Patents by Inventor Julianne Glowacki

Julianne Glowacki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for bone healing
    Patent number: 10251860
    Abstract: Disclosed herein are embodiments of a method of accelerating bone healing in a subject in need thereof, comprising administering to the subject a compound disclosed here. The method may further comprise selecting or identifying a subject that has bone damage, or is a risk of developing bone damage. The compound may be administered after bone damage has occurred, or it may be administered prophylactically. The compound may be administered to a subject that has not and/or will not be exposed to radiation. In other embodiments, the subject has been and/or will be exposed to radiation.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: April 9, 2019
    Assignees: University of Pittsburgh—of the Commonwealth System of Higher Education, The Brigham and Women's Hospital, Inc.
    Inventors: Michael W. Epperly, Joel S. Greenberger, Peter Wipf, Julianne Glowacki
  • COMPOUNDS FOR BONE HEALING
    Publication number: 20180185322
    Abstract: Disclosed herein are embodiments of a method of accelerating bone healing in a subject in need thereof, comprising administering to the subject a compound disclosed here. The method may further comprise selecting or identifying a subject that has bone damage, or is a risk of developing bone damage. The compound may be administered after bone damage has occurred, or it may be administered prophylactically. The compound may be administered to a subject that has not and/or will not be exposed to radiation. In other embodiments, the subject has been and/or will be exposed to radiation.
    Type: Application
    Filed: February 27, 2018
    Publication date: July 5, 2018
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, Brigham and Women's Hospital, Inc.
    Inventors: Michael W. Epperly, Joel S. Greenberger, Peter Wipf, Julianne Glowacki
  • Use of targeted nitroxide agents in bone healing
    Patent number: 8748369
    Abstract: Provided herein are compositions and related methods useful for accelerating bone healing and growth. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: June 10, 2014
    Assignee: University of Pittsburgh-Of the Commonwealth System of Higher Education
    Inventors: Michael W. Epperly, Abhay Sudhir Gokhale, Joel S. Greenberger, Peter Wipf, Julianne Glowacki
  • USE OF TARGETED NITROXIDE AGENTS IN BONE HEALING
    Publication number: 20120252733
    Abstract: Provided herein are compositions and related methods useful for accelerating bone healing and growth. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity.
    Type: Application
    Filed: June 4, 2010
    Publication date: October 4, 2012
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Michael W. Epperly, Abhay Sudhir Gokhale, Joel S. Greenberger, Peter Wipf, Julianne Glowacki
  • Delivery system for controlled release of bioactive factors
    Patent number: 5545409
    Abstract: A composition and method for controlled release of water-soluble proteins comprising a surface-eroding polymer matrix and water-soluble bioactive factors is described. The composition bioerodes in the biological environment of the subject at a controlled rate, thereby releasing the water soluble proteins at a rate which allows them to interact with local cell populations.
    Type: Grant
    Filed: April 5, 1994
    Date of Patent: August 13, 1996
    Assignee: Massachusetts Institute of Technology
    Inventors: Cato T. Laurencin, Paul A. Lucas, Glenn T. Syftestad, Abraham Domb, Julianne Glowacki, Robert S. Langer
  • Delivery system for controlled release of bioactive factors
    Patent number: 5356630
    Abstract: A composition and method for controlled release of water-soluble proteins comprising a surface-eroding polymer matrix and water-soluble bioactive factors is described. The composition bioerodes in the biological environment of the subject at a controlled rate, thereby releasing the water soluble proteins at a rate which allows them to interact with local cell populations.
    Type: Grant
    Filed: May 7, 1993
    Date of Patent: October 18, 1994
    Assignee: Massachusetts Institute of Technology
    Inventors: Cato T. Laurencin, Paul A. Lucas, Glenn T. Syftestad, Abraham Domb, Julianne Glowacki, Robert S. Langer
  • Osteogenic composition and method
    Patent number: 4440750
    Abstract: A plastic dispersion of demineralized bone powder and reconstituted native atelopeptide collagen fibers in a continuous aqueous phase having a substantially physiologic pH and ionic strength is used to repair or construct bone by injecting or implanting it at the repair or construction site. Once emplaced the dispersion induces rapid and complete osteogenesis at the site.
    Type: Grant
    Filed: February 12, 1982
    Date of Patent: April 3, 1984
    Assignees: Collagen Corporation, President and Fellows of Harvard College
    Inventors: Julianne Glowacki, Bruce B. Pharriss