Patents by Inventor Julien Barbier

Julien Barbier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Correction of software coding projects
    Patent number: 11636778
    Abstract: A computer-implemented method comprising: receiving a job from a plurality of priority queues, the job including a deliverable and a plurality of commands; performing a correction procedure on the deliverable, wherein the correction procedure comprises, for each of the plurality of commands: transforming a respective command into a structure of keywords, the structure associated with a flow of execution, the structure including a plurality of nodes, the plurality of nodes including a root node and plurality of parent nodes, each parent node of the plurality of parent nodes having at least one child node, each parent node of the plurality of parent nodes including a keyword in the respective command; traversing the structure according to the flow of execution, executing one or more keywords at one or more parent nodes of the plurality of parent nodes; determining an output of the respective command based on the execution of the one or more keywords at the one or more parent nodes of the plurality of parent nod
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: April 25, 2023
    Assignee: Holberton, Inc.
    Inventors: Guillaume Salva, Julien Barbier
  • NEW DIHYDROQUINAZOLINONES EXHIBITING PROTECTIVE ACTIVITY AGAINST INTRACELLULAR-ACTING TOXINS, INTRACELLULAR VIRUSES AND BACTERIA
    Publication number: 20220002289
    Abstract: The invention relates to a new family of compounds of the type 2,3-dihydroquinazolin-4(1H)-one and the use thereof as inhibitors of the toxic effects of intracellular-acting toxins, such as ricin, Shiga toxins or the cholera toxin, using retrograde transport to intoxicate the cells, or viruses or bacteria using retrograde and/or syntaxin 5-dependent transport to infect the cells, specifically viruses or bacteria entering into the cells by means of endocytosis, or intracellular parasites.
    Type: Application
    Filed: November 28, 2019
    Publication date: January 6, 2022
    Applicant: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Jean-Christophe Cintrat, Julien Barbier, Daniel Gillet, Alain Pruvost, Audrey Couhert, Livia Tepshi, Robin Vinck
  • Benzodiazepine derivatives for use in the treatment of Chlamydiales infections
    Patent number: 11136299
    Abstract: The invention relates to a method for treating a Chlamidyales infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: Wherein R1, R2, R3 and Ar are as defined in claim 1.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: October 5, 2021
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Hajer Abdelkafi, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • CORRECTION OF SOFTWARE CODING PROJECTS
    Publication number: 20200327823
    Abstract: A computer-implemented method comprising: receiving a job from a plurality of priority queues, the job including a deliverable and a plurality of commands; performing a correction procedure on the deliverable, wherein the correction procedure comprises, for each of the plurality of commands: transforming a respective command into a structure of keywords, the structure associated with a flow of execution, the structure including a plurality of nodes, the plurality of nodes including a root node and plurality of parent nodes, each parent node of the plurality of parent nodes having at least one child node, each parent node of the plurality of parent nodes including a keyword in the respective command; traversing the structure according to the flow of execution, executing one or more keywords at one or more parent nodes of the plurality of parent nodes; determining an output of the respective command based on the execution of the one or more keywords at the one or more parent nodes of the plurality of parent nod
    Type: Application
    Filed: April 12, 2019
    Publication date: October 15, 2020
    Inventors: Guillaume Salva, Julien Barbier
  • Adamantane or Bicyclic Monoterpenoid Derivatives for Use in the Treatment of Leishmaniasis
    Publication number: 20200281873
    Abstract: The present invention is in the field of therapeutic drugs to treat leishmaniasis. In particular, the invention concerns adamantane and bicyclic monoterpenoid derivatives for use in the treatment of leishmaniasis.
