Patents by Inventor Jui-Lan Su

Jui-Lan Su has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMPOUNDS
    Publication number: 20110105724
    Abstract: The present invention relates to neutralizing antibodies (immunoglobulins) which are specific for human IL-8 and bind to as well as neutralize human IL-8.
    Type: Application
    Filed: August 15, 2008
    Publication date: May 5, 2011
    Inventors: Stephanie Jane Clegg, Jonathan H. Ellis, Paul Andrew Hamblin, Karen Fran Kozarsky, Jui-Lan Su, Deborah Ann Welham
  • Superficial zone protein-binding molecules and uses thereof
    Publication number: 20050089881
    Abstract: The invention provides an antibody or a fragment thereof having specific binding affinity for superficial zone protein (SZP) or a variant, fragment, or protein core thereof, wherein the binding affinity of the antibody or fragment thereof for human superficial zone protein is the same or greater than the binding affinity for bovine superficial zone protein in a competitive binding assay, IAsys analysis, or BIAcore analysis. The present invention further provides hybidoma cells that produce the monoclonal antibody and antibody reagent kits comprising the antibody or fragment of the invention. Further provided by the invention are methods of SZP detection, methods of diagnosing a degenerative joint condition, and screening methods related to the use of the antibody or fragment thereof.
    Type: Application
    Filed: February 17, 2004
    Publication date: April 28, 2005
    Inventors: Jeff Hutchins, Klaus Kuettner, Kathryn Lindley, Thomas Schmid, Barbara Schumacher, Stephen Stimpson, Jui-Lan Su
  • Superficial zone protein-binding molecules and uses thereof
    Patent number: 6720156
    Abstract: The invention provides an antibody or a fragment thereof having specific binding affinity for superficial zone protein (SZP) or a variant, fragment, or protein core thereof, wherein the binding affinity of the antibody or fragment thereof for human superficial zone protein is the same or greater than the binding affinity for bovine superficial zone protein in a competitive binding assay, IAsys analysis, or BIAcore analysis. The present invention further provides hybidoma cells that produce the monoclonal antibody and antibody reagent kits comprising the antibody or fragment of the invention. Further provided by the invention are methods of SZP detection, methods of diagnosing a degenerative joint condition, and screening methods related to the use of the antibody or fragment thereof.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: April 13, 2004
    Assignees: SmithKline Beecham Corporation, Rush-Presbyterian St Luke's Medical Center
    Inventors: Jeff T. Hutchins, Klaus E. Kuettner, Kathryn Mason Lindley, Thomas M. Schmid, Barbara L. Schumacher, Stephen Anthony Stimpson, Jui-Lan Su
  • Superficial zone protein and methods of making and using same
    Publication number: 20030180948
    Abstract: The present invention relates to SZP polypeptides and nucleic acids encoding the polypeptides. The invention further relates to methods of making and using the polypeptides and nucleic acids. Also, the invention relates to immortalized chondrocytes or SZP-producing cells and methods of using the cells. The invention also relates to a method of culturing immortalized or non-immortalized chondrocytes in serum-free medium. The invention also relates to a method of imaging an articular surface or synovium of a joint using detectably tagged SZP or detectably tagged SZP binding proteins.
    Type: Application
    Filed: December 31, 2001
    Publication date: September 25, 2003
    Inventors: Jeff T. Hutchins, Klaus E. Kuettner, Thomas M. Schmid, Barbara L. Schumacher, Jui-Lan Su, Eric P. Dixon
  • Superficial zone protein-binding molecules and uses thereof
    Publication number: 20020009761
    Abstract: The invention provides an antibody or a fragment thereof having specific binding affinity for superficial zone protein (SZP) or a variant, fragment, or protein core thereof, wherein the binding affinity of the antibody or fragment thereof for human superficial zone protein is the same or greater than the binding affinity for bovine superficial zone protein in a competitive binding assay, IAsys analysis, or BlAcore analysis. The present invention further provides hybidoma cells that produce the monoclonal antibody and antibody reagent kits comprising the antibody or fragment of the invention. Further provided by the invention are methods of SZP detection, methods of diagnosing a degenerative joint condition, and screening methods related to the use of the antibody or fragment thereof.
    Type: Application
    Filed: February 9, 2001
    Publication date: January 24, 2002
    Inventors: Jeff T. Hutchins, Klaus E. Kuettner, Kathryn Mason Lindley, Thomas M. Schmid, Barbara L. Schumacher, Stephen Anthony Stimpson, Jui-Lan Su