Abstract: Techniques are provided to identify, correct, and/or replace anomalous pixels. In one example, a method includes receiving an image frame comprising a plurality of pixels arranged in a plurality of rows and columns. The pixels comprise image data associated with a scene and fixed pattern noise introduced by an imaging device. The method also includes performing a first process on a first set of the pixels to determine associated correction terms configured to reduce the fixed pattern noise, and applying the correction terms to the first set of the pixels in response to the first process. The method also includes performing a second process on a second set of the pixels to determine whether to replace the second set of the pixels to reduce the fixed pattern noise, and replacing at least a subset of the second set of the pixels in response to the second process. Additional methods and systems are also provided.

Abstract: Disclosed are puncture sealing systems and methods of locating a puncture site within a vessel. The systems can include puncture locating dilators and access sheaths that are configured to locate the puncture site within a vessel so that the position of the puncture site relative to a distal end of the access sheath is known during a puncture sealing procedure.

Abstract: Disclosed are puncture sealing systems and methods of locating a puncture site within a vessel. The systems can include puncture locating dilators and access sheaths that are configured to locate the puncture site within a vessel so that the position of the puncture site relative to a distal end of the access sheath is known during a puncture sealing procedure.

Abstract: Disclosed are puncture sealing systems and methods of locating a puncture site within a vessel. The systems can include puncture locating dilators and access sheaths that are configured to locate the puncture site within a vessel so that the position of the puncture site relative to a distal end of the access sheath is known during a puncture sealing procedure.

Abstract: Disclosed are puncture sealing systems and methods of locating a puncture site within a vessel. The systems can include puncture locating dilators and access sheaths that are configured to locate the puncture site within a vessel so that the position of the puncture site relative to a distal end of the access sheath is known during a puncture sealing procedure.

Abstract: Disclosed are puncture sealing systems and methods of locating a puncture site within a vessel. The systems can include puncture locating dilators and access sheaths that are configured to locate the puncture site within a vessel so that the position of the puncture site relative to a distal end of the access sheath is known during a puncture sealing procedure.

Abstract: A method of treating primary focal segmental glomerulosclerosis in a patient having an APOL1 variant, comprising intravenously administering a TGF? antagonist to the patient.

Abstract: Disclosed are puncture sealing systems and methods of locating a puncture site within a vessel. The systems can include puncture locating dilators and access sheaths that are configured to locate the puncture site within a vessel so that the position of the puncture site relative to a distal end of the access sheath is known during a puncture sealing procedure.

Abstract: Disclosed are puncture sealing systems and methods of locating a puncture site within a vessel. The systems can include puncture locating dilators and access sheaths that are configured to locate the puncture site within a vessel so that the position of the puncture site relative to a distal end of the access sheath is known during a puncture sealing procedure.

Abstract: Disclosed are puncture sealing systems and methods of locating a puncture site within a vessel. The systems can include puncture locating dilators and access sheaths that are configured to locate the puncture site within a vessel so that the position of the puncture site relative to a distal end of the access sheath is known during a puncture sealing procedure.

Abstract: A system for managing electronic receipts is provided. According to one aspect, the system includes a portable device, a base device, a user device and an electronic receipts administration system. The electronic receipts administration system provides the base device with the appropriate data to allow the base device to generate, store and manage electronic receipts accordingly. A user uses the portable device to conduct a transaction with the base device. The base device uses a variety of information to generate an electronic receipt for the transaction. Such information includes, for example, information stored on the portable device, information stored locally on the base device and information stored on another device such as an electronic cash register. The electronic receipt is then stored on the portable device. The user device allows the user to subsequently retrieve the electronic receipt for management purposes.

Abstract: An application portal selectively provides a user selective access to data. A data access layer is included in the portal and includes a map associating the user with a permission and further associating a combination of the user and the permission with a data entity, whereby it may be determined whether the user is permitted to access data identified with the data entity. A data stage included in the portal selectively undergoes a synchronization with a remote data store, the synchronization providing data access information that is used to update the map.

Abstract: Disclosed are puncture sealing systems and methods of locating a puncture site within a vessel. The systems can include puncture locating dilators and access sheaths that are configured to locate the puncture site within a vessel so that the position of the puncture site relative to a distal end of the access sheath is known during a puncture sealing procedure.

Abstract: A system for managing electronic receipts is provided. According to one aspect, the system includes a portable device, a base device, a user device and an electronic receipts administration system. The electronic receipts administration system provides the base device with the appropriate data to allow the base device to generate, store and manage electronic receipts accordingly. A user uses the portable device to conduct a transaction with the base device. The base device uses a variety of information to generate an electronic receipt for the transaction. Such information includes, for example, information stored on the portable device, information stored locally on the base device and information stored on another device such as an electronic cash register. The electronic receipt is then stored on the portable device. The user device allows the user to subsequently retrieve the electronic receipt for management purposes.

Abstract: A system for managing electronic receipts is provided. According to one aspect, the system includes a portable device, a base device, a user device and an electronic receipts administration system. The electronic receipts administration system provides the base device with the appropriate data to allow the base device to generate, store and manage electronic receipts accordingly. A user uses the portable device to conduct a transaction with the base device. The base device uses a variety of information to generate an electronic receipt for the transaction. Such information includes, for example, information stored on the portable device, information stored locally on the base device and information stored on another device such as an electronic cash register. The electronic receipt is then stored on the portable device. The user device allows the user to subsequently retrieve the electronic receipt for management purposes.

Abstract: A system may include a data store storing global data mapped from local data maintained by a plurality of heterogeneous data subsystems. The system may further include a life cycle coordinator including a global data life cycle model defining at least one life cycle for the global data, said life cycle coordinator being configured to receive a data update message defined in accordance with the global data life cycle model and representative of an update of the local data of one of the heterogeneous data subsystems, the data update message including a life cycle status identifier of a data record associated with the update, translate the data update message to at least one global data operation, the translation being based at least in part on the life cycle status identifier, and apply the update to the global data by performing the at least one global data operation.

Abstract: In one of many possible embodiments, an exemplary system includes a data integration subsystem including at least one base hierarchical data structure representative of a first set of one or more data relationships. The system further includes a customization subsystem configured to receive one or more commands from an external source. The commands represent a second set of one or more data relationships, the second set of data relationships being externally defined. The customization subsystem is further configured to generate, based on the commands, a custom hierarchical data structure representative of the second set of data relationships, the second hierarchical data structure being generated on top of at least a subset of the base hierarchical data structure.

Abstract: An integration portal provides a user with access to application entities of a plurality of remote applications. An authorization layer included in the integration portal includes a permission map indicating an association between the user and at least one of the application entities of the plurality of remote applications that the user is permitted to access. The authorization layer in the integration portal is synchronized with an authorization layer included in an application portal that provides the user with access to a subset of the remote applications, whereby the permission map is updated with information about at least one of the application entities that the user is permitted to access through the integration portal. Corresponding systems and methods are also disclosed.

Abstract: A system may include a data store storing global data mapped from local data maintained by a plurality of heterogeneous data subsystems.

Abstract: An exemplary system includes a plurality of heterogeneous data subsystems maintaining local data and a coordinator subsystem configured to maintain global data mapped from the local data. The coordinator subsystem includes a global data life cycle model defining at least one life cycle for the global data. The coordinator subsystem is configured to use the global data life cycle model to coordinate a data update between the global data and the local data. In certain implementations, the coordinator subsystem and the heterogeneous data subsystems are configured to communicate using at least one data update message representative of the data update, the data update message being defined in accordance with the global data life cycle model. In certain implementations, the data update message includes a life cycle status identifier associated with the data update.