Patents by Inventor Julia T. Warren

Julia T. Warren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant tumor necrosis factor receptor superfamily (TNFsfR) ligands and methods of making and using same
    Patent number: 11248036
    Abstract: Methods for constructing efficient inhibitors of target TNF superfamily receptors, single chain target TNF superfamily ligands that inhibit of target TNF superfamily receptors while failing to engage or inhibit non-target TNF superfamily receptors, and methods of their use to treat diseases are provided. Single chain RANKL, TNF, and TRAIL ligands that effectively inhibit their target receptors while failing to inhibit non-target TNF superfamily receptors are also provided.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: February 15, 2022
    Assignee: Washington University
    Inventors: Christopher Nelson, Steven Teitelbaum, Daved Fremont, Julia T. Warren
  • MUTANT TUMOR NECROSIS FACTOR RECEPTOR (TNFR) LIGANDS AND METHODS OF MAKING AND USING SAME
    Publication number: 20200199196
    Abstract: Methods for constructing efficient inhibitors of target TNF superfamily receptors, single chain target TNF superfamily ligands that inhibit of target TNF superfamily receptors while failing to engage or inhibit non-target TNF superfamily receptors, and methods of their use to treat diseases are provided. Single chain RANKL, TNF, and TRAIL ligands that effectively inhibit their target receptors while failing to inhibit non-target TNF superfamily receptors are also provided.
    Type: Application
    Filed: December 17, 2019
    Publication date: June 25, 2020
    Inventors: Christopher Nelson, Steven Teitelbaum, Daved Fremont, Julia T. Warren
  • Oligomers for TNF superfamily inhibition, methods of making and using
    Patent number: 10550169
    Abstract: Methods for constructing efficient inhibitors of target TNF superfamily receptors, single chain target TNF superfamily ligands that inhibit of target TNF superfamily receptors while failing to engage or inhibit non-target TNF superfamily receptors, and methods of their use to treat diseases are provided. Single chain RANKL, TNF, and TRAIL ligands that effectively inhibit their target receptors while failing to inhibit non-target TNF superfamily receptors are also provided.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: February 4, 2020
    Assignee: Washington University
    Inventors: Steven Teitelbaum, Daved Fremont, Julia T. Warren, Christopher Nelson
  • Oligomers for TNF Superfamily Inhibition, Methods of Making and Using
    Publication number: 20180312569
    Abstract: Methods for constructing efficient inhibitors of target TNF superfamily receptors, single chain target TNF superfamily ligands that inhibit of target TNF superfamily receptors while failing to engage or inhibit non-target TNF superfamily receptors, and methods of their use to treat diseases are provided. Single chain RANKL, TNF, and TRAIL ligands that effectively inhibit their target receptors while failing to inhibit non-target TNF superfamily receptors are also provided.
    Type: Application
    Filed: February 12, 2018
    Publication date: November 1, 2018
    Inventors: Steven Teitelbaum, Daved Fremont, Julia T. Warren, Christopher Nelson
  • Oligomers for TNF superfamily inhibition
    Patent number: 9914761
    Abstract: Methods for constructing efficient inhibitors of target TNF superfamily receptors, single chain target TNF superfamily ligands that inhibit of target TNF superfamily receptors while failing to engage or inhibit non-target TNF superfamily receptors, and methods of their use to treat diseases are provided. Single chain RANKL, TNF, and TRAIL ligands that effectively inhibit their target receptors while failing to inhibit non-target TNF superfamily receptors are also provided.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: March 13, 2018
    Assignee: Washington University
    Inventors: Steven Teitelbaum, Daved Fremont, Julia T. Warren, Christopher Nelson
  • OLIGOMERS FOR TNF SUPERFAMILY INHIBITION, METHODS OF MAKING AND USING
    Publication number: 20160009783
    Abstract: Methods for constructing efficient inhibitors of target TNF superfamily receptors, single chain target TNF superfamily ligands that inhibit of target TNF superfamily receptors while failing to engage or inhibit non-target TNF superfamily receptors, and methods of their use to treat diseases are provided. Single chain RANKL, TNF, and TRAIL ligands that effectively inhibit their target receptors while failing to inhibit non-target TNF superfamily receptors are also provided.
    Type: Application
    Filed: July 10, 2015
    Publication date: January 14, 2016
    Inventors: Steven Teitelbaum, Daved Fremont, Julia T. Warren, Christopher Nelson