Patents by Inventor Julia Beck

Julia Beck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted S-alaninate derivatives
    Patent number: 11912692
    Abstract: The invention relates to substituted S-alaninate derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.
    Type: Grant
    Filed: August 11, 2023
    Date of Patent: February 27, 2024
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hartmut Beck, Stefanie Mesch, Alexandros Vakalopoulos, Nils Pfaff, Stefanie Zimmermann, Markus Follmann, Elisabeth Kersten, Guillaume Levilain, Kartrin Partikel, Andreas Peter Broehl, Stefan Heitmeier, Julia Dietze-Torres, Lutz Lehmann, Kersten Matthias Gericke, Frank Süßmeier, Lars Bärfacker, Alexander Hillisch, Adrian Tersteegen, Anja Buchmüller, Christoph Gerdes
  • Identifaction of cancer biomarkers by alignment of nucleic acid sequences
    Patent number: 11859251
    Abstract: CNA biomarkers can include nucleic acid sequences that are present in circulating nucleic acids obtained from circulatory systems of a population known to have cancer, but that are rarely present, if at all, in circulating nucleic acids obtained from circulatory systems of a control population. Information is received describing one or more sequences obtained from circulating nucleic acids in a population known to have cancer. Information is also received describing one or more sequences obtained from circulating nucleic acids in a control population. A cluster analysis within a predetermined portion of a genome uses the one or more sequences in the circulating nucleic acids obtained from the population known to have cancer and the one or more sequences in the circulating nucleic acids obtained from the control population. Information is generated identifying one or more biomarkers for the cancer based on a cluster search within results of the cluster analysis.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: January 2, 2024
    Assignee: CHRONIX BIOMEDICAL
    Inventors: Ekkehard Schutz, Julia Beck, Howard Urnovitz
  • METHODS FOR PRECISE AND BIAS-FREE QUANTIFICATION OF CELL-FREE DNA
    Publication number: 20230121271
    Abstract: This invention provides a method of quantifying the amount of diagnostic cell-free DNA (cfDNA) in a cfDNA sample from a subject. Specifically, the method comprising quantifying the amount of a diagnostic cfDNA in a cfDNA sample from a subject using two or more PCR reactions, wherein the diagnostic cfDNA deviates from germline DNA of the subject for differentiating cfDNA between the shortening or lengthening of the individual's germline-originating cfDNA and the shortening or lengthening of the target diagnostic cfDNA from cells of interest that are present in the subject, such as cells from a tumor, a fetus (placenta) or a transplanted organ.
    Type: Application
    Filed: March 25, 2021
    Publication date: April 20, 2023
    Inventors: Ekkehard Schütz, Julia Beck
  • PROSTATE CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20230087365
    Abstract: The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: August 15, 2022
    Publication date: March 23, 2023
    Inventors: Ekkehard Schütz, Julia Beck, Howard Urnovitz
  • BREAST CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20220333213
    Abstract: The invention provides methods and reagents for diagnosing breast cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: June 27, 2022
    Publication date: October 20, 2022
    Inventors: Ekkehard Schuetz, Julia Beck, Howard Urnovitz
  • Method of determining a numeric index of tumor-associated copy number changes of circulating nucleic acids associated with prostate cancer
    Patent number: 11414706
    Abstract: The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Grant
    Filed: May 21, 2018
    Date of Patent: August 16, 2022
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schütz, Julia Beck, Howard Urnovitz
  • Breast cancer associated circulating nucleic acid biomarkers
    Patent number: 11377695
    Abstract: The invention provides methods and reagents for diagnosing breast cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: July 5, 2022
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schuetz, Julia Beck, Howard Urnovitz
  • DETECTION AND QUANTIFICATION OF DONOR CELL-FREE DNA IN THE CIRCULATION OF ORGAN TRANSPLANT RECIPIENTS
    Publication number: 20220025459
    Abstract: This invention provides methods, compositions, and kits relating to detecting donor cell-free DNA in the circulation of a transplant recipient for the early identification of transplant rejection or for detection of damage to transplant cells.
