Patents by Inventor Jui-fen CHEN

Jui-fen CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11969450
    Abstract: Disclosed herein are methods for improving gastrointestinal barrier function, alleviating a gastrointestinal barrier dysfunction-associated disorder, and inhibiting growth of enteric pathogenic bacteria using a composition containing Lactobacillus rhamnosus MP108, Bifidobacterium longum subsp. infantis BLI-02, and Bifidobacterium animalis subsp. lactis BB-115, which are deposited at the China General Microbiological Culture Collection Center (CGMCC) respectively under accession numbers CGMCC 21225, CGMCC 15212, and CGMCC 21840. A number ratio of Lactobacillus rhamnosus MP108, Bifidobacterium longum subsp. infantis BLI-02, and Bifidobacterium animalis subsp. lactis BB-115 ranges from 1:0.2:0.67 to 1:9:9.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: April 30, 2024
    Assignee: GLAC BIOTECH CO., LTD.
    Inventors: Hsieh-Hsun Ho, Jui-Fen Chen, Yi-Wei Kuo, Chi-Huei Lin
  • Patent number: 11963987
    Abstract: At least one isolated lactic acid bacteria strains selected from the following: TSP05 (Lactobacillus plantarum), TSF331 (Lactobacillus fermentum) and TSR332 (Lactobacillus reuteri) is provided. The above-mentioned active or inactive lactic acid bacteria strains have a function of hepatoprotection and is used in a form of a food composition or a pharmaceutical composition.
    Type: Grant
    Filed: May 14, 2021
    Date of Patent: April 23, 2024
    Assignee: GLAC BIOTECH CO., LTD.
    Inventors: Hsieh-Hsun Ho, Yi Wei Kuo, Jui-Fen Chen, Ching-Wei Chen
  • Patent number: 11896632
    Abstract: Disclosed herein are methods for inhibiting growth of oral pathogenic bacteria and alleviating an oral pathogenic bacteria-associated disorder using a culture of at least one lactic acid bacterial strain selected from the group consisting of Lactobacillus rhamnosus MP108 which is deposited at the China General Microbiological Culture Collection Center (CGMCC) under an accession number CGMCC 21225, and Lactobacillus paracasei MP137 which is deposited at the CGMCC under an accession number CGMCC 21224.
    Type: Grant
    Filed: January 11, 2022
    Date of Patent: February 13, 2024
    Assignee: GLAC BIOTECH CO., LTD.
    Inventors: Hsieh-Hsun Ho, Yi-Wei Kuo, Ching-Wei Chen, Wen-Yang Lin, Jui-Fen Chen, Shu-Hui Chen
  • Patent number: 11865147
    Abstract: Disclosed herein are methods for reducing purine content in an edible material and alleviating a disorder of uric acid metabolism using Lactobacillus plantarum TSP05 which is deposited at the China General Microbiological Culture Collection Center (CGMCC) under an accession number CGMCC 16710.
    Type: Grant
    Filed: December 6, 2021
    Date of Patent: January 9, 2024
    Assignee: GLAC BIOTECH CO., LTD.
    Inventors: Hsieh-Hsun Ho, Ching-Wei Chen, Yi-Wei Kuo, Jui-Fen Chen
  • Publication number: 20230310523
    Abstract: The present invention discloses a method for maintaining or improving gastrointestinal condition, which includes: administering a lactic acid bacterial composition to a subject in need thereof, wherein the lactic acid bacterial composition comprises: a Lactobacillus paracasei ET-66 strain with a deposition number CGMCC 13514. The present invention also discloses a method for maintaining or improving gastrointestinal condition, which includes: administering a lactic acid bacterial fermentation composition to a subject in need thereof, wherein the lactic acid bacterial fermentation composition comprises: a fermentation product of a Lactobacillus paracasei ET-66 strain.
