Patents by Inventor JULIEN MEISSONNIER
JULIEN MEISSONNIER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230256447Abstract: A microfluidic apparatus and methods thereof. The Apparatus having a flat and thin substrate, the substrate including at least one microfluidic testing device, each device with: plurality of Stationary Nanoliter Droplet Array (SNDA) components; a common inlet port and a distribution manifold, configured to enable an introduction of a fluid into all the primary channels; plurality of individual inlet ports, each coupled to a different primary channel, configured to enable an individual introduction of a fluid into its associated primary channel; and one or more outlet ports and optionally a collecting manifold, configured to evacuate liquid and/or gas flowing out thereof.Type: ApplicationFiled: July 15, 2021Publication date: August 17, 2023Applicant: Nanosynex LtdInventors: Micha ROSEN, Michelle PATKIN NEHRER, Elad MOR, Julien MEISSONNIER, Jonathan AVESAR, Alexey SHATALOV, Dan DURLACHER
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Patent number: 11703506Abstract: The present invention provides self-contained systems for performing an assay for determining a chemical state, the system including a stationary cartridge for performing the assay therein, at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with said sample to report a result of the assay, wherein the at least one reagent, the sample and the at least one reporter functionality are contained within the cartridge.Type: GrantFiled: August 23, 2020Date of Patent: July 18, 2023Assignee: Accellix Ltd.Inventors: Harvey Lee Kasdan, Julien Meissonnier, Yoav Zuta, Micha Rosen, Yael Himmel, Yehoshua Broder, Bruce Davis, Bruce Goldman, Boaz Giron, Zion Botesazan, Eliezer Blasberg, Ilan Semmel, Jacques Aschkenasy
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Publication number: 20220249468Abstract: The present disclosure is directed to a pharmaceutical formulation intended for oral delivery of synthetic or natural poorly permeable calcitonin gene-related peptide (CGRP) inhibitors or salts/solvates thereof having a therapeutic activity. The pharmaceutical formulation can include a synthetic or natural poorly permeable CGRP inhibitors or salt or solvate thereof in an amount 0.01-10 wt. % of the total weight of the formulation; a lipophilic phase comprising triglycerides of fatty acids in an amount of 50-80 wt. % of the total weight of the formulation; and at least one lipophilic surfactant comprising partial esters of polyol and fatty acids in an amount of about 10-50 wt. % of the total weight of the formulation.Type: ApplicationFiled: April 10, 2020Publication date: August 11, 2022Applicants: R.P. Scherer Technologies, LLC, Biohaven Pharmaceutical Holding Company Ltd.Inventors: Vincent PLASSAT, Benoit HILBOLD, Aurélia GALUS, Thomas POINTEAUX, Julien MEISSONNIER, Gene M. DUBOWCHIK, Charles M. CONWAY
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Publication number: 20220143188Abstract: The present disclosure is directed to a pharmaceutical formulation intended for oral delivery of synthetic or natural poorly permeable molecules or salts/solvates thereof having a therapeutic activity. The pharmaceutical formulation can include a synthetic or natural poorly permeable molecule or salt or solvate thereof in an amount 0.01-10 wt. % of the total weight of the formulation; a lipophilic phase comprising triglycerides of fatty acids in an amount of 50-80 wt. % of the total weight of the formulation; and at least one lipophilic surfactant comprising partial esters of polyol and fatty acids in an amount of about 10-50 wt. % of the total weight of the formulation.Type: ApplicationFiled: November 29, 2021Publication date: May 12, 2022Applicant: R.P. Scherer Technologies, LLCInventors: Vincent PLASSAT, Benoit HILBOLD, Aurélia GALUS, Thomas POINTEAUX, Julien MEISSONNIER
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Patent number: 11185589Abstract: The present disclosure is directed to a pharmaceutical formulation intended for oral delivery of synthetic or natural poorly permeable molecules or salts/solvates thereof having a therapeutic activity. The pharmaceutical formulation can include a synthetic or natural poorly permeable molecule or salt or solvate thereof in an amount 0.01-10 wt. % of the total weight of the formulation; a lipophilic phase comprising triglycerides of fatty acids in an amount of 50-80 wt. % of the total weight of the formulation; and at least one lipophilic surfactant comprising partial esters of polyol and fatty acids in an amount of about 10-50 wt. % of the total weight of the formulation.Type: GrantFiled: April 10, 2020Date of Patent: November 30, 2021Assignee: R.P. Scherer Technologies, LLCInventors: Vincent Plassat, Benoit Hilbold, Aurélia Galus, Thomas Pointeaux, Julien Meissonnier
