Patents by Inventor Julang Li

Julang Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing porcine fibroblasts with both CD163 gene and CD13 gene being knocked-out
    Patent number: 11240997
    Abstract: Provided is a double-gene knockout vector system, a method for preparing porcine fibroblasts with both CD163 gene and CD13 gene being knocked-out, prepared porcine fibroblasts, and a method for preparing a gene-edited pig with both CD163 gene and CD13 gene being knocked-out. The vector system of the present disclosure comprises a CD163 gene knockout vector and a CD13 gene knockout vector. The CD163 gene knockout vector comprises a gene editing vector backbone and a DNA fragment ligated to the gene editing vector backbone, with a nucleotide sequence of the DNA fragment being shown in any one of SEQ ID NOs: 1-3. The CD13 gene knockout vector comprises a gene editing vector backbone and a DNA fragment ligated to the gene editing vector backbone, a nucleotide sequence of the DNA fragment being shown in any one of SEQ ID NOs: 4-6.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: February 8, 2022
    Assignee: Shandong Landsee Genetics Co., Ltd.
    Inventors: Kui Li, Yulian Mu, Zhiguo Liu, Julang Li, Kui Xu, Yinghui Wei, Changli Ge, Xuehui Cai, Long Wang, Qimei Chen, Yang Qiu
  • Method for Preparing Porcine Fibroblasts with Both CD163 Gene and CD13 Gene Being Knocked-out
    Publication number: 20200323182
    Abstract: Provided is a double-gene knockout vector system, a method for preparing porcine fibroblasts with both CD163 gene and CD13 gene being knocked-out, prepared porcine fibroblasts, and a method for preparing a gene-edited pig with both CD163 gene and CD13 gene being knocked-out. The vector system of the present disclosure comprises a CD163 gene knockout vector and a CD13 gene knockout vector. The CD163 gene knockout vector comprises a gene editing vector backbone and a DNA fragment ligated to the gene editing vector backbone, with a nucleotide sequence of the DNA fragment being shown in any one of SEQ ID NOs: 1-3. The CD13 gene knockout vector comprises a gene editing vector backbone and a DNA fragment ligated to the gene editing vector backbone, a nucleotide sequence of the DNA fragment being shown in any one of SEQ ID NOs: 4-6.
    Type: Application
    Filed: April 9, 2019
    Publication date: October 15, 2020
    Inventors: Kui Li, Yulian Mu, Zhiguo Liu, Julang Li, Kui Xu, Yinghui Wei, Changli Ge, Xuehui Cai, Long Wang, Qimei Chen, Yang Qiu