Abstract: Biocidal compositions containing organoselenium compounds are disclosed, as well as methods of producing and using same.

Abstract: Biocidal compositions containing organoselenium compounds are disclosed, as well as methods of producing and using same.

Abstract: Anti-microbial orthodontic apparatus and anti-microbial orthodontic compositions comprise an effective amount of a selenium compound. Kits containing apparatus and/or compositions are disclosed, along with methods of producing and using said anti-microbial orthodontic apparatus and anti-microbial orthodontic compositions.

Abstract: The presently disclosed and claimed invention is directed to anti-microbial orthodontic apparatus and anti-microbial orthodontic compositions comprising an effective amount of a selenium compound, kits containing same, and methods of producing and using said anti-microbial orthodontic apparatus and anti-microbial orthodontic compositions.

Abstract: Biocidal formulations that include a selenium compound selected from the group consisting of RSeH, RSeR?, RSeSeR, RseSeR?, and RseX, wherein each of R and R? include an aliphatic or phenolic residue, and wherein X is a protecting group selected from the group consisting of a halogen, an imide, a cyanide, an azide, a phosphate, a sulfate, a nitrate, a carbonate, selenium dioxide, and combinations thereof, are provided. The selenium compounds may be incorporated into an acrylate polymer matrix, or may be incorporated into a molten plastic material. Methods for preventing growth of a species of interest on an object or in a composition are also provided.

Abstract: Biocidal formulations that include a selenium compound selected from the group consisting of RSeH, RSeR?, RSeSeR, RseSeR?, and RseX, wherein each of R and R? include an aliphatic or phenolic residue, and wherein X is a protecting group selected from the group consisting of a halogen, an imide, a cyanide, an azide, a phosphate, a sulfate, a nitrate, a carbonate, selenium dioxide, and combinations thereof, are provided. The selenium compounds may be incorporated into an acrylate polymer matrix, or may be incorporated into a molten plastic material. Methods for preventing growth of a species of interest on an object or in a composition are also provided.

Abstract: The presently disclosed and claimed invention is directed to anti-microbial orthodontic apparatus and anti-microbial orthodontic compositions comprising an effective amount of a selenium compound, kits containing same, and methods of producing and using said anti-microbial orthodontic apparatus and anti-microbial orthodontic compositions.

Abstract: Biocidal formulations that include a selenium compound selected from the group consisting of RSeH, RSeR, RSeR?, RSeSeR, RseSeR?, and RseX, wherein each of R and R? is an aliphatic or phenolic residue, and wherein X is a protecting group selected from the group consisting of a halogen, an imide, a cyamide, an azide, a phosphate, a sulfate, a nitrate, a carbonate, selenium dioxide, and combinations thereof, are provided. The selenium compounds may be disposed in a mixture or solution or deposited on a surface and non-covalently attached thereto, or the selenium compounds may be present in a suspension and maintained therein through non-covalent interactions. Methods for preventing growth of a species of interest on an object or in a composition are also provided.

Abstract: A synthesis of and use for L-Se-methylselenocysteine as a nutriceutical is described, based upon the knowledge that L-Se-methylselenocysteine is less toxic than L-selenomethionine towards normal cells. The synthesis proceeds by mixing N-(tert-butoxycarbonyl)-L-serine with a dialkyl diazodicarboxylate and at least one of a trialkylphosphine, triarylphosphine, and phosphite to form a first mixture that includes N-(tert-butoxycarbonyl)-L-serine ?-lactone. Methyl selenol or its salt is mixed with the N-(tert-butoxycarbonyl)-L-serine ?-lactone to form a second mixture that includes N-(tert-butoxycarbonyl)-Se-methylselenocysteine. The tert-butoxycarbonyl group is removed from the N-(tert-butoxycarbonyl)-Se-methylselenocysteine to form L-Se-methylselenocysteine. This synthesis significantly improves the manufacturability, manufacturing efficiency, and utility of this naturally occurring rare form of organic-selenium.