    Type: Application
    Filed: October 15, 2021
    Publication date: January 27, 2022
    Inventors: Ekkehard Schütz, Julia Beck
  • Detection and quantification of donor cell-free DNA in the circulation of organ transplant recipients
    Patent number: 11155872
    Abstract: This invention provides methods, compositions, and kits relating to detecting donor cell-free DNA in the circulation of a transplant recipient for the early identification of transplant rejection or for detection of damage to transplant cells.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: October 26, 2021
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schutz, Julia Beck
  • Methods of quantifying cell-free DNA
    Patent number: 10570443
    Abstract: This invention provides a method of quantifying chimeric DNA in a cell-free DNA sample.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: February 25, 2020
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schutz, Julia Beck
  • Analyzing circulating nucleic acids to identify a biomarker representative of cancer presented by a patient population
    Patent number: 10378064
    Abstract: CNA biomarkers can include nucleic acid sequences that are present in circulating nucleic acids obtained from circulatory systems of a population known to have cancer, but that are rarely present, if at all, in circulating nucleic acids obtained from circulatory systems of a control population. Information is received describing one or more sequences obtained from circulating nucleic acids in a population known to have cancer. Information is also received describing one or more sequences obtained from circulating nucleic acids in a control population. A cluster analysis within a predetermined portion of a genome uses the one or more sequences in the circulating nucleic acids obtained from the population known to have cancer and the one or more sequences in the circulating nucleic acids obtained from the control population. Information is generated identifying one or more biomarkers for the cancer based on a cluster search within results of the cluster analysis.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: August 13, 2019
    Assignee: CHRONIX BIOMEDICAL
    Inventors: Ekkehard Schutz, Julia Beck, Howard Urnovitz
  • PROSTATE CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20190185928
    Abstract: The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 20, 2019
    Inventors: Ekkehard SCHÜTZ, Julia BECK, Howard URNOVITZ
  • COLORECTAL CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20190136314
    Abstract: The invention provides methods and reagents for diagnosing colorectal cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: June 13, 2018
    Publication date: May 9, 2019
    Inventors: Ekkehard Schutz, Julia Beck, Howard Urnovitz
  • BREAST CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20190078165
    Abstract: The invention provides methods and reagents for diagnosing breast cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: August 13, 2018
    Publication date: March 14, 2019
    Inventors: Ekkehard Schuetz, Julia Beck, Howard Urnovitz
  • Prostate cancer associated circulating nucleic acid biomarkers
    Patent number: 10214775
    Abstract: The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: February 26, 2019
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schutz, Julia Beck, Howard Urnovitz
  • DETECTION AND QUANTIFICATION OF DONOR CELL-FREE DNA IN THE CIRCULATION OF ORGAN TRANSPLANT RECIPIENTS
    Publication number: 20180346982
    Abstract: This invention provides methods, compositions, and kits relating to detecting donor cell-free DNA in the circulation of a transplant recipient for the early identification of transplant rejection or for detection of damage to transplant cells.
    Type: Application
    Filed: March 13, 2018
    Publication date: December 6, 2018
    Inventors: Ekkehard SCHUTZ, Julia BECK
  • Prostate Cancer Associated Circulating Nucleic Acid Biomarkers
    Publication number: 20180340233
    Abstract: The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: May 21, 2018
    Publication date: November 29, 2018
    Inventors: Ekkehard Schütz, Julia Beck, Howard Urnovitz
  • Breast cancer associated circulating nucleic acid biomarkers
    Patent number: 10047397
    Abstract: The invention provides methods and reagents for diagnosing breast cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: August 14, 2018
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schuetz, Julia Beck, Howard Urnovitz
  • Personalized biomarkers for cancer
    Patent number: 9909186
    Abstract: The invention provides methods and reagents for identifying personalized tumor biomarkers for a patient that has a solid tumor and methods of using such biomarkers to monitor patient responses to therapeutic treatments.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: March 6, 2018
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schütz, Julia Beck, Howard Urnovitz
  • METHODS OF QUANTIFYING CELL-FREE DNA
    Publication number: 20170327869
    Abstract: This invention provides a method of quantifying chimeric DNA in a cell-free DNA sample.
    Type: Application
    Filed: September 30, 2015
    Publication date: November 16, 2017
    Inventors: Ekkehard Schutz, Julia Beck