Patents by Inventor Juliane Mills

Juliane Mills has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dimeric high affinity EGFR constructs and uses thereof
    Patent number: 8278415
    Abstract: Polypeptides comprising EGFR extracellular domains I-III capable of forming dimeric EGF-binding proteins are provided. The dimeric construct of the invention is useful in applications where high affinity EGF binding is desired and can be used to select agents capable of binding to native EGFR in the presence of EGF.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: October 2, 2012
    Assignee: Centocor, Inc.
    Inventors: Wang Bryan, Frank Shi, Juliane Mills
  • DIMERIC HIGH AFFINITY EGFR CONSTRUCTS AND USES THEREOF
    Publication number: 20100098681
    Abstract: Polypeptides comprising EGFR extracellular domains I-III capable of forming dimeric EGF-binding proteins are provided. The dimeric construct of the invention is useful in applications where high affinity EGF binding is desired and can be used to select agents capable of binding to native EGFR in the presence of EGF.
    Type: Application
    Filed: December 20, 2007
    Publication date: April 22, 2010
    Inventors: Bryan Wang, Frank Shi, Juliane Mills
  • BMP-7 variant compositions, methods and uses
    Patent number: 7659250
    Abstract: Human Bone Morphogenic Protein 7 (hBMP-7) variant peptide chains, nucleic acids encoding these peptide chains, and methods of making and using the foregoing are disclosed.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: February 9, 2010
    Assignee: Centocor, Inc.
    Inventors: Bernard Amegadzie, Mark Cunningham, Haimanti Dorai, Jeffrey Luo, Juliane Mills, Bethany Swencki-Underwood
  • NOVEL RECOMBINANT PROTEINS WITH N-TERMINAL FREE THIOL
    Publication number: 20090239790
    Abstract: The present invention relates to novel modified proteins having N-terminal free thiols that can be produced by recombinant methods and are ready for further chemical derivatization. In particular, the invention relates to erythropoietin conjugate compounds having altered biochemical, physiochemical and pharmacokinetic properties.
    Type: Application
    Filed: June 2, 2009
    Publication date: September 24, 2009
    Inventors: Chadler Pool, Juliane Mills, Mark Cunningham
  • BMP-7 Variant Compositions, Methods and Uses
    Publication number: 20080032919
    Abstract: Human Bone Morphogenic Protein 7 (hBMP-7) variant peptide chains, nucleic acids encoding these peptide chains, and methods of making and using the foregoing are disclosed.
    Type: Application
    Filed: June 8, 2007
    Publication date: February 7, 2008
    Inventors: Bernard Amegadzie, Mark Cunningham, Haimanti Dorai, Jeffrey Luo, Juliane Mills, Bethany Swencki-Underwood
  • Novel recombinant proteins with N-terminal free thiol
    Publication number: 20050170457
    Abstract: The present invention relates to novel modified proteins having N-terminal free thiols that can be produced by recombinant methods and are ready for further chemical derivatization. In particular, the invention relates to erythropoietin conjugate compounds having altered biochemical, physiochemical and pharmacokinetic properties.
    Type: Application
    Filed: December 23, 2004
    Publication date: August 4, 2005
    Inventors: Chadler Pool, Juliane Mills, Mark Cunningham