Patents by Inventor Julia A. SUNG

Julia A. SUNG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BISPECIFIC MOLECULES COMPRISING AN HIV-1 ENVELOPE TARGETING ARM
    Publication number: 20200354439
    Abstract: The invention is directed to bispecific molecules comprising an HIV-1 envelope targeting arm and an arm targeting an effector cell, compositions comprising these bispecific molecule and methods of use. In certain aspects, the bispecific molecules of the present invention can bind to two different targets or epitopes on two different cells within the first epitope is expressed on a different cell type than the second epitope, such that the bispecific molecules can bring the two cells together. In certain aspects, the bispecific molecules of the present invention can bind to two different cells, wherein the bispecific molecules comprises an arm with the binding specificity of A32, 7B2, CH27, CH28 or CH44.
    Type: Application
    Filed: June 2, 2020
    Publication date: November 12, 2020
    Applicants: Duke University, MacroGenics, Inc., The University of North Carolina at Chapel Hill
    Inventors: Barton F. HAYNES, Guido FERRARI, Scott KOENIG, Leslie S. JOHNSON, Chia-Ying Kao LAM, Julia A. SUNG, David M. MARGOLIS, Liqin LIU, Jeffrey Lee NORDSTROM
  • Bispecific molecules comprising an HIV-1 envelope targeting arm
    Patent number: 10717778
    Abstract: The invention is directed to bispecific molecules comprising an HIV-1 envelope targeting arm and an arm targeting an effector cell, compositions comprising these bispecific molecules and methods of use. In certain aspects, the bispecific molecules of the present invention can bind to two different targets or epitopes on two different cells wherein the first epitope is expressed on a different cell type than the second epitope, such that the bispecific molecules can bring the two cells together. In certain aspects, the bispecific molecules of the present invention can bind to two different cells, wherein the bispecific molecules comprises an arm with the binding specificity of A32, 7B2, CH27, CH28, or CH44.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: July 21, 2020
    Assignees: DUKE UNIVERSITY, MACROGENICS, INC., THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: Barton F. Haynes, Guido Ferrari, Scott Koenig, Leslie S. Johnson, Chia-Ying Kao Lam, Julia A. Sung, David M. Margolis, Liqin Liu, Jeffrey Lee Nordstrom
  • BISPECIFIC MOLECULES COMPRISING AN HIV-1 ENVELOPE TARGETING ARM
    Publication number: 20180148497
    Abstract: The invention is directed to bispecific molecules comprising an HIV-1 envelope targeting arm and an arm targeting an effector cell, compositions comprising these bispecific molecules and methods of use. In certain aspects, the bispecific molecules of the present invention can bind to two different targets or epitopes on two different cells wherein the first epitope is expressed on a different cell type than the second epitope, such that the bispecific molecules can bring the two cells together. In certain aspects, the bispecific molecules of the present invention can bind to two different cells, wherein the bispecific molecules comprises an arm with the binding specificity of A32, 7B2, CH27, CH28, or CH44.
    Type: Application
    Filed: September 29, 2015
    Publication date: May 31, 2018
    Applicants: Duke University, MacroGenics, Inc., The University of North Carolina at Chapel Hill
    Inventors: Barton F. HAYNES, Guido FERRARI, Scott KOENIG, Leslie S. JOHNSON, Chia-Ying Kao LAM, Julia A. SUNG, David M. MARGOLIS, Liqin LIU, Jeffrey Lee NORDSTROM