Abstract: A method and system for processing of physiological signals is provided. The system processes information signals in subband-domain associated with the physiological signals in time-domain. The information signals are obtained by one or more over-sampled filterbanks. The method and system possibly synthesizes the subband signals obtained by subband processing. The method and system may implement the analysis, subband processing, and synthesis algorithms on over-sampled filterbanks, which are implemented on ultra low-power, small size, and low-cost platform in real-time. The method and system may use over-sampled, Weighted-Overlap Add (WOLA) filterbanks.

Abstract: The present invention provides a method for identifying a subject having a risk of developing obesity, coronary microvasular dysfunction, or hypertension, comprising detection of the presence of a single nucleotide polymorphism (SNP) in a nucleic acid encoding an element of at least one &bgr;-adrenergic receptor from the subject. The presence of the SNP is correlated with obesity, coronary microvascular dysfunction, or hypertension, and thereby identifies the subject as having a risk of developing obesity, coronary microvascular dysfunction, of hypertension. The subject invention also provides methods of identifying patients likely to benefit from the prescription of beta blocker hypertension medications. In various embodiments, the nucleic acids detected include those genes encoding ADRB1 (&bgr;1AR), ADRB2 (&bgr;2AR), ADRB3 (&bgr;3AR), GNB3 (G protein &bgr;3 subunit), or GNAS1 (Gs protien alpha subunit). Methods of treating identified individuals are also provided.

Abstract: The present invention provides a method for identifying a subject having a risk of developing obesity, coronary microvascular dysfunction, or hypertension, comprising detection of the presence of a single nucleotide polymorphism (SNP) in a nucleic acid encoding an element of at least one &bgr;-adrenergic receptor from the subject. The presence of the SNP is correlated with obesity, coronary microvascular dysfunction, or hypertension, and thereby identifies the subject as having a risk of developing obesity, coronary microvascular dysfunction, or hypertension. The subject invention also provides methods of identifying patients likely to benefit from the prescription of beta blocker hypertension medications. In various embodiments, the nucleic acids detected include those genes encoding ADRB1 (&bgr;1AR), ADRB2 (&bgr;2AR), ADRB3 (&bgr;3AR), GNB3 (G protein &bgr;3 subunit), or GNAS1 (GS protein alpha subunit). Methods of treating identified individuals are also provided.