Patents by Inventor Julia Zeitlinger

Julia Zeitlinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and kits for identifying polypeptide binding sites in a genome
    Patent number: 10287628
    Abstract: The present invention provides, inter alia, methods and kits for identifying where a polypeptide of interest binds in a genome. The methods include a) carrying out a chromatin immunoprecipitation coupled to exonuclease digestion (ChIP-exo) process with an antibody against the polypeptide of interest; (b) extracting a polynucleotide fragment to which the polypeptide of interest binds; (c) carrying out a library preparation protocol adapted from an individual nucleotide resolution UV cross-linking and immunoprecipitation (iCLIP) process on the ChIP-exo processed polynucleotide fragment; and (d) sequencing the resulting polynucleotides. The kits include: (a) reagents sufficient to carry out ChIP-exo; (b) reagents sufficient to carry out the library preparation protocol adapted from the iCLIP process; and (c) instructions for use.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: May 14, 2019
    Assignee: Stowers Institute for Medical Research
    Inventors: Julia Zeitlinger, Qiye He, Jeffrey Johnston
  • METHODS AND KITS FOR IDENTIFYING POLYPEPTIDE BINDING SITES IN A GENOME
    Publication number: 20170362650
    Abstract: The present invention provides, inter alia, methods and kits for identifying where a polypeptide of interest binds in a genome. The methods include a) carrying out a chromatin immunoprecipitation coupled to exonuclease digestion (ChIP-exo) process with an antibody against the polypeptide of interest; (b) extracting a polynucleotide fragment to which the polypeptide of interest binds; (c) carrying out a library preparation protocol adapted from an individual nucleotide resolution UV cross-linking and immunoprecipitation (iCLIP) process on the ChIP-exo processed polynucleotide fragment; and (d) sequencing the resulting polynucleotides. The kits include: (a) reagents sufficient to carry out ChIP-exo; (b) reagents sufficient to carry out the library preparation protocol adapted from the iCLIP process; and (c) instructions for use.
    Type: Application
    Filed: December 18, 2015
    Publication date: December 21, 2017
    Inventors: Julia Zeitlinger, Qiye He, Jeff Johnston