Patents by Inventor Julie Maurina-Brunker

Julie Maurina-Brunker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150299732
    Abstract: A recombinant yeast that makes an isoprenoid compound is provided. The yeast comprises an endogenous mevalonate pathway comprising (i) an enzyme that converts acetyl-CoA to acetoacetyl-CoA, (ii) an enzyme that converts acetoacetyl-CoA to hydroxymethylglutaryl-CoA, (iii) an enzyme that converts hydroxymethylglutaryl-CoA to mevalonic acid, (iv) an enzyme that converts mevalonic acid to phosphomevalonic acid, (v) an enzyme that converts phosphomevalonic acid to phosphomevalonate, and (vi) an enzyme that converts phosphomevalonate to isopentenyl pyrophosphate. The yeast further comprises heterologous nucleic acid sequences encoding an enzyme that converts hydroxymethylglutaryl-CoA to mevalonic acid, an enzyme that converts mevalonic acid to phosphomevalonic acid, an enzyme that converts phosphomevalonic acid to phosphomevalonate, and an enzyme that converts phosphomevalonate to isopentenyl pyrophosphate.
    Type: Application
    Filed: June 30, 2015
    Publication date: October 22, 2015
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 9102954
    Abstract: A recombinant yeast that makes an isoprenoid compound is provided. The yeast comprises an endogenous mevalonate pathway comprising (i) an enzyme that converts acetyl-CoA to acetoacetyl-CoA, (ii) an enzyme that converts acetoacetyl-CoA to hydroxymethylglutaryl-CoA, (iii) an enzyme that converts hydroxymethylglutaryl-CoA to mevalonic acid, (iv) an enzyme that converts mevalonic acid to phosphomevalonic acid, (v) an enzyme that converts phosphomevalonic acid to phosphomevalonate, and (vi) an enzyme that converts phosphomevalonate to isopentenyl pyrophosphate. The yeast further comprises heterologous nucleic acid sequences encoding an enzyme that converts hydroxymethylglutaryl-CoA to mevalonic acid, an enzyme that converts mevalonic acid to phosphomevalonic acid, an enzyme that converts phosphomevalonic acid to phosphomevalonate, and an enzyme that converts phosphomevalonate to isopentenyl pyrophosphate.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: August 11, 2015
    Assignee: Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 8241888
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: August 14, 2012
    Assignee: Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 8236552
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: July 27, 2009
    Date of Patent: August 7, 2012
    Assignee: Arkion Life Sciences
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Publication number: 20110195470
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Application
    Filed: April 18, 2011
    Publication date: August 11, 2011
    Applicant: ARKION LIFE SCIENCES, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7927862
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: April 19, 2011
    Assignee: Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7927861
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: April 19, 2011
    Assignee: Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Publication number: 20110059516
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Application
    Filed: November 9, 2010
    Publication date: March 10, 2011
    Inventors: JAMES R. MILLIS, JULIE MAURINA-BRUNKER, THOMAS W. MCMULLIN
  • Publication number: 20110059515
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Application
    Filed: November 9, 2010
    Publication date: March 10, 2011
    Inventors: JAMES R. MILLIS, JULIE MAURINA-BRUNKER, THOMAS W. MCMULLIN
  • Patent number: 7842497
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: November 30, 2010
    Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7838279
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: November 23, 2010
    Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7732161
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: June 8, 2010
    Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7718417
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: May 18, 2010
    Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Publication number: 20100035329
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Application
    Filed: July 27, 2009
    Publication date: February 11, 2010
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Publication number: 20070254354
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Application
    Filed: May 24, 2007
    Publication date: November 1, 2007
    Inventors: James Millis, Julie Maurina-Brunker, Thomas McMullin
  • Publication number: 20070238157
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Application
    Filed: May 24, 2007
    Publication date: October 11, 2007
    Inventors: James Millis, Julie Maurina-Brunker, Thomas McMullin
  • Publication number: 20070238159
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Application
    Filed: May 24, 2007
    Publication date: October 11, 2007
    Inventors: James Millis, Julie Maurina-Brunker, Thomas McMullin
  • Publication number: 20070238160
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Application
    Filed: May 24, 2007
    Publication date: October 11, 2007
    Inventors: James Millis, Julie Maurina-Brunker, Thomas McMullin
  • Publication number: 20070231861
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Application
    Filed: May 24, 2007
    Publication date: October 4, 2007
    Inventors: James Millis, Julie Maurina-Brunker, Thomas McMullin
  • Publication number: 20040110257
    Abstract: The invention provides a biological method of producing farnesol or geranylgeraniol.
    Type: Application
    Filed: November 20, 2003
    Publication date: June 10, 2004
    Applicant: Arkion Life Sciences LLC.
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin