Patents by Inventor Julia Kirshner

Julia Kirshner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for isolating invasive and metastatic cells for evaluating therapeutics and prediction of metastatic capacity
    Patent number: 11124756
    Abstract: Embodiments provide methods to produce an assembly that mimics in vitro the human microenvironment of a primary tumor site, a secondary distant organ, and circulation. Methods and apparatuses that provide a platform for the isolation of primary tumor, invasive, and metastatic cells to be used for evaluation of therapeutic efficacy and diagnostics as applied to metastatic cancers are also provided.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: September 21, 2021
    Assignee: zPredicta, Inc.
    Inventors: Julia Kirshner, Mukti Rajen Parikh
  • Method and apparatus for isolating invasive and metastatic cells for evaluating therapeutics and prediction of metastatic capacity
    Patent number: 10501717
    Abstract: Embodiments provide methods to produce an assembly that mimics in vitro the human microenvironment of a primary tumor site, a secondary distant organ, and circulation. Methods and apparatuses that provide a platform for the isolation of primary tumor, invasive, and metastatic cells to be used for evaluation of therapeutic efficacy and diagnostics as applied to metastatic cancers are also provided.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: December 10, 2019
    Assignee: zPredicta, Inc.
    Inventors: Julia Kirshner, Mukti Rajen Parikh
  • METHOD AND APPARATUS FOR ISOLATING INVASIVE AND METASTATIC CELLS FOR EVALUATING THERAPEUTICS AND PREDICTION OF METASTATIC CAPACITY
    Publication number: 20190284520
    Abstract: Embodiments provide methods to produce an assembly that mimics in vitro the human microenvironment of a primary tumor site, a secondary distant organ, and circulation. Methods and apparatuses that provide a platform for the isolation of primary tumor, invasive, and metastatic cells to be used for evaluation of therapeutic efficacy and diagnostics as applied to metastatic cancers are also provided.
    Type: Application
    Filed: December 11, 2018
    Publication date: September 19, 2019
    Inventors: Julia Kirshner, Mukti Rajen Parikh
  • SCREENING OF IMMUNO-MODULATORY THERAPIES
    Publication number: 20190169562
    Abstract: Embodiments provide methods of preparing a platform, which entails, among others, contacting a) a culture comprising a medium or growth matrix comprising an immune cell, with b) a biological matrix mimetic comprising a target cell such a cancer cell, and allowing, under suitable conditions, the immune cell to migrate to the biological matrix mimetic.
    Type: Application
    Filed: July 31, 2017
    Publication date: June 6, 2019
    Applicant: zPredicta, Inc.
    Inventors: Julia Kirshner, Mukti Rajen Parikh
  • METHOD AND APPARATUS FOR ISOLATING INVASIVE AND METASTATIC CELLS FOR EVALUATING THERAPEUTICS AND PREDICTION OF METASTATIC CAPACITY
    Publication number: 20160340635
    Abstract: Embodiments provide methods to produce an assembly that mimics in vitro the human microenvironment of a primary tumor site, a secondary distant organ, and circulation. Methods and apparatuses that provide a platform for the isolation of primary tumor, invasive, and metastatic cells to be used for evaluation of therapeutic efficacy and diagnostics as applied to metastatic cancers are also provided.
    Type: Application
    Filed: January 21, 2015
    Publication date: November 24, 2016
    Inventors: Julia Kirshner, Mukti Rajen Parikh
  • METHOD AND APPARATUS FOR EVALUATING THERAPEUTICS ON CANCER STEM CELLS
    Publication number: 20090117653
    Abstract: Embodiments provide cell culture methods to produce a 3-D model assembly that mimics in vitro the microenvironment of human bone marrow, where cells occupy distinct niches. Methods and apparatuses are provided for the efficient testing of cancer, including malignant hematopoietic cancers and metastatic spread to the bone marrow of solid tumors, and of other diseases of the blood and bone marrow. Methods and apparatuses are further provided in embodiments for the investigation of bone marrow cell biological characteristics and for the testing of therapeutics for nonmalignant diseases of the blood and bone marrow.
    Type: Application
    Filed: October 29, 2008
    Publication date: May 7, 2009
    Applicant: Governors of the University of Alberta
    Inventors: Julia Kirshner, Linda Pilarski