Patents by Inventor Jui-Jen Chang

Jui-Jen Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250095762
    Abstract: A memory test circuit is provided. The memory test circuit is disposed in a memory array and including: a test array, including test cells out of memory cells of the memory array; a write multiplexer, configured to selectively output one of a test signal and a reference voltage based on a write measurement signal, wherein the test signal is output to write into at least one test cell and the reference voltage is output to a sense amplifier; and a read multiplexer, configured to selectively receive and output one of a readout signal corresponding to the test signal and an amplified signal based on a read measurement signal, wherein the readout signal is read from the at least one test cell and the amplified signal is obtained for a read margin evaluation from the sense amplifier by amplifying a voltage difference between the readout signal and the reference voltage.
    Type: Application
    Filed: November 27, 2024
    Publication date: March 20, 2025
    Applicant: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Jui-Jen Wu, Jen-Chieh Liu, Yi-Lun Lu, Win-San Khwa, Meng-Fan Chang
  • Publication number: 20250094125
    Abstract: A circuit includes local computing cells. Each of the local computing cells can provide, in response to identifying that the input data elements and weight data elements are in a first data type, a first sum including (i) a first product of a first input data element and a first weight data element; and (ii) a second product of a second input data element and a second weight data element. Each of the local computing cells can provide, in response to identifying that the input data elements and weight data elements are in a second data type, (i) a second sum of a first portion of a third input data element and a first portion of a third weight data element; and (ii) a third product of a second portion of the third input data element and a second portion of the third weight data element.
    Type: Application
    Filed: January 5, 2024
    Publication date: March 20, 2025
    Applicant: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Win-San Khwa, Jui-Jen Wu, Meng-Fan Chang, Ping-Chun Wu, Ho-Yu Chen
  • Publication number: 20250069627
    Abstract: A sense amplifier of a memory device that includes sense amplifier circuits and a reference sharing circuit is introduced. The sense amplifier circuits are configured to sense the plurality of bit lines according to an enable signal. The reference sharing circuit includes first switches and second switches that are coupled to the reference nodes and second reference nodes of the sense amplifier circuits, respectively. The first switches and second switches are controlled according to a control signal to control a first electrical connection among the first reference nodes, and to control a second electrical connection among the second reference nodes. An operation method of the sense amplifier and a memory device including the sense amplifier are also introduced.
    Type: Application
    Filed: November 5, 2024
    Publication date: February 27, 2025
    Applicant: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Win-San Khwa, Yen-Cheng Chiu, Yi-Lun Lu, Jui-Jen Wu, Meng-Fan Chang
  • Patent number: 12237009
    Abstract: The sense amplifier circuit includes a differential amplifier, a first switch, and a second switch. The differential amplifier includes a first input node, a second input node, a first output node, and a second output node. The differential amplifier amplifies a voltage difference of the first output node and the second output node according to a first input voltage of the first input node and a second input voltage of the second input node. A control node of the first (second) switch is coupled to a control line, the first (second) switch is coupled to the first (second) input node, and the first (second) switch is coupled to the first (second) output node. The first (second) switch pre-charges the first (second) input node by a first (second) output voltage of the first (second) output node while the control line is received a select signal.
    Type: Grant
    Filed: June 22, 2022
    Date of Patent: February 25, 2025
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Jui-Jen Wu, Jen-Chieh Liu, Yi-Lun Lu, Win-San Khwa, Meng-Fan Chang
  • Patent number: 12233159
    Abstract: The invention discloses an astaxanthin (AST) nanoemulsion and its manufacturing method. The manufacturing method comprising steps of: adding an AST material into a peanut oil and mixing them uniformly to obtain an AST oil; adding 0.25-1.5 (w/w) % of a surfactant into the AST oil and mixing them uniformly to obtain a mixed solution; and adding water into the mixed solution to obtain an AST emulsion precursor; and shaking the AST emulsion precursor to obtain the AST nanoemulsion.
    Type: Grant
    Filed: August 25, 2021
    Date of Patent: February 25, 2025
    Assignee: Trade Wind Biotech Co., Ltd.
    Inventors: Hui-Min Wang, Jui-Jen Chang, Hsing-Yu Huang, Yi-Chen Wang
  • Publication number: 20240016761
    Abstract: The present disclosure relates to a nutritional composition for inhibiting survival of an RNA virus and a method for treating an RNA virus infection. The nutritional composition consists of an astaxanthin extract and at least one probiotic extract. The at least one probiotic extract is selected from the group consisting of a lipoteichoic acid and a peptidoglycan. The method for treating the RNA virus infection includes administering an effective concentration of a nutritional composition to a subject in need thereof, wherein the nutritional composition consists of an astaxanthin extract and at least one probiotic extract, and the at least one probiotic extract is selected from the group consisting of a lipoteichoic acid and a peptidoglycan.
