Patents by Inventor Julie A. Rood

Julie A. Rood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotides and polypeptides associated with benign prostatic hypertrophy
    Patent number: 6048963
    Abstract: Benign prostatic hypertrophy specific polynucleotides and polypeptides are provided. Methods of diagnosing benign prostatic hypertrophy using these polynucleotides and polypeptides are also provided. Human BPH1 polypeptides and DNA (RNA) encoding such BPH1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such BPH1 for the treatment of prostate disease. Antagonists against such BPH1 and their use as a therapeutic to treat prostate disease are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the BPH1 and for detecting altered levels of the polypeptide in a host.
    Type: Grant
    Filed: November 6, 1998
    Date of Patent: April 11, 2000
    Assignee: SmithKline Beecham Corporation
    Inventor: Julie A. Rood
  • Polynucleotides and polypeptides associated with benign prostatic hypertrophy
    Patent number: 5889145
    Abstract: Benign prostatic hypertrophy specific polynucleotides and polypeptides are provided. Methods of diagnosing benign prostatic hypertrophy using these polynucleotides and polypeptides are also provided. Human BPH1 polypeptides and DNA (RNA) encoding such BPH1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such BPH1 for the treatment of prostate disease. Antagonists against such BPH1 and their use as a therapeutic to treat prostate disease are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the BPH1 and for detecting altered levels of the polypeptide in a host.
    Type: Grant
    Filed: June 19, 1998
    Date of Patent: March 30, 1999
    Assignee: Smithkline Beecham Corporation
    Inventor: Julie A. Rood
  • Cathepsin K gene
    Patent number: 5861298
    Abstract: The invention relates to cathepsin K polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.
    Type: Grant
    Filed: May 7, 1997
    Date of Patent: January 19, 1999
    Assignees: SmithKline Beecham Corporation, Human Genome SciencesInc
    Inventors: Mark D. Adams, Judith A. Blake, Christine M. Debouck, Fred H. Drake, Lisa M. Fitzgerald, Claire M. Fraser, Maxine Gowen, Gregg A. Hastings, Ewen F. Kirkness, Norman H. Lee, Julie Rood
  • Polynucleotides and polypeptides associated with benign prostatic hypertrophy
    Patent number: 5817481
    Abstract: Benign prostatic hypertrophy specific polynucleotides and polypeptides are provided. Methods of diagnosing benign prostatic hypertrophy using these polynucleotides and polypeptides are also provided. Human BPH1 polypeptides and DNA (RNA) encoding such BPH1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such BPH1 for the treatment of prostate disease. Antagonists against such BPH1 and their use as a therapeutic to treat prostate disease are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the BPH1 and for detecting altered levels of the polypeptide in a host.
    Type: Grant
    Filed: May 9, 1997
    Date of Patent: October 6, 1998
    Assignee: SmithKline Beecham Corporation
    Inventor: Julie A. Rood