Patents by Inventor Julian A. Davies

Julian A. Davies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Iron(III) complexes as contrast agents for image enhancement in magnetic resonance imaging
    Patent number: 6294152
    Abstract: A compound of formula (I): wherein, R1 is independently selected from methyl and ethyl and R2 is independently selected from hydrogen, alkyl, and substituted alkyl. The compound is capable of functioning as a ligand and complexing with paramagnetic Fe(III) ion for use as a second-sphere contrast enhancing agent for magnetic resonance imaging of tissue. The present invention also relates to a method of administering the second sphere contrast agent.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: September 25, 2001
    Assignees: The University of Toledo, Schering Aktiengesellschaft of Germany
    Inventors: Julian A. Davies, Wolfgang Ebert, Bernd Raduechel, Heribert Schmitt-Willich
  • Contrast agents for image enhancement in magnetic resonance imaging
    Patent number: 6146615
    Abstract: A compound of formula (I): ##STR1## wherein, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are selected independently from hydrogen, alkyl, and alkyl substituted with one or more --O-- atoms, or where R.sup.1, R.sup.2 and R.sup.3, R.sup.4 are ring residues. The compound is capable of functioning as a ligand and complexing with paramagnetic Fe(III) ion for use as a second-sphere contrast enhancing agent for magnetic resonance imaging of tissue, and a method of administering the second sphere contrast agent.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: November 14, 2000
    Assignees: The University of Toledo, Schering Aktiengesellschaft
    Inventors: Julian A. Davies, Wolfgang Ebert, Bernd Raduechel
  • Second sphere complexes as relaxation agents for image enhancement in magnetic resonance imaging
    Patent number: 5494656
    Abstract: A second sphere contrast enhancing agent for magnetic resonance imaging comprises a paramagnetic metal ion having catecholate ligands coordinated thereto and having water molecules hydrogen bonded to the catecholate ligands.
    Type: Grant
    Filed: March 17, 1995
    Date of Patent: February 27, 1996
    Assignee: The University of Toledo
    Inventor: Julian A. Davies
  • Process for the manufacture of electroceramics such as titanates and zirconates
    Patent number: 5082812
    Abstract: Mixed metal oxide electroceramics are produced from dissolved metal oxides using aqueous processing. For example, zirconates and titanates are manufactured from titania and zirconia using aqueous processing by forming an ammonium titanium complex, or an ammonium zironium complex, which can then be further reacted to release ammonia and form a metal titane or metal zirconate precursor. The precursor is then pyrolyzed to the corresponding oxide, e.g. barium and/or strontium titanate.
    Type: Grant
    Filed: December 12, 1989
    Date of Patent: January 21, 1992
    Assignee: The University of Toledo
    Inventors: Julian A. Davies, Sylvain Dutremez