Abstract: Provided are a phenanthroline-based compound, a method of preparing the same, and a perovskite solar cell including the same. The phenanthroline-based compound may be formed as a uniform layer even by a solution process due to its low average surface roughness (root mean square, RMS) and excellent processability. When a layer having the phenanthroline-based compound is provided as a polymer functional layer of the perovskite solar cell, the ionic defects on the surface between the perovskite and a metal oxide, may be passivated and charge transfer may be facilitated so that the energy efficiency and photostability of the solar cell are improved.

Abstract: The present invention relates to a method for culturing a 3-dimensional lung cancer organoid and a method for preparing a patient-derived xenograft animal model using the same. More specifically, the present invention relates to a method for culturing a 3-dimensional lung cancer organoid, a lung cancer organoid prepared by the method, a medium composition for culturing the lung cancer organoid, a method for preparing a xenograft animal model using the lung cancer organoid, a patient-derived lung cancer organoid xenograft animal model prepared by the method, and a method for analyzing therapeutic efficacy of an anticancer agent and a method for screening an anticancer agent, using the animal model.

Abstract: A solvent removing apparatus includes a container containing an emulsion comprising a first raw material of a continuous phase and a second raw material of a dispersed phase, an impeller rotating in the container to stir the emulsion, and a foam breaker spaced apart from the impeller on an upper portion of the impeller, positioned below a surface of the emulsion to be submerged in the emulsion when the emulsion is calm, and rotating to reduce foam generated during stirring of the emulsion.

Abstract: A method for manufacturing a structure for microbe detection comprises the steps of: reacting nitrilotriacetic acid (NTA) and an acid anhydride to prepare a first compound; chelation of metal ions to the first compound to prepare a second compound; binding the second compound and a microbe detector to prepare a third compound; and mixing an exfoliated transition metal-dichalcogenide (TMD) compound and the third compound to prepare a structure for microbe detection, in which the metal ions of the third compound are bound with the transition metal-dichalcogenide compound.

Abstract: The present invention relates to microparticles comprising moxidectin and a biodegradable polymer, wherein the microparticles comprising moxidectin have a shape allowing a moxidectin drug to be uniformly distributed in spherical biodegradable polymer particles, and the average particle diameter of the microparticles is 80-130 ?m. The present invention relates to: extended release microparticles capable of continuously maintaining a heartworm disease prevention effect for 3 months to 6 months by administering microparticles comprising moxidectin; and a preparation method therefor. In addition, the present invention is prepared such that the average diameters of the particles have a predetermined micrometer size, and thus reduces a foreign body sensation and pain during administration into an animal through injection, thereby enabling administration through injection to be facilitated.

Abstract: Various example embodiments provide a transfer hand for transferring a substrate. The transfer hand for transferring the substrate comprises: a body; and a vacuum assembly installed in the body and providing decompression to the bottom surface of a substrate to support the substrate at the upper part of the body; wherein the vacuum assembly comprises: an vacuum pad with conductivity contacting the substrate; and a sealing member provided between the vacuum pad and the body, the sealing member electrically connected to the vacuum pad; wherein the sealing member is grounded.

Abstract: A display device includes a substrate having a first main display area, a second main display area, and a sub-display area positioned between the first main display area and the second main display area; a first driving circuit positioned on the sub-display area of the substrate; a first sub-pixel circuit and a second sub-pixel circuit positioned on respective sides of the first driving circuit in the sub-display area of the substrate; a first sub-light-emitting device connected to the first sub-pixel circuit and overlapping the first driving circuit; and a second sub-light-emitting device connected to the second sub-pixel circuit and overlapping the first driving circuit.

Abstract: Provided is a method for purifying an anti-4-1BB/anti-HER2 bispecific antibody, the method of which includes carrying out affinity chromatography with a sodium acetate buffer containing a certain inorganic salt as an elution buffer. The purification method of the presently claimed subject matter increases the elution of an antibody in the intact form, thereby being able to provide an anti-4-1BB/anti-HER2 bispecific antibody in the intact form in high purity and high yield.

Abstract: Provided are a method for preparing a polyetherketoneketone and a polyetherketoneketone prepared thereby, wherein, at the time of a polymerization reaction, nitrogen gas is blown into a liquid reaction medium while stirring, thereby quickly removing hydrochloric acid, which is a by-product generated during the reaction, and preventing aggregation of resin particles, thus suppressing the generation of scales.

Abstract: The present invention relates to: sustained-release microparticles capable of maintaining, for a long time, effects of preventing, treating or alleviating benign prostatic hyperplasia and prostate cancer and effects of preventing hair loss and promoting hair growth according to the administration of microparticles containing dutasteride; and a preparation method therefor, and according to the use of a method for administering the particles to a patient through an injection, a patient does not have to directly store or handle the microparticles, unlike an oral dosage form, and thus storage and handling are simple. In addition, drug effects are maintained for a long period of time of 1-3 months and, simultaneously, administration through injection can be facilitated since foreign body sensation and pain are reduced when being administered to a patient through injection because of the constant average diameter of the particles.