    Type: Application
    Filed: April 22, 2022
    Publication date: October 5, 2023
    Inventors: Hsieh-Hsun HO, Wen-Yang LIN, Jui-Fen CHEN, Yi-Wei KUO, Jia-Hung LIN, Chi-Huei LIN, Ching-Wei CHEN, Yu-Fen HUANG
  • Patent number: 11717546
    Abstract: The present invention provides a method for promoting defecation, comprising administering a composition which includes: a fermentation powder of lactic acid bacteria and a physiologically acceptable excipient, diluent, or carrier. The fermentation powder includes: a fermentation product of lactic acid bacteria, the fermentation product is obtained by incubating lactic acid bacterial strains in a culture medium containing milk, milk powders, casein, soy beans, bean products, or whey, and the lactic acid bacterial strains include: a Lactobacillus salivarius subsp. salicinius AP-32 strain, a Lactobacillus plantarum LPL28 strain, a Lactobacillus acidophilus TYCA06 strain, and a Bifidobacterium longum subsp. infantis BLI-02 strain.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: August 8, 2023
    Assignee: GLAC BIOTECH CO., LTD
    Inventors: Hsieh-Hsun Ho, Ching-Wei Chen, Yi-Wei Kuo, Yu-Fen Huang, Jui-Fen Chen, Cheng-Chi Lin
  • Publication number: 20230201280
    Abstract: Disclosed herein are methods for improving gastrointestinal barrier function, alleviating a gastrointestinal barrier dysfunction-associated disorder, and inhibiting growth of enteric pathogenic bacteria using a composition containing Lactobacillus rhamnosus MP108, Bifidobacterium longum subsp. infantis BLI-02, and Bifidobacterium animalis subsp. lactis BB-115, which are deposited at the China General Microbiological Culture Collection Center (CGMCC) respectively under accession numbers CGMCC 21225, CGMCC 15212, and CGMCC 21840. A number ratio of Lactobacillus rhamnosus MP108, Bifidobacterium longum subsp. infantis BLI-02, and Bifidobacterium animalis subsp. lactis BB-115 ranges from 1:0.2:0.67 to 1:9:9.
    Type: Application
    Filed: April 27, 2022
    Publication date: June 29, 2023
    Inventors: Hsieh-Hsun HO, Jui-Fen CHEN, Yi-Wei KUO, Chi-Huei LIN
  • Publication number: 20230100778
    Abstract: Disclosed herein is a method for promoting growth of a probiotic microorganism. The method includes cultivating the probiotic microorganism in a growth medium containing a fermented culture of lactic acid bacterial strains that include Lactobacillus salivarius subsp. salicinius AP-32 deposited at the China Center for Type Culture Collection (CCTCC) under CCTCC M 2011127, Lactobacillus plantarum LPL28 deposited at the China General Microbiological Culture Collection Center (CGMCC) under CGMCC 17954, Lactobacillus acidophilus TYCA06 deposited at the CGMCC under CGMCC 15210, and Bifidobacterium longum subsp. infantis BLI-02 deposited at the CGMCC under CGMCC 15212.
    Type: Application
    Filed: April 19, 2022
    Publication date: March 30, 2023
    Inventors: Hsieh-Hsun HO, Ching-Wei CHEN, Yu-Fen HUANG, Cheng-Chi LIN, Chen-Hung HSU, Tsai-Hsuan YI, Yu-Wen CHU, Yi-Wei KUO, Jui-Fen CHEN, Shin-Yu TSAI
  • Publication number: 20230036629
    Abstract: Disclosed herein are methods for inhibiting growth of oral pathogenic bacteria and alleviating an oral pathogenic bacteria-associated disorder using a culture of at least one lactic acid bacterial strain selected from the group consisting of Lactobacillus rhamnosus MP108 which is deposited at the China General Microbiological Culture Collection Center (CGMCC) under an accession number CGMCC 21225, and Lactobacillus paracasei MP137 which is deposited at the CGMCC under an accession number CGMCC 21224.
