Patents by Inventor Julian A. Gray

Julian A. Gray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dihydropyridine Compounds for Neurodegenerative Diseases and Dementia
    Publication number: 20090131480
    Abstract: The invention provides methods for treating and/or preventing cognitive impairments, dementia, or neurodegenerative diseases and disorders (e.g., Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis) in patients by administering therapeutically effective amounts of an AMPA receptor antagonist (e.g., 1,2-dihydropyridine compounds) and therapeutically effective amounts of nootropics (e.g., cholinesterase inhibitors) to patients. The invention also provides combinations, commercial packages, and pharmaceutical compositions comprising therapeutically effective amounts of AMPA receptor antagonists (e.g., 1,2-dihydropyridine compounds) and therapeutically effective amounts nootropics (e.g., cholinesterase inhibitors). The 1,2-dihydropyridine compound may be, for example, 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one. The cholinesterase inhibitor may be, for example, donepezil.
    Type: Application
    Filed: April 4, 2006
    Publication date: May 21, 2009
    Applicant: EISAI Co., Ltd.
    Inventors: Julian A. Gray, Yoshiharu Yamanishi, Julian A. Gray, Yoshiharu Yamanishi, Nobuyuki Mori, Scott Fields
  • Uses of 4-(3-phosphono-2-propenyl)-2-pierazinecarboxylic acid
    Patent number: 4939129
    Abstract: The uses of piperazinecarboxylic acid in the treatment of disorders characterized by reduced drive and/or social withdrawal, sleep disturbances or migraine.
    Type: Grant
    Filed: March 9, 1989
    Date of Patent: July 3, 1990
    Assignee: Sandoz Ltd.
    Inventors: Arnold K. Dixon, Julian A. Gray
  • Method of treating migraine
    Patent number: 4916125
    Abstract: A method of treating migraine in a subject in need of such treatment comprising administering to said subject a therapeutically effective amount of a phosphonic acid.
    Type: Grant
    Filed: July 11, 1989
    Date of Patent: April 10, 1990
    Assignee: Sandoz Ltd.
    Inventors: Paul L. Herrling, Julian A. Gray