Patents by Inventor Julia A. BRAUN

Julia A. BRAUN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Iron chelators in tumor therapy
    Patent number: 11931349
    Abstract: The present invention relates to a pharmaceutically compatible iron chelator or a prodrug thereof for use in treating and/or preventing cancer in a subject suspected or known to comprise hypoxic cancer cells, and use in treatment and/or prevention of a human papillomavirus (HPV) related lesion. The present invention further relates to a use of an iron chelator or prodrug thereof for inducing senescence in a cancer cell, preferably a hypoxic cancer cell; and to a method for inducing an irreversible proliferation arrest in cancer cells comprising a) contacting said cancer cells with an iron chelator or prodrug thereof and, thereby, b) inducing an irreversible proliferation arrest in said cancer cells.
    Type: Grant
    Filed: November 23, 2018
    Date of Patent: March 19, 2024
    Assignee: Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts
    Inventors: Felix Hoppe-Seyler, Julia A. Braun, Karin Hoppe-Seyler
  • IRON CHELATORS IN TUMOR THERAPY
    Publication number: 20210369692
    Abstract: The present invention relates to a pharmaceutically compatible iron chelator or a prodrug thereof for use in treating and/or preventing cancer in a subject suspected or known to comprise hypoxic cancer cells, and use in treatment and/or prevention of a human papillomavirus (HPV) related lesion. The present invention further relates to a use of an iron chelator or prodrug thereof for inducing senescence in a cancer cell, preferably a hypoxic cancer cell; and to a method for inducing an irreversible proliferation arrest in cancer cells comprising a) contacting said cancer cells with an iron chelator or prodrug thereof and, thereby, b) inducing an irreversible proliferation arrest in said cancer cells.
    Type: Application
    Filed: November 23, 2018
    Publication date: December 2, 2021
    Applicant: Deutsches Krebsforschungszentrum
    Inventors: Felix HOPPE-SEYLER, Julia A. BRAUN, Karin HOPPE-SEYLER