Patents by Inventor Julian Sampson

Julian Sampson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening methods and sequences relating thereto
    Publication number: 20060183134
    Abstract: A screening method for identifying an individual having a pre-disposition towards having a cancer is disclosed, which screening method comprises the steps of: (a) obtaining a test sample comprising a nucleotide sequence comprised in the MYH gene of the individual or an amino acid sequence of a polypeptide expressed thereby; and (b) comparing a region of the test sample sequence with the corresponding region of the wild type sequence, whereby a difference between the test sample sequence and the wild type sequence signifies that the individual is pre-disposed to having the cancer; and wherein the difference comprises a specified variation.
    Type: Application
    Filed: October 11, 2005
    Publication date: August 17, 2006
    Applicant: Myriad Genetics, Incorporated
    Inventors: Julian Sampson, Jeremy Cheadle
  • Screening methods and sequences relating thereto
    Publication number: 20050003359
    Abstract: A screening method for identifying an individual having a pre-disposition towards having a cancer is disclosed, which screening method comprises the steps of: (a) obtaining a test sample comprising a nucleotide sequence comprised in a gene in a gene in a base excision repair (BER) pathway of the individual or an amino acid sequence of a polypeptide expressed thereby; and (b) comparing a region of the test sample sequence with the corresponding region of the wild type sequence, whereby a difference between the test sample sequence and the wild type sequence signifies that the individual is pre-disposed to having the cancer; and wherein the difference comprises a specified variation. The specified variation can be the known mutation in the human MYH protein, G382D-hMYH or a nucleotide sequence encoding it, or it can be one or more novel variations, namely, Y165C, E466X, and Y90X, or the respective corresponding nucleotide sequences.
    Type: Application
    Filed: August 2, 2002
    Publication date: January 6, 2005
    Inventors: Julian Sampson, Jeremy Cheadle
  • Polycystic kidney disease 12 gene and uses thereof
    Patent number: 6656681
    Abstract: The present invention relates to the polycystic kidney disease 1 (PKD1) gene and its nucleic acid sequence, mutations thereof in patients having PKD1-associated disorders, the protein encoded by the PKD1 gene or its mutants, and their uses in disease diagnosis and therapy.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: December 2, 2003
    Inventors: Peter Charles Harris, Belen Peral, Christopher J. Ward, James Hughes, Martin Hendrik Breuning, Dorothea Johanna Maria Peters, Jeroen Hendrik Roelfsema, Julian Sampson, Dirkje Jorijntje Johanna Halley, Mark David Nellist, Lambertus Antonius Jacobus Janssen, Ajenne Lique Wilhelma Hesseling
  • Polycystic kidney disease 1 gene and uses thereof
    Patent number: 6485960
    Abstract: The present invention relates to the polycystic kidney disease 1 (PKD1) gene and its nucleic acid sequence, mutations thereof in patients having PKD1-associated disorders, the protein encoded by the PKD1 gene or its mutants, and their uses in disease diagnosis and therapy.
    Type: Grant
    Filed: April 14, 1995
    Date of Patent: November 26, 2002
    Assignee: Medical Research Council
    Inventors: Peter Charles Harris, Belen Peral, Christopher J. Ward, James Hughes, Martin Hendrik Breuning, Dorothea Johanna Maria Peters, Jeroen Hendrik Roelfsema, Julian Sampson, Dirkje Jorijntje Johanna Halley, Mark David Nellist, Lambertus Antonius Jacobus Janssen, Ajenne Lique Wilhelma Hesseling
  • Polycystic kidney disease 1 gene and uses thereof
    Patent number: 6380360
    Abstract: The present invention relates to the polycystic kidney disease 1 (PKD1) gene and its nucleic acid sequence, mutations thereof in patients having PKD1-associated disorders, the protein encoded by the PKD1 gene or its mutants, and their uses in disease diagnosis and therapy.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: April 30, 2002
    Assignee: Medical Research Council
    Inventors: Peter Charles Harris, Belen Peral, Christopher J. Ward, James Hughes, Martin Hendrik Breuning, Dorothea Johanna Maria Peters, Jeroen Hendrik Roelfsema, Julian Sampson, Dirkje Jorijntje Johanna Halley, Mark David Nellist, Lambertus Antonius Jacobus Janssen, Ajenne Lique Wilhelma Hesseling