Abstract: A panel flattening assembly includes a first fixing assembly and a second fixing assembly respectively disposed at a first corner and a second corner adjacent to the first corner in a first direction on a rear surface of a display panel; a first supporting member disposed between the first fixing assembly and the second fixing assembly and spaced apart from the display panel; a first displacement adjusting member connected to the first fixing assembly and adjusting a distance between the first fixing assembly and a first end of the first supporting member by adjusting a displacement of the first fixing assembly; and a second displacement adjusting member connected to the second fixing assembly and adjusting a distance between the second fixing assembly and a second end of the first supporting member by adjusting a displacement of the second fixing assembly.

Abstract: A system for producing a microsphere includes a first raw material storing to store a first raw material is stored, a second raw material storing part to store a second raw material including a solvent, a biodegradable polymer, and a drug, an emulsion generating part to continuously form an emulsion including the first raw material of a continuous phase and the second raw material of a dispersed phase, a first solvent extracting and removing part to accommodate the emulsion formed from the emulsion generating part, and extract and remove the solvent from the dispersed phase of the emulsion to form a microsphere, and a second solvent extracting and removing part spaced apart from the first solvent extracting and removing part, to accommodate the emulsion formed from the emulsion generating part, and extract and remove the solvent from the dispersed phase of the emulsion to form a microsphere.

Abstract: One aspect provides a physiologically based pharmacokinetic core model which may be commonly applied to two or more compounds that share the same core structure, and a method of constructing the physiologically based pharmacokinetic core model. According to the physiologically based pharmacokinetic core model and the method of constructing the physiologically based pharmacokinetic core model, there is the effect of conducting exposure evaluation simply only by deriving a distribution coefficient, without constructing a separate PBPK model for each individual compound.

Abstract: Provided is an apparatus for a mass production of microspheres and a multichannel forming device incorporatable therein. The apparatus includes a multi-channel microsphere forming unit, a first source material reservoir containing the first source material and in fluid communication with the plurality of first microchannels, a second source material reservoir containing the second source material and in fluid communication with the plurality of second microchannels, a flow control unit configured to supply a first gas to the first source material reservoir at a first source material flow rate and to supply a second gas to a second source material reservoir at a second source material flow rate and a product reservoir for accommodating the microspheres formed from the multi-channel forming unit.

Abstract: A solvent-removing apparatus according to an embodiment includes a tank body accommodating an emulsion including first source material in a continuous phase and second source material in a dispersed phase, a fluid supply unit for supplying fluid into the tank body to cause the emulsion to circulate, and a discharge unit for discharging the gas in the tank body to the outside.

Abstract: A display device and a method of the manufacturing the display device is provided. The display device includes a substrate, a plurality of island pattern areas, a valley area partitioning the plurality of island pattern areas, a light emitting element emitting light, and a pixel driving part including a first subpixel driving part and a second subpixel driving part and supplying a driving current to the light emitting element. The plurality of island pattern areas include a first island pattern area in which the first subpixel driving part is disposed, and a second island pattern area in which the second subpixel driving part is disposed.

Abstract: The present disclosure provides a sustained formulation for prevention or treatment of autoimmune disease, comprising microparticles comprising naltrexone or pharmaceutically acceptable salts thereof, and biodegradable polymers, and a method using the same. Accordingly, it may be used to prevent or treat autoimmune diseases for a prolonged period of time with a single administration.

Abstract: A lipid nanoparticles manufacturing chip includes a mixer unit for forming a mixed solution by mixing a first raw material containing an active ingredient and a second raw material containing a lipid, a dilution unit that is connected to the mixer unit and dilutes the mixed solution using a diluent solution to make a diluted mixed solution, and a concentration unit connected to the dilution unit and for obtaining a concentrated solution by concentrating lipid nanoparticles (LNP) from the diluted mixed solution.

Abstract: A composition for sustained-release injection comprising deslorelin, can prevent initial over-release by adjusting the release rate of deslorelin at a target site and can exhibit the effect of deslorelin for 1 month or more by being exposed in an amount enough to show the effect of deslorelin. Further, the microparticles can prepare microparticles that have a uniform particle size and are capable of exhibiting the effect of continuously releasing deslorelin for a long time.

Abstract: A microparticle producing system using microfluidics and a controlling method thereof, and specifically, to a microparticle producing system that may stably transport droplets produced using microfluidics without agglomeration or destruction, compared to the conventional art, and a method of controlling the microparticle producing system to transport the droplets more stably in the microparticle producing system. By the microparticle producing system and the controlling method thereof, which are disclosed herein, droplets produced by the microparticle producing system using microfluidics may be stably transported without agglomeration or destruction, resulting in more effective microparticle production.