    Type: Application
    Filed: October 31, 2018
    Publication date: September 10, 2020
    Applicants: Commissariat a l'Energie Atomique et aux Energies Alternatives, Université Paris-Sud, Drugabilis
    Inventors: Daniel Gillet, Jean-Christophe Cintrat, Julien Barbier, Alain Pruvost, Philippe Loiseau, Joël Vacus
  • Adamantane or pinene derivatives for use in the treatment of chlamydiales infections
    Patent number: 10039727
    Abstract: The present invention relates to a method for treating a Chlamydiales infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: W-L1-NH-L2-Ar?? (I) Wherein W, L1, L2 and Ar are as defined in claim 1.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: August 7, 2018
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Valérie Pons, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action
    Publication number: 20170233386
    Abstract: The subject matter of the present invention is novel families of compounds which are aromatic amine, imine, aminoadamantane and benzodiazepine derivatives, medicaments comprising same and the use thereof as inhibitors of the toxic effects of toxins with intracellular activity, such as, for example, ricin, and of viruses that use the internalization pathway for infecting cells.
    Type: Application
    Filed: April 24, 2017
    Publication date: August 17, 2017
    Applicant: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Roman Lopez, Séverine Hebbe, Daniel Gillet, Julien Barbier
  • 2,3-dihydroquinazolin-4(1H)-one derivatives for use in the treatment of viral infections
    Patent number: 9675615
    Abstract: Use of 2,3-dihydroquinazolin-4(1H)-one cyclic derivatives of formula (I) for the treatment of infection with viruses entering cells by endocytosis, especially filovirus such as Ebolavirus.
    Type: Grant
    Filed: October 18, 2013
    Date of Patent: June 13, 2017
    Assignees: Commissariat a l'Energie Atomique et aux Energies Alternatives, The Board of Regents of the University of Texas System
    Inventors: Daniel Gillet, Julien Barbier, Robert Davey, Jean-Christophe Cintrat, Romain Noel
  • Quinazolinone derivatives for use in the treatment of chlamydiales infections
    Patent number: 9598406
    Abstract: The present invention relates to a method for treating a Chlamydiae infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: Wherein, R1, R2, R3, R4 and p are as defined in claim 1.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: March 21, 2017
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Karen Hinsinger, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • Compounds having a protective activity against toxins with intracellular activity
    Patent number: 9540356
    Abstract: The present invention concerns a new family of 2,3-dihydroquinazolin-4(1H)-one compounds of general formula (I), and the use thereof as inhibitors of the toxic effects of toxins with intracellular activity, such as ricin or Shiga toxin, for example, using retrograde transport to intoxicate cells.
    Type: Grant
    Filed: October 18, 2013
    Date of Patent: January 10, 2017
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Daniel Gillet, Julien Barbier, Ludger Johannes, Jean-Christophe Cintrat, Romain Noel
  • Adamantane or Pinene Derivatives for Use in the Treatment of Chlamydiales Infections
    Publication number: 20160310448
    Abstract: The present invention relates to a method for treating a Chlamydiales infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: W—L1—NH—L2—Ar??(I) Wherein W, L1, L2 and Ar are as defined in claim 1.
    Type: Application
    Filed: April 20, 2016
    Publication date: October 27, 2016
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Valérie Pons, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • Quinazolinone Derivatives for Use in the Treatment of Chlamydiales Infections
    Publication number: 20160311815
    Abstract: The present invention relates to a method for treating a Chlamydiae infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: Wherein, R1, R2, R3, R4 and p are as defined in claim 1.
    Type: Application
    Filed: April 20, 2016
    Publication date: October 27, 2016
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Karen Hinsinger, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • Benzodiazepine Derivatives for Use in the Treatment of Chlamydiales Infections
    Publication number: 20160311783
    Abstract: The invention relates to a method for treating a Chlamidyales infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: Wherein R1, R2, R3 and Ar are as defined in claim 1.
    Type: Application
    Filed: April 20, 2016
    Publication date: October 27, 2016
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Hajer Abdelkafi, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION
    Publication number: 20160083355
    Abstract: The subject matter of the present invention is novel families of compounds which are aromatic amine, imine, aminoadamantane and benzodiazepine derivatives, medicaments comprising same and the use thereof as inhibitors of the toxic effects of toxins with intracellular activity, such as, for example, ricin, and of viruses that use the internalization pathway for infecting cells.
