Teuvo Sillanpaa
-
Publication number: 20130196444Abstract: The present invention relates to a method, device, and kit for analyzing a sample for determining the presence or amount of an analyte, particularly carbohydrate, more particularly sugar, in the sample using a fabric.Type: ApplicationFiled: November 28, 2012Publication date: August 1, 2013Inventors: Juhani Luotola, Antti Sunnari, Terho Kololuoma, Mikko Keränen
-
Patent number: 8377703Abstract: The present invention relates to a method, device and kit for analysing a sample for determining the presence or amount of an analyte, particularly carbohydrate, more particularly sugar, in the sample using a fabric.Type: GrantFiled: February 20, 2009Date of Patent: February 19, 2013Assignee: Orion Diagnostica OyInventors: Juhani Luotola, Antti Sunnari, Terho Kololuoma, Mikko Keränen
-
Patent number: 8342736Abstract: Sonication of a medium for example in an immunassay is provided by applying sound waves from a transducer to a vessel in which the medium is held by a sonotrode coupled between the transducer and the vessel. The sonotrode has a recess in which the vessel is held, the recess being formed by facing surfaces of a plurality of protruding portions of the sonotrode separated by slits and arranged around the recess. The sonotrode is coupled to the vessel by dry contact with the vessel without any coupling layers therebetween. The use of such a sonotrode provides the advantages of allowing effective sonication with relatively low energy loss and with a low temperature elevation.Type: GrantFiled: May 5, 2006Date of Patent: January 1, 2013Assignee: Orion Diagnostica OyInventors: Juhani Luotola, Teuvo Sillanpää
-
Publication number: 20110020195Abstract: The present invention relates to a device and method for easy collection, dilution, mixing and dispensing of a liquid specimen in a self-contained system. The present invention can be used in combination with numerous testing means for performing chemical, biochemical or biomedical qualitative or quantitative assays in the field of both clinical and hygiene testing.Type: ApplicationFiled: March 27, 2009Publication date: January 27, 2011Applicant: ORION DIAGNOSTICA OYInventor: Juhani Luotola
-
Publication number: 20100317123Abstract: The present invention relates to a method, device and kit for analysing a sample for determining the presence or amount of an analyte, particularly carbohydrate, more particularly sugar, in the sample using a fabric.Type: ApplicationFiled: February 20, 2009Publication date: December 16, 2010Applicant: Orion Diagnostica OyInventors: Juhani Luotola, Antti Sunnari, Terho Kololuoma, Mikko Keränen
-
Patent number: 7709212Abstract: The present invention provides a method for detecting the presence or amount of an analyte in a sample, said method comprising: a porous surface to which particles having attached thereto a binding substance, analyte and binding substance coated label particles are added. If said analyte is present in the sample an immuno- or chemical reaction occurs in the liquid phase. The separation of bound complex from unbound material is achieved by using said surface where the separation occurs mainly two dimensionally on the surface of the porous surface (e.g. grid). Interestingly, the disclosed surface enables a separation where said complexes are distributed two dimensionally on the porous surface (e.g. grid), whereas unbound materials are distributed three dimensionally. Accordingly, said surface enables both a two and a three dimensional separation.Type: GrantFiled: November 23, 2005Date of Patent: May 4, 2010Assignee: Orion Diagnostica OyInventors: Juhani Luotola, Hannu Nikula, Mira Murtovuori
-
Publication number: 20090215193Abstract: A reagent or particles having reagent supported thereon are applied to a matrix material by a contact printing process for example in which the matrix material is brought into contact with a rotating contact roll having the reagent or particles having reagent supported thereon disposed thereon so as to transfer the reagent or particles having reagent supported thereon to the matrix material. Such a contact printing processes allow high speed and high volume production of an assay device.Type: ApplicationFiled: May 15, 2006Publication date: August 27, 2009Applicant: ORION DIAGNOSTICA OYInventors: Veli-Mies Haiva, Anna Kaisa Kylma, Juhani Luotola
-
