Patents by Inventor Julia Leslie

Julia Leslie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Micro-organ device
    Patent number: 8580546
    Abstract: A method for fabricating a micro-organ device comprises providing a microscale support having one or more microfluidic channels and one or more micro-chambers for housing a micro-organ and printing a micro-organ on the microscale support using a cell suspension in a syringe controlled by a computer-aided tissue engineering system, wherein the cell suspension comprises cells suspended in a solution containing a material that functions as a three-dimensional scaffold. The printing is performed with the computer-aided tissue engineering system according to a particular pattern. The micro-organ device comprises at least one micro-chamber each housing a micro-organ; and at least one microfluidic channel connected to the micro-chamber, wherein the micro-organ comprises cells arranged in a configuration that includes microscale spacing between portions of the cells to facilitate diffusion exchange between the cells and a medium supplied from the at least one microfluidic channel.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: November 12, 2013
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: Steve R. Gonda, Robert C. Chang, Binil Starly, Christopher Culbertson, Heidi L. Holtorf, Wei Sun, Julia Leslie
  • Micro-organ device
    Patent number: 8343740
    Abstract: A method for fabricating a micro-organ device comprises providing a microscale support having one or more microfluidic channels and one or more micro-chambers for housing a micro-organ and printing a micro-organ on the microscale support using a cell suspension in a syringe controlled by a computer-aided tissue engineering system, wherein the cell suspension comprises cells suspended in a solution containing a material that functions as a three-dimensional scaffold. The printing is performed with the computer-aided tissue engineering system according to a particular pattern. The micro-organ device comprises at least one micro-chamber each housing a micro-organ; and at least one microfluidic channel connected to the micro-chamber, wherein the micro-organ comprises cells arranged in a configuration that includes microscale spacing between portions of the cells to facilitate diffusion exchange between the cells and a medium supplied from the at least one microfluidic channel.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: January 1, 2013
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: Steve R. Gonda, Iris von Gustedt-Gonda, legal representative, Robert C. Chang, Binil Starly, Christopher Culbertson, Heidi L. Holtorf, Wei Sun, Julia Leslie
  • Micro-Organ Device
    Publication number: 20080261288
    Abstract: A method for fabricating a micro-organ device comprises providing a microscale support having one or more microfluidic channels and one or more micro-chambers for housing a micro-organ and printing a micro-organ on the microscale support using a cell suspension in a syringe controlled by a computer-aided tissue engineering system, wherein the cell suspension comprises cells suspended in a solution containing a material that functions as a three-dimensional scaffold. The printing is performed with the computer-aided tissue engineering system according to a particular pattern. The micro-organ device comprises at least one micro-chamber each housing a micro-organ; and at least one microfluidic channel connected to the micro-chamber, wherein the micro-organ comprises cells arranged in a configuration that includes microscale spacing between portions of the cells to facilitate diffusion exchange between the cells and a medium supplied from the at least one microfluidic channel.
    Type: Application
    Filed: March 28, 2008
    Publication date: October 23, 2008
    Inventors: Steve R. Gonda, Iris von Gustedt-Gonda, Robert C. Chang, Binil Starly, Christopher Culbertson, Heidi L. Holtorf, Wie Sun, Julia Leslie