Patents by Inventor Julie R. Korenberg

Julie R. Korenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated SH3 genes associates with myeloproliferative disorders and leukemia and uses thereof
    Patent number: 7070954
    Abstract: The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human gene (SH3D1A), some polymorphic alleles of which cause susceptibility to cancers hematopoietic disorders and in particular platelet disorders, Down Syndrome, megakaryocytic disorders and leukemia. More specifically, the invention relates to isolated nucleic acid of the human SH3D1A gene, products, and their use in diagnosis and treatments. The invention further relates to the screening of drugs for cancer therapy. Finally, the invention relates to the screening of the SH3D1A gene for mutations, which are useful for diagnosing the predisposition to hematopoietic disorders.
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: July 4, 2006
    Inventors: Julie R. Korenberg, Xiao-Ning Chen
  • Nucleic acid encoding DS-CAM proteins and products related thereto
    Patent number: 6960656
    Abstract: In accordance with the present invention, there are provided Down Syndrome-Cell Adhesion Molecule (DS-CAM) proteins. Nucleic acid sequences encoding such proteins and assays employing same are also disclosed. The invention DS-CAM proteins can be employed in a variety of ways, for example, for the production of anti-DS-CAM antibodies thereto, in therapeutic compositions and methods employing such proteins and/or antibodies. DS-CAM proteins are also useful in bioassays to identify agonists and antagonists thereto.
    Type: Grant
    Filed: October 23, 1997
    Date of Patent: November 1, 2005
    Assignee: Cedars Sinai Medical Center
    Inventor: Julie R. Korenberg
  • Novel chromosome 21 gene marker, compositions and methods using same
    Publication number: 20040180335
    Abstract: The present invention provides isolated nucleic acids encoding human EHOC-1 protein and isolated receptor proteins encoded thereby. Further provided are vectors containing invention nucleic acids, probes that hybridize thereto, host cells transformed therewith, antisense oligonucleotides thereto and compositions containing, antibodies that specifically bind to invention polypeptides and compositions containing, as well as transgenic non-human mammals that express the invention protein.
    Type: Application
    Filed: December 26, 2000
    Publication date: September 16, 2004
    Inventors: Julie R. Korenberg, Kazuhiro Yamakawa
  • Chromosome 21 gene marker, compositions and methods using same
    Patent number: 6166180
    Abstract: The present invention provides isolated nucleic acids encoding human EHOC-1 protein and isolated receptor proteins encoded thereby. Further provided are vectors containing invention nucleic acids, probes that hybridize thereto, host cells transformed therewith, antisense oligonucleotides thereto and compositions containing, antibodies that specifically bind to invention polypeptides and compositions containing, as well as transgenic non-human mammals that express the invention protein.
    Type: Grant
    Filed: March 26, 1998
    Date of Patent: December 26, 2000
    Assignee: Cedar-Sinai Medical Center
    Inventors: Julie R. Korenberg, Kazuhiro Yamakawa
  • Congenital heart disease proteins and products related thereto
    Patent number: 6040429
    Abstract: In accordance with the present invention, there are provided novel Congenital Heart Disease (CHD) proteins. Nucleic acid sequences encoding such proteins and assays employing same are also disclosed. The invention CHD proteins can be employed in a variety of ways, for example, for the production of anti-CHD antibodies thereto, in therapeutic compositions and methods employing such proteins and/or antibodies.
    Type: Grant
    Filed: August 30, 1999
    Date of Patent: March 21, 2000
    Assignee: Cedars-Sinai Medical Center
    Inventor: Julie R. Korenberg
  • Nucleic acid encoding congenital heart disease protein and products related thereto
    Patent number: 5945305
    Abstract: In accordance with the present invention, there are provided novel Congenital Heart Disease (CHD) proteins. Nucleic acid sequences encoding such proteins and assays employing same are also disclosed. The invention CHD proteins can be employed in a variety of ways, for example, for the production of anti-CHD antibodies thereto, in therapeutic compositions and methods employing such proteins and/or antibodies.
    Type: Grant
    Filed: September 11, 1997
    Date of Patent: August 31, 1999
    Assignee: Cedars-Sinai Medical Center
    Inventor: Julie R. Korenberg
  • Chromosome 21 gene marker, compositions and methods using same
    Patent number: 5773268
    Abstract: The present invention provides isolated nucleic acids encoding human EHOC-1 protein and isolated receptor proteins encoded thereby. Further provided are vectors containing invention nucleic acids, probes that hybridize thereto, host cells transformed therewith, antisense oligonucleotides thereto and compositions containing, antibodies that specifically bind to invention polypeptides and compositions containing, as well as transgenic non-human mammals that express the invention protein.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: June 30, 1998
    Assignee: Cedars-Sinai Medical Center
    Inventors: Julie R. Korenberg, Kazuhiro Yamakawa