    Type: Application
    Filed: July 11, 2023
    Publication date: January 18, 2024
    Inventors: Jui-Jen Chang, Yeh Chen
  • Patent number: 11858965
    Abstract: The present disclosure relates to a recombinant protein comprising a plurality of type II cohesin repeats. The present disclosure provides a recombinant cellulosome complex comprising: the recombinant protein comprising a plurality of type II cohesin repeats; a recombinant cellulosome complex integrating protein A comprising a plurality of type I cohesin repeats, a plurality of cellulose-binding modules and a type II dockerin; and a plurality of recombinant enzymes each comprising a type I dockerin. A cell, a method for digesting a cellulose and a method for producing ethanol are also provided.
    Type: Grant
    Filed: May 21, 2021
    Date of Patent: January 2, 2024
    Assignee: ACADEMIA SINICA
    Inventors: Wen-Hsiung Li, Anandharaj Marimuthu, Jui-Jen Chang, Yu-Ju Lin, Rizwana Parveen Rani Mohamed Gobil, Chieh-Chen Huang
  • Patent number: 11781124
    Abstract: Disclosed herein are recombinant polynucleotide sequences, vectors, host cells and methods for producing astaxanthin. The recombinant polynucleotide sequence is designed to provide a higher level of astaxanthin precursors via a shorter metabolic pathway, and thereby attains higher level of end products (e.g., astaxanthin) with desired stereoisomeric form and/or esterified form.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: October 10, 2023
    Assignee: ACADEMIA SINICA
    Inventors: Jui-Jen Chang, Caroline Thia, Hao-Yeh Lin, Yu-Ju Lin, Chieh-Chen Huang, Wen-Hsiung Li
  • Publication number: 20230235370
    Abstract: A method for biosynthesis polyhydroxybutyrate by a yeast transformant of the invention includes the following steps: (1) transforming a polyhydroxybutyrate biosynthesis related gene into an oleaginous yeast to obtain an yeast transformant. (2) screening the yeast transformant. (3) cultivating the yeast transformant to obtain the polyhydroxybutyrate. The method of the invention provides a way of cheaper, faster and flexibility in biotechnology metabolism to improve PHB production.
    Type: Application
    Filed: January 25, 2022
    Publication date: July 27, 2023
    Inventor: JUI-JEN CHANG
  • Publication number: 20230061072
    Abstract: The invention discloses an astaxanthin (AST) nanoemulsion and its manufacturing method. The manufacturing method comprising steps of: adding an AST material into a peanut oil and mixing them uniformly to obtain an AST oil; adding 0.25-1.5 (w/w)% of a surfactant into the AST oil and mixing them uniformly to obtain a mixed solution; and adding water into the mixed solution to obtain an AST emulsion precursor; and shaking the AST emulsion precursor to obtain the AST nanoemulsion.
    Type: Application
    Filed: August 25, 2021
    Publication date: March 2, 2023
    Inventors: HUI-MIN WANG, JUI-JEN CHANG, HSING-YU HUANG, YI-CHEN WANG
  • Publication number: 20210363196
    Abstract: The present disclosure relates to a recombinant protein comprising a plurality of type II cohesin repeats. The present disclosure provides a recombinant cellulosome complex comprising: the recombinant protein comprising a plurality of type II cohesin repeats; a recombinant cellulosome complex integrating protein A comprising a plurality of type I cohesin repeats, a plurality of cellulose-binding modules and a type II dockerin; and a plurality of recombinant enzymes each comprising a type I dockerin. A cell, a method for digesting a cellulose and a method for producing ethanol are also provided.
    Type: Application
    Filed: May 21, 2021
    Publication date: November 25, 2021
    Inventors: Wen-Hsiung LI, Anandharaj MARIMUTHU, Jui-Jen CHANG, Yu-Ju LIN, Rizwana Parveen Rani MOHAMED GOBIL, Chieh-Chen HUANG
  • Publication number: 20210071153
    Abstract: Disclosed herein are recombinant polynucleotide sequences, vectors, host cells and methods for producing astaxanthin. The recombinant polynucleotide sequence is designed to provide a higher level of astaxanthin precursors via a shorter metabolic pathway, and thereby attains higher level of end products (e.g., astaxanthin) with desired stereoisomeric form and/or esterified form.