    Type: Application
    Filed: January 11, 2022
    Publication date: February 2, 2023
    Inventors: Hsieh-Hsun Ho, Yi-Wei Kuo, Ching-Wei Chen, Wen-Yang Lin, Jui-Fen Chen, Shu-Hui Chen
  • Publication number: 20230031534
    Abstract: Disclosed herein are methods for alleviating an enteric pathogenic bacterium-associated disorder and inhibiting growth of enteric pathogenic bacteria using a composition containing cultures of Lactobacillus rhamnosus MP108 which is deposited at the China General Microbiological Culture Collection Center (CGMCC) under an accession number CGMCC 21225, and Lactobacillus paracasei MP137 which is deposited at the CGMCC under an accession number CGMCC 21224.
    Type: Application
    Filed: January 11, 2022
    Publication date: February 2, 2023
    Inventors: Hsieh-Hsun HO, Yi-Wei Kuo, Ching-Wei Chen, Jui-Fen Chen, Shu-Hui Chen
  • Patent number: 11561308
    Abstract: A method for measuring radiation intensity includes measuring the radiation intensity received by the protein in a radiation field based on degree of protein degradation in the radiation field, wherein the degree of degradation is a ratio of the molecular weight of the protein before and after irradiation. The measuring method is simple in operation, small in number of steps, small in error, and capable of measuring radiation doses of various radiation fields or even mixed radiation fields. Use of a biological dosimeter for measuring the radiation intensity by the method in a neutron capture therapy system can not only assess radiation contamination in the irradiation chamber, but also evaluate the neutron dose.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: January 24, 2023
    Assignee: NEUBORON MEDTECH LTD.
    Inventors: Yuan-hao Liu, Jui-fen Chen, Jing He, Ming-chen Hsiao
  • Publication number: 20220313756
    Abstract: Disclosed herein is use of a culture of at least one lactic acid bacterial strain for alleviating a Helicobacter pylori-associated disorder. The at least one lactic acid bacterial strain is selected from the group consisting of Lactobacillus rhamnosus F-1 which is deposited at the China Center for Type Culture Collection (CCTCC) under an accession number CCTCC M 2011124, Lactobacillus plantarum LPL28 which is deposited at the China General Microbiological Culture Collection Center (CGMCC) under an accession number CGMCC 17954, and Lactobacillus acidophilus TYCA06 which is deposited at the CGMCC under an accession number CGMCC 15210.
    Type: Application
    Filed: October 1, 2021
    Publication date: October 6, 2022
    Inventors: Hsieh-Hsun HO, Ching-Wei CHEN, Yi-Wei KUO, Chi-Huei LIN, Jui-Fen CHEN
  • Publication number: 20220273734
    Abstract: Disclosed herein are methods for reducing purine content in an edible material and alleviating a disorder of uric acid metabolism using Lactobacillus plantarum TSP05 which is deposited at the China General Microbiological Culture Collection Center (CGMCC) under an accession number CGMCC 16710.
    Type: Application
    Filed: December 6, 2021
    Publication date: September 1, 2022
    Inventors: Hsieh-Hsun HO, Ching-Wei CHEN, Yi-Wei KUO, Jui-Fen CHEN
  • Publication number: 20210401908
    Abstract: The present invention provides a composition for promoting defecation, which includes: a fermentation powder of lactic acid bacteria and a physiologically acceptable excipient, diluent, or carrier. The fermentation powder includes: a fermentation product of lactic acid bacteria, the fermentation product is obtained by incubating lactic acid bacterial strains in a culture medium containing milk, milk powders, casein, soy beans, bean products, or whey, and the lactic acid bacterial strains include: a Lactobacillus salivarius subsp. salicinius AP-32 strain, a Lactobacillus plantarum LPL28 strain, a Lactobacillus acidophilus TYCA06 strain, and a Bifidobacterium longum subsp. infantis BLI-02 strain.
