Abstract: A method for authorizing the flight of an aircraft provided with a hybrid power plant having at least one heat engine and at least one electric motor electrically connected to an electrical energy source comprising several electrical accumulators. The method comprises extracting (STP1), while on the ground, an electrical energy or an electrical power to be extracted from the electrical energy source during a predetermined time period and determining (STP2) for the electrical accumulators, respective initial values of an operating parameter, calculating (STP3) an average value from the initial values, determining (STP4) a minimum value from the measured initial values, issuing an authorization when a difference between the average value and the minimum value is less than a threshold and a prohibition when said difference between the average value and the minimum value is greater than or equal to the threshold.

Abstract: The present invention discloses a conjugate comprising an antigen (for example a saccharide antigen) covalently linked to a Pseudomonas aeruginosa PcrV carrier protein comprising an amino acid sequence which is at least 80% identical to the sequence of SEQ ID NO:1-4, wherein the antigen is linked (either directly or through a linker) to an amino acid residue of the P. aeruginosa PcrV carrier protein. The invention also discloses Pseudomonas aeruginosa PcrV proteins that contain glycosylation site consensus sequences.

Abstract: The present invention relates to the field of modified proteins, immunogenic compositions and vaccines comprising the modified proteins, their manufacture and the use of such compositions in medicine. More particularly, it relates to a modified EPA (Exotoxin A of Pseudomonas aeruginosa) protein. The modified EPA can be used as a carrier protein for other antigens, particularly saccharide antigens or other antigens lacking T cell epitopes.

Abstract: The present disclosure provides mutated PglB oligosaccharyltransferase enzymes that have the ability to efficiently catalyze the transfer of a saccharide from a lipid carrier to an asparagine reissue in a glycosylation motif on a protein. Also provided are polynucleotides encoding the mutated PglB oligosaccharyltransferase enzymes, host cells capable of expressing the engineered PglB oligosaccharyltransferase enzymes, and methods of using the engineered PglB oligosaccharyltransferase enzymes to make N-glycosylated proteins. Also provided are N-glycosylated proteins that are made using the engineered PglB oligosaccharyltransferase enzymes.

Abstract: The present invention discloses a conjugate comprising an antigen (for example a saccharide antigen) covalently linked to a Pseudomonas aeruginosa PcrV carrier protein comprising an amino acid sequence which is at least 80% identical to the sequence of SEQ ID NO:1-4, wherein the antigen is linked (either directly or through a linker) to an amino acid residue of the P. aeruginosa PcrV carrier protein. The invention also discloses Pseudomonas aeruginosa PcrV proteins that contain glycosylation site consensus sequences.

Abstract: A storage shuttle for a flexible intraocular lens injection device. The flexible intraocular lens injection device includes a tubular body having a casing and an axial cavity, a barrel arranged at a distal end of the tubular body and having an ejection cavity in communication with the axial cavity of the tubular body, and a housing in the axial cavity of the tubular body.

Abstract: A flexible intraocular lens injection device, comprising a tubular body that has a casing, a plunger, a barrel having a cross-section that decreases in the opposite direction to the tubular body, and a housing in the axial cavity of the tubular body intended to receive a storage shuttle containing a flexible intraocular lens, the casing of the tubular body having a side opening, so as to allow the insertion of the storage shuttle and in the vicinity of this side opening, the above-mentioned casing carrying a first outwardly-protruding rotary attachment means configured to engage with a second rotary attachment means provided on the storage shuttle, so that, when the two above-mentioned rotary attachment means are engaged, the storage shuttle is able to rotate about an axis of rotation parallel to said axial direction of the axial cavity of the tubular body.

Abstract: A flexible intraocular lens injection device, comprising a tubular body that has a casing, a plunger, a barrel having a cross-section that decreases in the opposite direction to the tubular body, and a housing in the axial cavity of the tubular body intended to receive a storage shuttle containing a flexible intraocular lens, the casing of the tubular body having a side opening, so as to allow the insertion of the storage shuttle and in the vicinity of this side opening, the above-mentioned casing carrying a first outwardly-protruding rotary attachment means configured to engage with a second rotary attachment means provided on the storage shuttle, so that, when the two above-mentioned rotary attachment means are engaged, the storage shuttle is able to rotate about an axis of rotation parallel to said axial direction of the axial cavity of the tubular body.

Abstract: Loudspeaker enclosure comprising at least one loudspeaker having a convex mobile membrane, and a member surrounding the mobile membrane and comprising an external surface bounded by an internal edge (??) situated facing the mobile membrane, which comprises a peripheral edge (?) situated facing the internal edge of the member and forming a closed loop. The mobile membrane and the member have a suitable shape such that, over a continuous portion (??) of the peripheral edge (?) representing at least 25% of the length of the peripheral edge, for any first point (M) on the continuous portion and any second point (M?) situated on the internal edge at a location such that the distance between the first point (M) and second point (M?) is minimal, the mobile membrane has, at the first point, a first tangent plane, essentially coincident with a second tangent plane at the second point.

Abstract: The present invention discloses a conjugate comprising an antigen (for example a saccharide antigen) covalently linked to a Pseudomonas aeruginosa PcrV carrier protein comprising an amino acid sequence which is at least 80% identical to the sequence of SEQ ID NO:1-4, wherein the antigen is linked (either directly or through a linker) to an amino acid residue of the P. aeruginosa PcrV carrier protein. The invention also discloses Pseudomonas aeruginosa PcrV proteins that contain glycosylation site consensus sequences.

