Patents by Inventor Julie Dyall

Julie Dyall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF MODELING IN VIVO EFFICACY OF DRUG COMBINATIONS FOR TREATMENT OF VIRAL INFECTIONS
    Publication number: 20240127967
    Abstract: Methods of modeling the in vivo efficacy of drug combinations for the treatment or prevention of viral infection are described. The described methods combine data for single drugs and drug combinations from pharmacokinetic, pharmacodynamic, and viral dynamics models under a series of estimated in vivo drug potencies to provide predictions of the in vivo effects of the drug combinations. These predictions can be used to more accurately select drugs and drug treatment regimens that can be successful in controlling viral infection in animal studies, clinical trials and in medical or veterinary interventions. Also described is a method of treating or preventing filovirus infections using combinations of orally available drugs based on predictions from the modeling methods.
    Type: Application
    Filed: February 9, 2022
    Publication date: April 18, 2024
    Applicants: University of Virginia Patent Foundation, Fred Hutchinson Cancer Research Center
    Inventors: Judith M. White, Shuang Xu, Joshua T. Schiffer, Gene G. Olinger, Courtney L. Finch, Julie Dyall, Stephen J. Polyak, Lisa Johansen
  • 4-AMINOQUINOLINE COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS
    Publication number: 20090221624
    Abstract: This invention is directed to aminoquinoline compounds, pharmaceutical compositions of such compounds, kits comprising such compounds, and uses of such compounds for preparing medicaments and treating virus-related conditions in animals.
    Type: Application
    Filed: May 4, 2006
    Publication date: September 3, 2009
    Inventors: Paul D. Olivo, Benjamin A. Buscher, Julie Dyall, Jennifer I. Jocket-Balsarotti, Andrew K. O'Guin, Robert M. Roth, Yi Zhou, Gary W. Franklin, Gale W. Starkey
  • Multiple viral replicon culture systems
    Publication number: 20050250105
    Abstract: Methods and compositions are provided for screening candidate antiviral agents using cells containing subgenomic viral replication systems such as replicons and minigenomes. The methods involve the simultaneous assay of more than one subgenomic viral replication system. Compositions useful for these methods are also provided.
    Type: Application
    Filed: March 25, 2004
    Publication date: November 10, 2005
    Inventors: Julie Dyall, Charles Romano, Paul Olivo, Robert Roth
  • Method of discovery and development of broad-spectrum antiviral drugs
    Publication number: 20050164167
    Abstract: Method for identifying a broad-spectrum antiviral lead compound. Also methods for marketing and delivering a broad-spectrum antiviral compound and methods for treating patients with antiviral infections with a broad-spectrum antiviral drug are disclosed.
    Type: Application
    Filed: January 28, 2004
    Publication date: July 28, 2005
    Inventors: Benjamin Buscher, Julie Dyall, Jennifer Jockel-Balsarotti, Andrew O'Guin, Paul Olivo, Robert Roth, Yi Zhou
  • Multiple viral replicon culture systems
    Patent number: 6750009
    Abstract: Methods and compositions are provided for screening candidate antiviral agents using cells containing subgenomic viral replication systems such as replicons and minigenomes. The methods involve the simultaneous assay of more than one subgenomic viral replication system. Compositions useful for these methods are also provided.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: June 15, 2004
    Assignee: Apath, LLC
    Inventors: Julie Dyall, Charles P. Romano, Paul D. Olivo, Robert M. Roth
  • Multiple viral replicon culture systems
    Publication number: 20030152912
    Abstract: Methods and compositions are provided for screening candidate antiviral agents using cells containing subgenomic viral replication systems such as replicons and minigenomes. The methods involve the simultaneous assay of more than one subgenomic viral replication system. Compositions useful for these methods are also provided.
    Type: Application
    Filed: January 29, 2002
    Publication date: August 14, 2003
    Inventors: Julie Dyall, Charles P. Romano, Paul D. Olivo, Robert M. Roth