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Publication number: 20200386756Abstract: The present invention provides self-contained systems for performing an assay for determining a chemical state, the system including a stationary cartridge for performing the assay therein, at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with said sample to report a result of the assay, wherein the at least one reagent, the sample and the at least one reporter functionality are contained within the cartridge.Type: ApplicationFiled: August 23, 2020Publication date: December 10, 2020Applicant: ACCELLIX LTD.Inventors: Harvey Lee KASDAN, Julien MEISSONNIER, Yoav ZUTA, Micha ROSEN, Yael HIMMEL, Yehoshua BRODER, Bruce DAVIS, Bruce GOLDMAN, Boaz GIRON, Zion BOTESAZAN, Eliezer BLASBERG, IIan SEMMEL, Jacques ASCHKENASY
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Publication number: 20200323985Abstract: The present disclosure is directed to a pharmaceutical formulation intended for oral delivery of synthetic or natural poorly permeable molecules or salts/solvates thereof having a therapeutic activity. The pharmaceutical formulation can include a synthetic or natural poorly permeable molecule or salt or solvate thereof in an amount 0.01-10 wt. % of the total weight of the formulation; a lipophilic phase comprising triglycerides of fatty acids in an amount of 50-80 wt. % of the total weight of the formulation; and at least one lipophilic surfactant comprising partial esters of polyol and fatty acids in an amount of about 10-50 wt. % of the total weight of the formulation.Type: ApplicationFiled: April 10, 2020Publication date: October 15, 2020Applicant: R.P. Scherer Technologies, LLCInventors: Vincent PLASSAT, Benoit HILBOLD, Aurélia GALUS, Thomas POINTEAUX, Julien MEISSONNIER
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Patent number: 10761094Abstract: The present invention provides self-contained systems for performing an assay for determining a chemical state, the system including a stationary cartridge for performing the assay therein, at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with said sample to report a result of the assay, wherein the at least one reagent, the sample and the at least one reporter functionality are contained within the cartridge.Type: GrantFiled: June 18, 2018Date of Patent: September 1, 2020Assignee: ACCELLIX LTD.Inventors: Harvey Lee Kasdan, Julien Meissonnier, Yoav Zuta, Micha Rosen, Yael Himmel, Yehoshua Broder, Bruce Davis, Bruce Goldman, Boaz Giron, Zion Botesazan, Ellezer Blasberg, Ilan Semmel, Jacques Aschkenasy
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Patent number: 10610861Abstract: Determining a biological condition in a mammal by using a cartridge, having fluidic open channels, sealable after receiving a fluid specimen, passing any of the specimen through any of the channels, contacting any reagent stored in a chamber with the specimen in a reaction chamber inducing a reaction and forming a reaction product, a mechanical controller including first urging means applying a force externally onto the chamber to release the reagent, second urging means applying a removable force onto the channels thereby inducing fluidic movement in a first direction in the channels and upon removal of the force causing fluidic movement in an opposite direction, alignment means aligning a reading channel on the cartridge for a detection to take place, an optical reader detecting the reaction product in the reading channel, and a processor receiving data from the optical reader and processing the data to determine the biological condition.Type: GrantFiled: December 17, 2013Date of Patent: April 7, 2020Assignee: ACCELLIX LTD.Inventors: Julien Meissonnier, Harvey Lee Kasdan, Yoav Zuta, Bruce Davis, Micha Rosen, Yael Himmel, Yehoshua Broder, Boaz Giron, Zion Botesazan, Eliezer Blasberg, Ilan Semmel, Jacques Aschkenasy, Bruce Goldman
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Publication number: 20180299443Abstract: The present invention provides self-contained systems for performing an assay for determining a chemical state, the system including a stationary cartridge for performing the assay therein, at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with said sample to report a result of the assay, wherein the at least one reagent, the sample and the at least one reporter functionality are contained within the cartridge.Type: ApplicationFiled: June 18, 2018Publication date: October 18, 2018Inventors: Harvey Lee KASDAN, Julien MEISSONNIER, Yoav ZUTA, Micha ROSEN, Yael HIMMEL, Yehoshua BRODER, Bruce DAVIS, Bruce GOLDMAN, Boaz GIRON, Zion BOTESAZAN, Ellezer BLASBERG, Ilan SEMMEL, Jacques ASCHKENASY
