Patents by Inventor Julie Ellen Takacs

Julie Ellen Takacs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IDENTIFICATION AND USE OF COMPOUNDS THAT AFFECT THE FIDELITY OF EUKARYOTIC TRANSLATION INITIATION CODON SELECTION
    Publication number: 20150025044
    Abstract: A screening method for identifying compounds that alter the fidelity with which the initiation codon in mRNAs is recognized by the translational apparatus in eukaryotes is disclosed. This screening method was used to identify compounds having such activity. Methods of altering the fidelity of initiation codon selection are also disclosed. Methods of treating disorders characterized by single nucleotide mutations in initiation codons using compounds identified by the screening method, as well as methods of treating fungal and parasitic infections and hyperproliferative disorders using compounds identified by the screening method are also disclosed.
    Type: Application
    Filed: June 30, 2014
    Publication date: January 22, 2015
    Inventors: Jon R. Lorsch, Julie Ellen Takacs, Timothy Brian Neary
  • Identification and use of compounds that affect the fidelity of eukaryotic translation initiation codon selection
    Patent number: 8828976
    Abstract: A screening method for identifying compounds that alter the fidelity with which the initiation codon in mRNAs is recognized by the translational apparatus in eukaryotes is disclosed. This screening method was used to identify compounds having such activity. Methods of altering the fidelity of initiation codon selection are also disclosed. Methods of treating disorders characterized by single nucleotide mutations in initiation codons using compounds identified by the screening method, as well as methods of treating fungal and parasitic infections and hyperproliferative disorders using compounds identified by the screening method are also disclosed.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: September 9, 2014
    Assignee: The Johns Hopkins University
    Inventors: Jon R. Lorsch, Julie Ellen Takacs, Timothy Brian Neary
  • IDENTIFICATION AND USE OF COMPOUNDS THAT AFFECT THE FIDELITY OF EUKARYOTIC TRANSLATION INITIATION CODON SELECTION
    Publication number: 20110230451
    Abstract: A screening method for identifying compounds that alter the fidelity with which the initiation codon in mRNAs is recognized by the translational apparatus in eukaryotes is disclosed. This screening method was used to identify compounds having such activity. Methods of altering the fidelity of initiation codon selection are also disclosed. Methods of treating disorders characterized by single nucleotide mutations in initiation codons using compounds identified by the screening method, as well as methods of treating fungal and parasitic infections and hyperproliferative disorders using compounds identified by the screening method are also disclosed.
    Type: Application
    Filed: March 18, 2011
    Publication date: September 22, 2011
    Applicant: The Johns Hopkins University
    Inventors: Jon R. Lorsch, Julie Ellen Takacs, Timothy Brian Neary