Abstract: Loudspeaker enclosure comprising at least one loudspeaker having a convex mobile membrane, and a member surrounding the mobile membrane and comprising an external surface bounded by an internal edge (??)situated facing the mobile membrane, which comprises a peripheral edge (?) situated facing the internal edge of the member and forming a closed loop. The mobile membrane and the member have a suitable shape such that, over a continuous portion (??) of the peripheral edge (?) representing at least 25% of the length of the peripheral edge, for any first point (M) on the continuous portion and any second point (M?) situated on the internal edge at a location such that the distance between the first point (M) and second point (M?) is minimal, the mobile membrane has, at the first point, a first tangent plane, essentially coincident with a second tangent plane at the second point.

Abstract: The method of the invention enables selection of an item (21) from a plurality of items (21, 23, 25). The method comprises the steps of visually representing a selected item (21) and reproducing at least part of an audio segment representing the selected item (21). The method further comprises applying a visual spatial effect to the visual representation of the selected item (21) and applying a spatial audio effect corresponding to the visual spatial effect to the reproduction of the audio segment. The device of the invention comprises electronic circuitry which is operative to perform the method of the invention. The computer program product of the invention enables a programmable device to perform the method of the invention.

Abstract: A speaker arrangement comprises a first sound transducer (101) for reproducing sound in a lower frequency range and having a first on-axis direction and a first center point. The arrangement further comprises a second sound transducer (103) for reproducing sound in a higher frequency range, the second sound transducer (103) being mounted in front of the first sound transducer and having a second on-axis direction and a second center point. The transducers are positioned such that an angle between the first on-axis direction and the second on-axis direction is between 45° and 135°, and such that the distance between the first center point and the second center point is not higher than a cross-over wavelength corresponding to the cross-over frequency. The cross-over frequency between the lower frequency range and the higher frequency range is selected to be within the interval from 1.5 kHz to 3 kHz. An improved point source approximation may be achieved.

Abstract: An audio system receives a multi-channel signal which is fed to a controller (121) that generates a first drive signal for a first sound emitter (111) by combining signals of a plurality of the channels. The first drive signal has a signal component contribution from a first bandwidth of each channel of the multi-channel signal. The multi-channel signal is also fed to another controller (115) which generates second drive signals for second sound emitters (101-109). The second drive signals are generated from a single channel signals of the multi-channel signal and in a second bandwidth having a lower cut-off frequency which is above 950 Hz for a 3 dB gain attenuation relative to an average gain for a frequency band extending 1 kHz above the lower cut-off frequency and higher than a lower cut-off frequency of the first bandwidth. A delay processor (125) introduces a delay for signal components of the first drive signal relative a corresponding second drive signal.

Abstract: A speaker arrangement comprises a first sound transducer (101) for reproducing sound in a lower frequency range and having a first on-axis direction and a first centre point. The arrangement further comprises a second sound transducer (103) for reproducing sound in a higher frequency range, the second sound transducer (103) being mounted in front of the first sound transducer and having a second on-axis direction and a second centre point. The transducers are positioned such that an angle between the first on-axis direction and the second on-axis direction is between 45° and 135°, and such that the distance between the first centre point and the second centre point is not higher than a cross-over wavelength corresponding to the cross-over frequency. The cross-over frequency between the lower frequency range and the higher frequency range is selected to be within the interval from 1.5 kHz to 3 kHz. An improved point source approximation may be achieved.

Abstract: A device (120) for processing data for a wearable apparatus (100, 110), the device (120) comprising an input unit (122) adapted to receive input data, means (124, 116, 117) for generating information, referred to as wearing information (WI), which is based on sensor information and indicates a state, referred to as wearing state, in which the wearable apparatus (100) is worn, and a processing unit (121) adapted to process the input data on the basis of the wearing information (WI), thereby generating output data.

Abstract: An audio system receives a multi-channel signal which is fed to a controller (121) that generates a first drive signal for a first sound emitter (111) by combining signals of a plurality of the channels. The first drive signal has a signal component contribution from a first bandwidth of each channel of the multi-channel signal. The multi-channel signal is also fed to another controller (115) which generates second drive signals for second sound emitters (101-109). The second drive signals are generated from a single channel signals of the multi-channel signal and in a second bandwidth having a lower cut-off frequency which is above 950 Hz for a 3 dB gain attenuation relative to an average gain for a frequency band extending 1 kHz above the lower cut-off frequency and higher than a lower cut-off frequency of the first bandwidth. A delay processor (125) introduces a delay for signal components of the first drive signal relative a corresponding second drive signal.

Abstract: The method of the invention enables selection of an item (21) from a plurality of items (21, 23, 25). The method comprises the steps of visually representing a selected item (21) and reproducing at least part of an audio segment representing the selected item (21). The method further comprises applying a visual spatial effect to the visual representation of the selected item (21) and applying a spatial audio effect corresponding to the visual spatial effect to the reproduction of the audio segment. The device of the invention comprises electronic circuitry which is operative to perform the method of the invention. The computer program product of the invention enables a programmable device to perform the method of the invention.

Abstract: An audio device is arranged to present a plurality of test audio signals to a user where each test audio signal comprises a signal component and a noise component. A user preference processor (109) receives user preference feedback for the test audio signals and generates a personalization parameter for the user in response to the user preference feedback and a noise parameter for the noise component of at least one of the test audio signals. An audio processor (113) then processes an audio signal in response to the personalization parameter and the resulting signal is presented to the user. The invention may allow improved characterization of a user thereby resulting in improved adaptation of the processing and thus an improved personalization of the presented signal. The invention may e.g. be beneficial for hearing aids for hearing impaired users.

Abstract: Headphones or earphones are commonly known as electro-acoustic transducers used by a single listener. The invention relates to combing insert and non-insert electro-acoustic transducers in a headphone element. In this way a combination of a wide-low frequency reproduction (insert type) and a wide-high frequency reproduction (non-insert type) are obtained.