Patents by Inventor Julia Hui

Julia Hui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for screening cereblon modifying compounds
    Patent number: 12590953
    Abstract: A method of screening a cereblon modifying compound for treating a disease or disorder, comprising: obtaining a sample; determining a first protein level of SALL4; administering the cereblon modifying compound to the sample; determining a second protein level of SALL4; comparing the first level and the second protein level of SALL4 to determine if the cereblon modifying compound induces degradation of SALL4; and selecting the cereblon modifying compound that does not induce degradation of SALL4.
    Type: Grant
    Filed: June 28, 2022
    Date of Patent: March 31, 2026
    Assignee: Celgene Corporation
    Inventors: Mary Matyskiela, Philip Chamberlain, Suzana Sturlini Couto, Katherine Stamp, Philip J. Sherratt, Gang Lu, Julia Hui
  • METHODS FOR SCREENING CEREBLON MODIFYING COMPOUNDS
    Publication number: 20220412953
    Abstract: A method of screening a cereblon modifying compound for treating a disease or disorder, comprising: obtaining a sample; determining a first protein level of SALL4; administering the cereblon modifying compound to the sample; determining a second protein level of SALL4; comparing the first level and the second protein level of SALL4 to determine if the cereblon modifying compound induces degradation of SALL4; and selecting the cereblon modifying compound that does not induce degradation of SALL4.
    Type: Application
    Filed: June 28, 2022
    Publication date: December 29, 2022
    Applicant: CELGENE CORPORATION
    Inventors: Mary MATYSKIELA, Philip CHAMBERLAIN, Suzana Sturlini COUTO, Katherine STAMP, Philip J. SHERRATT, Gang LU, Julia HUI
  • Methods for screening cereblon modifying compounds
    Patent number: 11402372
    Abstract: A method of screening a cereblon modifying compound for treating a disease or disorder, comprising: obtaining a sample; determining a first protein level of SALL4; administering the cereblon modifying compound to the sample; determining a second protein level of SALL4; comparing the first level and the second protein level of SALL4 to determine if the cereblon modifying compound induces degradation of SALL4; and selecting the cereblon modifying compound that does not induce degradation of SALL4.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: August 2, 2022
    Assignee: CELGENE CORPORATION
    Inventors: Mary Matyskiela, Philip Chamberlain, Suzana Sturlini Couto, Katherine Stamp, Philip J. Sherratt, Gang Lu, Julia Hui
  • METHODS FOR SCREENING CEREBLON MODIFYING COMPOUNDS
    Publication number: 20190219562
    Abstract: A method of screening a cereblon modifying compound for treating a disease or disorder, comprising: obtaining a sample; determining a first protein level of SALL4; administering the cereblon modifying compound to the sample; determining a second protein level of SALL4; comparing the first level and the second protein level of SALL4 to determine if the cereblon modifying compound induces degradation of SALL4; and selecting the cereblon modifying compound that does not induce degradation of SALL4.
    Type: Application
    Filed: January 10, 2019
    Publication date: July 18, 2019
    Applicant: CELGENE CORPORATION
    Inventors: Mary Matyskiela, Philip Chamberlain, Suzana Sturlini Couto, Katherine Stamp, Philip J. Sherratt, Gang Lu, Julia Hui