Patents by Inventor Julie C. Liu

Julie C. Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEIN-BASED ADHESIVE AND ITS MODIFICATION
    Publication number: 20210207013
    Abstract: This invention relates to protein-based adhesives that are capable to adhere to a substrate in a dry, wet, moist, or an aqueous environment. Particularly, said adhesives comprise a crosslinking agent and an elastin-like polypeptide (ELP) that contain tyrosine, lysine, cysteine, dihydroxyphenylalanine (DOPA) or trihydroxyphenylalanine (TOPA) amino acid residue, or a combination thereof, on the polypeptide chain of said ELP. Among others, the adhesives disclosed herein may find broad applications in medical treatments and surgical operations. Compositions and methods of use are within the scope of this application.
    Type: Application
    Filed: August 22, 2019
    Publication date: July 8, 2021
    Applicant: Purdue Research Foundation
    Inventors: Julie C. Liu, Sydney E. Hollingshead, Charng-yu Lin, Jonathan J. Wilker
  • Protein-based adhesives
    Patent number: 10351743
    Abstract: Protein-based adhesives. In one embodiment of the present disclosure, an elastin-like polypeptide has a sequence LDGTL-(PGX1GVPGKGVPGX2GVPGX1GVPGX3GVPGX2GV)n-PVADRGMRLE, wherein each X1 is selected from the group consisting of tyrosine (Y), dihydroxyphenylalanine (DOPA), and 3,4,5-trihydroxyphenylalanine (TOPA), wherein each X2 is selected from the group consisting of valine (V), Y, DOPA, and TOPA, wherein each X3 is selected from the group consisting of glutamic acid (E) and lysine (K), and wherein n is at or between 6 and 10 or higher or lower.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: July 16, 2019
    Assignee: Purdue Research Foundation
    Inventors: Julie C. Liu, Jonathan James Wilker, Mary Jane Brennan, Charng-yu Lin
  • PROTEIN-BASED ADHESIVES
    Publication number: 20170015885
    Abstract: Protein-based adhesives. In one embodiment of the present disclosure, an elastin-like polypeptide has a sequence LDGTL-(PGX1GVPGKGVPGX2GVPGX1GVPGX3GVPGX2GV)n-PVADRGMRLE, wherein each X1 is selected from the group consisting of tyrosine (Y), dihydroxyphenylalanine (DOPA), and 3,4,5-trihydroxyphenylalanine (TOPA), wherein each X2 is selected from the group consisting of valine (V), Y, DOPA, and TOPA, wherein each X3 is selected from the group consisting of glutamic acid (E) and lysine (K), and wherein n is at or between 6 and 10 or higher or lower.
    Type: Application
    Filed: August 8, 2016
    Publication date: January 19, 2017
    Inventors: Julie C. Liu, Jonathan James Wilker, Mary Jane Brennan, Chang-yu Lin
  • PROTEIN-BASED ADHESIVES
    Publication number: 20170015884
    Abstract: Protein-based adhesives. In one embodiment of the present disclosure, an elastin-like polypeptide has a sequence LDGTL-(PGX1GVPGKGVPGX2GVPGX1GVPGX3GVPGX2GV)n-PVADRGMRLE, wherein each X1 is selected from the group consisting of tyrosine (Y), dihydroxyphenylalanine (DOPA), and 3,4,5-trihydroxyphenylalanine (TOPA), wherein each X2 is selected from the group consisting of valine (V), Y, DOPA, and TOPA, wherein each X3 is selected from the group consisting of glutamic acid (E) and lysine (K), and wherein n is at or between 6 and 10 or higher or lower.
    Type: Application
    Filed: July 15, 2016
    Publication date: January 19, 2017
    Inventors: Julie C. Liu, Jonathan James Wilker, Mary Jane Brennan, Charng-yu Lin