Abstract: The invention provides a natural killer (NK) cell engineered to express a chimeric antigen receptor (CAR), wherein the CAR comprises the extracellular domain of CD27 or a CD70-binding portion thereof, as well as compositions comprising the engineered NK cell, methods for producing the engineered NK cell, and therapeutic applications of the engineered NK cell, such as for treating neoplastic diseases.

Abstract: A velcro athletic belt with velcro backed clips for securing a workout towel to the torso of a person. This “hands free” belt, clip and towel assembly allows the person to exercise, jog, run or lounge with the towel securely attached on his waist. A different embodiment utilizes clips which attach the towel directly to the person's clothes.

Abstract: A nail polish applicator utilizing a tapered, absorbable, foam tip so that nail polish may be applied more precisely, more uniformly and with less mess. The angular, fine-lined edge allows for precise application of nail polish around the curvatures of the cuticle area. The soft, pliable cell structure of the foam tip readily conforms to the contours of the nail during the polish application and, thereby, paints the nail without leaving any brush marks. Additionally, the absorbable nature of the foam tip allows the polish to stay on the tip better with less dripping or mess. Other embodiments of this invention utilize variations of angular-edged applicators for more precise nail polish application.

Abstract: A cooling garment for dogs to aid in the prevention of heatstroke during hot weather walks. The cooling garment containing a bladder for water, whereby, the cooling garment may be easily stored and frozen in the freezer prior to use. The underside of the cooling garment containing a means to adhere to the dog's coat so the cooling garment stays situated on the back and sides of the dog during warm weather walks and exercise. A sun reflective surface may, additionally, be utilized to further aid in cooling the animal.

Abstract: A beauty pillow contains at least one open or concave area incorporated in a surface thereof. The area is shaped and dimensioned for a person to rest a region of delicate facial tissue thereover, and further is contoured not to touch or rub against the region of delicate facial tissue during normal usage. The pillow surrounding the open or concave area supports the bony structures of the skull and jaw, so that regions of delicate facial tissue remain unstressed and not wrinkled, especially during sleep.

Abstract: A hat or cap has a crown, and possibly also a brim or visor, which is made of a decoratively rigid or semi-rigid material, such as metal or plastic. The airy, mesh-type head covering enables air to circulate within the hat while still enabling a stylish coiffure to be fully visible while the hat is being worn.

Abstract: A first part of the inventive instrument comprises an insertion and removal device in the form of a maneuverable catheter which may be inserted through the mouth or nostril, pharynx, and esophagus into the stomach. In one form, the catheter includes an outer sheath which protects the human body while a tool extending coaxially through an inner sheath is being manipulated. The tool includes a remotely operated pair of tweezers for holding or releasing a loop on insertion or seizing and holding the loop on removal of the second part of the inventive instrument. An alternate device for capturing and holding the second part of the inventive instrument uses an electromagnet. The second part of the inventive instrument comprises a self-compressing, open-ended, balloon-like tube for implantation in and lining of the digestive tract, especially in the intestine, to prevent food from being absorbed into the villi.

Abstract: A personal appliance comprises a vacuum chamber and a steam-generating chamber. Steam or other heat is applied to an area of human skin for a period which is long enough to open pores, melt any wax-like substances within the pores, and otherwise cause the skin to be cleaned. Thereafter, a mild suction is applied to the steamed area which lifts the softened debris out of the open skin pores. In some instances the suction may be applied in a pulsating manner to massage the skin.

Abstract: A decorative personal electric heating appliance has an exterior covering in the form of a stuffed animal, doll, novelty item, etc. having a predetermined appearance, texture or feel which is psychologically attractive and cuddly. The exterior covering encloses an internal fluid-containing bladder having a fill opening. An electric immersion heater means is provided in the bladder for heating the fluid. The stopper for the bladder fill opening and the electrical connector for the electric heater are located recesses in the exterior covering covered by childproof caps camouflaged to blend in with the exterior covering. A temperature indicator is provided on the exterior covering to indicate the temperature of the appliance. The bladder may be emptied and refilled with a cold medium to enable the appliance to be used for cooling if desired.

Abstract: A personal appliance comprises a vacuum chamber and a steam-generating chamber. Steam is applied to an area of human skin for a period which is long enough to open pores, melt any wax-like substances within the pores, and otherwise cause the skin to be cleaned. Thereafter, a mild suction is applied to the steamed area. In some instances the suction may be applied in a pulsating manner to massage the skin.

Abstract: A first part of the inventive instrument comprises an insertion and removal device in the form of a catheter which may be inserted through the mouth, pharynx, and esophagus into the stomach. The catheter includes an outer sheath which protects the human body while a tool extending coaxially through an inner sheath is being manipulated. The tool includes a remotely operated pair of tweezers for holding or releasing a loop on insertion or seizing and holding the loop on removal of the second part of the inventive instrument. The second part of the instrument comprises a tube for implantation in the small intestine. While it is so implanted, the tube prevents food from being there absorbed by the body. The tube may be used to treat obesity or alcoholism, or to cover an ulcer and give it an opportunity to heal without exposure to digesting food.