Abstract: Photo-responsive shape changing polymer compositions including photoinitiators that absorb light in the range about 400 nm to about 700 nm, a cross-linked polymer matrix and a polymerizable composition. Photopolymerization of the polymerizable composition sorbed in the cross-linked polymer matrix results in the shape change which manifests in the change in the refractive properties of the composition. The light dose required to effect the shape change; lock-in dose and the photobleaching dose are determined by the choice of the photoinitiator, electron donor and the hydrogen donor. These compositions are useful in the fabrication of coloured lenses, especially intraocular lenses.

Abstract: Photo-responsive shape changing polymer compositions including photoinitiators that absorb light in the range about 400 nm to about 700 nm, a cross-linked polymer matrix and a polymerizable composition. Photopolymerization of the polymerizable composition sorbed in the cross-linked polymer matrix results in the shape change which manifests in the change in the refractive properties of the composition. The light dose required to effect the shape change; lock-in dose and the photobleaching dose are determined by the choice of the photoinitiator, electron donor and the hydrogen donor. These compositions are useful in the fabrication of coloured lenses, especially intraocular lenses.

Abstract: Methods and systems for preparing nanoparticles. A source of a carrier fluid is connected to an inlet of a flow conduit, such as an intravenous solution administration tube with injection ports, such that the carrier fluid flows through the conduit. A substance (e.g., a drug solution or other substance solution) is introduced into the conduit at a first location causing substance nanoparticles to form within and continue to flow thought he conduit. A stabilizer is introduced into the conduit at a second location to cause a stabilizing effect on the nanoparticles. In some embodiments, the stabilizer may limit or deter agglomeration or growth of the nanoparticles, thereby limiting the size of the nanaparticles produced.