    Type: Application
    Filed: July 27, 2015
    Publication date: March 24, 2016
    Inventors: Roman Lopez, Severine Hebbe, Daniel Gillet, Julien Barbier
  • NEW COMPOUNDS HAVING A PROTECTIVE ACTIVITY AGAINST TOXINS WITH INTRACELLULAR ACTIVITY
    Publication number: 20150291568
    Abstract: The present invention concerns a new family of 2,3-dihydroquinazolin-4(1H)-one compounds of general formula (I), and the use thereof as inhibitors of the toxic effects of toxins with intracellular activity, such as ricin or Shiga toxin, for example, using retrograde transport to intoxicate cells.
    Type: Application
    Filed: October 18, 2013
    Publication date: October 15, 2015
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Daniel Gillet, Julien Barbier, Ludger Johannes, Jean-Christophe Cintrat, Romain Noel
  • 2,3-DIHYDROQUINAZOLIN-4(1H)-ONE DERIVATIVES FOR USE IN THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20150250788
    Abstract: Use of 2,3-dihydroquinazolin-4(1H)-one cyclic derivatives of formula (I) for the treatment of infection with viruses entering cells by endocytosis, especially filovirus such as Ebolavirus.
    Type: Application
    Filed: October 18, 2013
    Publication date: September 10, 2015
    Applicants: Commissariat A L'energie Atomique Et Aux Energies Alternatives, The Board of Regents of the University of Texas System
    Inventors: Daniel Gillet, Julien Barbier, Robert Davey, Jean-Christophe Cintrat, Romain Noel
  • Inhibitors of the shiga toxins trafficking through the retrograde pathway
    Patent number: 9034868
    Abstract: The present invention relates to the use of compounds of general formula (I) and (II) for the preparation of a drug for preventing and/or treating disorders caused by Shiga toxins and related toxins.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: May 19, 2015
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Daniel Gillet, Julien Barbier, Ludger Johannes, Bahne Stechmann, Siau-Kun Bai
  • INHIBITORS OF THE SHIGA TOXINS TRAFFICKING THROUGH THE RETROGRADE PATHWAY
    Publication number: 20140073633
    Abstract: The present invention relates to the use of compounds of general formula (I) and (II) for the preparation of a drug for preventing and/or treating disorders caused by Shiga toxins and related toxins.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 13, 2014
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENE ALT., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE
    Inventors: Daniel GILLET, Julien BARBIER, Ludger JOHANNES, Bahne STECHMANN, Siau-Kun BAI
  • Inhibitors of the Shiga toxins trafficking through the retrograde pathway
    Patent number: 8609732
    Abstract: The present invention relates to the use of compounds of general formula (I) and (II) for the preparation of a drug for preventing and/or treating disorders caused by Shiga toxins and related toxins.
    Type: Grant
    Filed: June 17, 2009
    Date of Patent: December 17, 2013
    Assignees: Commissariat a l'Energie Atomique et aux Energies Alternatives, Institut Curie, Centre National de la Recherche Scientfique
    Inventors: Daniel Gillet, Julien Barbier, Ludger Johannes, Bahne Stechmann, Siau-Kun Bai
  • Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action
    Publication number: 20120283249
    Abstract: The subject matter of the present invention is novel families of compounds which are aromatic amine, imine, aminoadamantane and benzodiazepine derivatives, medicaments comprising same and the use thereof as inhibitors of the toxic effects of toxins with intracellular activity, such as, for example, ricin, and of viruses that use the internalization pathway for infecting cells.
    Type: Application
    Filed: June 17, 2009
    Publication date: November 8, 2012
    Inventors: Roman Lopez, Séverine Hebbe, Daniel Gillet, Julien Barbier