Patent number: 7534599Abstract: The present invention is directed to a growth medium support plate including an essential planar body part extending therefrom. The growth medium support plate also includes a stem member for connecting a cap to the support plate. The stem member is connected to the body part so as to have a position co-planar with the body part and a position inclined to the plane of the body part. The support plate includes at least one fixed projection extending from and co-planar with said body part adjacently to the stem member and the stem member having in the position coplanar with the body part a releasable connection to the at least one fixed projection.Type: GrantFiled: August 16, 2002Date of Patent: May 19, 2009Assignee: Orion Dianostica OyInventors: Henry Backman, Tapani Hellman, Antti Kaplas, Juhani Luotola, Jarmo Smolander
-
Publication number: 20080308404Abstract: Sonication of a medium for example in an immunoassay is provided by applying sound waves from a transducer to a vessel in which the medium is held via a sonotrode coupled between the transducer and the vessel. The sonotrode is coupled to the vessel by dry contact with the vessel without any coupling layers therebetween. The sonotrode which is operated in resonance has an arrangement with two protruding portions separated by a slit in the manner of a tuning fork with the vessel being mechanically held in a recess formed between the two protruding portions.Type: ApplicationFiled: May 5, 2006Publication date: December 18, 2008Applicant: Orion Diagnostica OYInventors: Juhani Luotola, Teuvo Sillanpaa
-
Publication number: 20080160537Abstract: The present invention provides a method for detecting the presence or amount of an analyte in a sample, said method comprising: a porous surface to which particles having attached thereto a binding substance, analyte and binding substance coated label particles are added. If said analyte is present in the sample an immuno- or chemical reaction occurs in the liquid phase. The separation of bound complex from unbound material is achieved by using said surface where the separation occurs mainly two dimensionally on the surface of the porous surface (e.g. grid). Interestingly, the disclosed surface enables a separation where said complexes are distributed two dimensionally on the porous surface (e.g. grid), whereas unbound materials are distributed three dimensionally. Accordingly, said surface enables both a two and a three dimensional separation.Type: ApplicationFiled: November 11, 2005Publication date: July 3, 2008Applicant: ORION DIAGNOSTICA OYInventors: Juhani Luotola, Hannu Nikula, Mira Murtovuori
-
Publication number: 20060121601Abstract: The present invention relates to a growth medium support plate (1) comprising a body part (13) and, situated essentially in the same plane therewith and extending therefrom, a stem member (8) for connecting a cap (10) to said support plate. The stem member is connected to the support plate so as to be flexible in regard to the plane of the support plate. The stem member is connected to the support plate body part in a flexurally stiff fashion.Type: ApplicationFiled: August 16, 2002Publication date: June 8, 2006Applicant: Orion-Yhtyma OyjInventors: Henry Backman, Tapani Hellman, Antti Kaplas, Juhani Luotola, Jarmo Smolander
-
Patent number: 6358753Abstract: The present invention relates to a method for binding antibody or antigen molecules to solid phase. The reactive compound comprising an antibody or antigen molecule and a solide phase are formed by coupling a specific antibody or antigen molecule to a solid phase using a two-step reaction. The coupling is covalent, between the active groups of the solid phase and the antibody, a fragment thereof or the antigen molecule, in the presence of an anionic surfactant, after adding an alkaline/solution to raise the pH to the basic region.Type: GrantFiled: June 16, 1999Date of Patent: March 19, 2002Assignee: Orion-Yhtymä OyjInventors: Juhani Luotola, Martti Malassu
-
Patent number: 6149866Abstract: The invention relates to a closure device and a method for performing an assay of a sample using the closure device. The closure device, mountable on the mouth of a test vessel, comprises a body part (1) with an axially passing cylindrical bore. The bore is covered at one end with an openable lid (7). The closure device further includes a plunger (3), slidably mounted in the bore for the formation of a sealed reagent storage chamber (9) in the space remaining between the closed lid and the plunger. The inner wall of the bore (2) is provided with at least one groove (4), whose depth is so deep as not to be within the reach of the outer diameter of the plunger (3). The groove extends from exterior end of the bore, over such a length as to maintain a gas flow communication between said reagent storage chamber (9) and the exterior end of the cylindrical bore when the plunger (3) is in a partially inserted position.Type: GrantFiled: February 19, 1998Date of Patent: November 21, 2000Assignee: Orion-yhtyma OyjInventors: Juhani Luotola, Henry Backman, Tapani Hellman, Kauko Kahma, Antti Kaplas