    Type: Application
    Filed: May 3, 2021
    Publication date: December 30, 2021
    Inventors: Hsieh-Hsun HO, Ching-Wei CHEN, Yi-Wei KUO, Yu-Fen HUANG, Jui-Fen CHEN, Cheng-Chi LIN
  • Publication number: 20210268048
    Abstract: At least one isolated lactic acid bacteria strains selected from the following: TSP05 (Lactobacillus plantarum), TSF331 (Lactobacillus fermentum) and TSR332 (Lactobacillus reuteri) is provided. The above-mentioned active or inactive lactic acid bacteria strains have a function of hepatoprotection and is used in a form of a food composition or a pharmaceutical composition.
    Type: Application
    Filed: May 14, 2021
    Publication date: September 2, 2021
    Inventors: Hsieh-Hsun HO, Yi Wei KUO, Jui- Fen CHEN, Ching-Wei CHEN
  • Patent number: 10709783
    Abstract: A neutron capture therapy system capable of eliminating amyloid ?-protein includes a neutron capture therapy device and a compound capable of specifically binding to the amyloid ?-protein having a nuclide with a large thermal neutron capture cross section. The neutron capture therapy device includes a neutron source, a beam shaping assembly and a collimator, the neutrons released by the neutron source pass through the beam shaping assembly and are slowed into a neutron beam within a certain energy range. The neutron beam irradiates the compound, and the energy generated by the reaction thereof can destroy the structure of the amyloid ?-protein. The neutron capture therapy system can specifically eliminate the amyloid ?-protein, and reduce the damage to the tissues surrounding the amyloid ?-protein.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: July 14, 2020
    Assignee: NEUBORON MEDTECH LTD.
    Inventors: Yuan-hao Liu, Jing He, Jui-fen Chen
  • Publication number: 20200003910
    Abstract: A method for measuring radiation intensity includes measuring the radiation intensity received by the protein in a radiation field based on degree of protein degradation in the radiation field, wherein the degree of degradation is a ratio of the molecular weight of the protein before and after irradiation. The measuring method is simple in operation, small in number of steps, small in error, and capable of measuring radiation doses of various radiation fields or even mixed radiation fields. Use of a biological dosimeter for measuring the radiation intensity by the method in a neutron capture therapy system can not only assess radiation contamination in the irradiation chamber, but also evaluate the neutron dose.
    Type: Application
    Filed: September 13, 2019
    Publication date: January 2, 2020
    Inventors: Yuan-hao LIU, Jui-fen CHEN, Jing HE, Ming-chen HSIAO
  • Publication number: 20190022222
    Abstract: The present disclosure provides a neutron capture therapy system for eliminating amyloid ?-protein deposition plaque, comprising a neutron capture therapy device and a 10B-containing compound capable of specifically binding to amyloid ?-protein deposition plaque, and the energy generated when the neutron beam generated by the neutron capture therapy device irradiates on the 10B element can destroy the structure of the amyloid ?-protein deposition plaque. The beneficial effects of the present disclosure are targeted and highly effective destruction of amyloid ?-protein deposition plaque.
    Type: Application
    Filed: September 27, 2018
    Publication date: January 24, 2019
    Inventors: Jui-fen CHEN, Jing HE, Yuan-hao LIU
  • Publication number: 20180360963
    Abstract: A neutron capture therapy system capable of eliminating amyloid ?-protein includes a neutron capture therapy device and a compound capable of specifically binding to the amyloid ?-protein having a nuclide with a large thermal neutron capture cross section. The neutron capture therapy device includes a neutron source, a beam shaping assembly and a collimator, the neutrons released by the neutron source pass through the beam shaping assembly and are slowed into a neutron beam within a certain energy range. The neutron beam irradiates the compound, and the energy generated by the reaction thereof can destroy the structure of the amyloid ?-protein. The neutron capture therapy system can specifically eliminate the amyloid ?-protein, and reduce the damage to the tissues surrounding the amyloid ?-protein.
    Type: Application
    Filed: June 18, 2018
    Publication date: December 20, 2018
    Inventors: Yuan-hao LIU, Jing HE, Jui-fen CHEN