    Type: Application
    Filed: November 10, 2020
    Publication date: March 11, 2021
    Inventors: Jui-Jen CHANG, CAROLINE THIA, HAO-YEH LIN, YU-JU LIN, CHIEH-CHEN HUANG, WEN-HSIUNG LI
  • Patent number: 10865397
    Abstract: Disclosed herein are recombinant polynucleotide sequences, vectors, host cells and methods for producing astaxanthin. The recombinant polynucleotide sequence is designed to provide a higher level of astaxanthin precursors via a shorter metabolic pathway, and thereby attains higher level of end products (e.g., astaxanthin) with desired stereoisomeric form and/or esterified form.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: December 15, 2020
    Assignee: ACADEMIA SINICA
    Inventors: Jui-Jen Chang, Caroline Thia, Hao-Yeh Lin, Yu-Ju Lin, Chieh-Chen Huang, Wen-Hsiung Li
  • Publication number: 20190144841
    Abstract: Disclosed herein are recombinant polynucleotide sequences, vectors, host cells and methods for producing astaxanthin. The recombinant polynucleotide sequence is designed to provide a higher level of astaxanthin precursors via a shorter metabolic pathway, and thereby attains higher level of end products (e.g., astaxanthin) with desired stereoisomeric form and/or esterified form.
    Type: Application
    Filed: November 26, 2018
    Publication date: May 16, 2019
    Inventors: Jui-Jen CHANG, Caroline THIA, Hao-Yeh LIN, Yu-Ju LIN, Chieh-Chen HUANG, Wen-Hsiung LI
  • Patent number: 10087450
    Abstract: Described herein is an engineered Kluyveromyces marxianus cell, the cell comprising in its genome: (i) two different nucleic acid molecules that each contain a promoter operably linked to a gene encoding a functional enzyme, and (ii) a selection nucleic acid molecule that contains a promoter operably linked to a gene encoding a selectable marker, wherein all of the nucleic acids molecules of (i) and (ii) are in tandem and the engineered cell expresses all of the proteins encoded by the genes of (i) and (ii).
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: October 2, 2018
    Assignee: Academia Sinica
    Inventors: Jui-Jen Chang, Wen-Hsiung Li, Chieh-Chen Huang, Hao-Yeh Lin, Ming-Che Shih
  • Publication number: 20170137792
    Abstract: Disclosed herein are recombinant polynucleotide sequences, vectors, host cells and methods for producing astaxanthin. The recombinant polynucleotide sequence is designed to provide a higher level of astaxanthin precursors via a shorter metabolic pathway, and thereby attains higher level of end products (e.g., astaxanthin) with desired stereoisomeric form and/or esterified form.
    Type: Application
    Filed: November 16, 2016
    Publication date: May 18, 2017
    Inventors: Jui-Jen CHANG, Caroline THIA, Hao-Yeh LIN, Yu-Ju LIN, Chieh-Chen HUANG, Wen-Hsiung LI
  • Publication number: 20160251663
    Abstract: Described herein is an engineered Kluyveromyces marxianus cell, the cell comprising in its genome: (i) two different nucleic acid molecules that each contain a promoter operably linked to a gene encoding a functional enzyme, and (ii) a selection nucleic acid molecule that contains a promoter operably linked to a gene encoding a selectable marker, wherein all of the nucleic acids molecules of (i) and (ii) are in tandem and the engineered cell expresses all of the proteins encoded by the genes of (i) and (ii).
    Type: Application
    Filed: May 17, 2016
    Publication date: September 1, 2016
    Inventors: Jui-Jen Chang, Wen-Hsiung Li, Chieh-Chen Huang, Hao-Yeh Lin, Ming-Che Shih
  • Patent number: 9340794
    Abstract: Described is a method of introducing multiple nucleic acid molecules into the genome of a cell. The method includes providing a plurality of nucleic acid molecules, each of the plurality of nucleic acid molecules containing (a) a nucleic acid sequence operatively linked to a promoter sequence at the 5? end of the nucleic acid molecule, and (b) an overlapping sequence at the 3? end of the nucleic acid molecule.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: May 17, 2016
    Assignee: Academia Sinica
    Inventors: Jui-Jen Chang, Feng-Ju Ho, Cheng-Yu Ho, Wen-Hsiung Li, Ming-Che Shih, Chieh-Chen Huang
  • Publication number: 20140248703
    Abstract: Described is a method of introducing multiple nucleic acid molecules into the genome of a cell. The method includes providing a plurality of nucleic acid molecules, each of the plurality of nucleic acid molecules containing (a) a nucleic acid sequence operatively linked to a promoter sequence at the 5? end of the nucleic acid molecule, and (b) an overlapping sequence at the 3? end of the nucleic acid molecule.
    Type: Application
    Filed: August 31, 2012
    Publication date: September 4, 2014
    Applicant: Academia Sinica
    Inventors: Jui-Jen Chang, Feng-Ju Ho, Cheng-Yu Ho, Wen-Hsiung Li, Ming-Che Shih, Chieh-Chen Huang
  • Patent number: 8703474
    Abstract: Disclosed are a novel flavor compound-producing yeast strain and methods of using the strain to produce flavor compounds.
    Type: Grant
    Filed: August 16, 2011
    Date of Patent: April 22, 2014
    Assignee: Academia Sinica
    Inventors: Jui-Jen Chang, Cheng-Yu Ho, Chieh-Chen Huang, Ming-Che Shih, Wen-Hsiung Li