Abstract: The present application is directed to methods for modulating afucosylation of an antibody product that is produced in a bioreactor. The methods include the addition of mannose to the bioreactor to control the afucosylation of the antibody product, including increasing by afucosylation by 1% or more, relative to untreated bioreactor products.

Abstract: A data collaboration system includes first and second users providing first and second quantities of content data, respectively. The first and second users provide the first and second quantity of content data, respectively, to a collaboration environment. A user collaboration module within the collaboration environment has a plurality of data tools usable by the first and second users who, in collaboration, use the plurality of data tools to create a third quantity of content data from the first and second quantities of content data. A data processing platform is in communication with the collaboration environment, wherein the third quantity of content data is uploaded to the data processing platform and integrated with existing content data, wherein additional users access the data processing platform through additional collaboration environments and control at least part of the integration of the third quantity of content data within the data processing platform.