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Publication number: 20180231532Abstract: The present invention provides kits, apparatus and methods for determining a biological condition in a mammalian subject, the method includes incubating a specimen from a patient with at least one composition in a kit for a predetermined period of time to form at least one reaction product, when the subject has said biological condition, and receiving an indication of the at least one reaction product responsive to at least one reporter element in the kit thereby providing the indication of the biological condition in the subject.Type: ApplicationFiled: April 10, 2018Publication date: August 16, 2018Inventors: Harvey Lee Kasdan, Julien Meissonnier, Yoav Zuta, Bruce Davis, Micha Rosen, Yael Himmel, Yehoshua Broder
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Patent number: 10024855Abstract: The present invention provides self-contained systems for performing an assay for determining a chemical state, the system including a stationary cartridge for performing the assay therein, at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with said sample to report a result of the assay, wherein the at least one reagent, the sample and the at least one reporter functionality are contained within the cartridge.Type: GrantFiled: August 7, 2017Date of Patent: July 17, 2018Assignee: LEUKODX LTD.Inventors: Harvey Lee Kasdan, Julien Meissonnier, Yoav Zuta, Micha Rosen, Yael Himmel, Yehoshua Broder, Bruce Davis, Bruce Goldman, Boaz Giron, Zion Botesazan, Ellezer Blasberg, Ilan Semmel, Jacques Aschkenasy
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Patent number: 9989523Abstract: The present invention provides kits, apparatus and methods for determining a biological condition in a mammalian subject, the method includes incubating a specimen from a patient with at least one composition in a kit for a predetermined period of time to form at least one reaction product, when the subject has said biological condition, and receiving an indication of the at least one reaction product responsive to at least one reporter element in the kit thereby providing the indication of the biological condition in the subject.Type: GrantFiled: November 16, 2015Date of Patent: June 5, 2018Assignee: LEUKODX LTD.Inventors: Harvey Lee Kasdan, Julien Meissonnier, Yoav Zuta, Bruce Davis, Micha Rosen, Yael Himmel, Yehoshua Broder
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Publication number: 20170370914Abstract: The present invention provides self-contained systems, apparatus and methods for determining a chemical state, the system includes a stationary cartridge for performing the assay therein, the cartridge adapted to house at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with the sample to report a result of the assay, a mechanical controller including a first urging means adapted to apply a force externally onto the cartridge to release the at least one reagent; and at least one second urging means adapted to apply a removable force to induce fluidic movement in a first direction in the cartridge and upon removal of the force causing fluidic movement in an opposite direction to the first direction, an optical reader adapted to detect the reaction and a processor adapted to receive data from the optical reader and to process the data to determine said chemical state.Type: ApplicationFiled: July 11, 2017Publication date: December 28, 2017Inventors: Harvey Lee Kasdan, Julien Meissonnier, Yoav Zuta, Micha Rosen, Yael Himmel, Yehoshua Broder, Bruce Davis, Bruce Goldman, Boaz Giron, Zion Botesazan, Ellezer Blasberg, Ilan Semmel, Jacques Aschkenasy
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Publication number: 20170350888Abstract: The present invention provides self-contained systems for performing an assay for determining a chemical state, the system including a stationary cartridge for performing the assay therein, at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with said sample to report a result of the assay, wherein the at least one reagent, the sample and the at least one reporter functionality are contained within the cartridge.Type: ApplicationFiled: August 7, 2017Publication date: December 7, 2017Inventors: Harvey Lee KASDAN, Julien MEISSONNIER, Yoav ZUTA, Micha ROSEN, Yael HIMMEL, Yehoshua BRODER, Bruce DAVIS, Bruce GOLDMAN, Boaz GIRON, Zion BOTESAZAN, Ellezer BLASBERG, Ilan SEMMEL, Jacques ASCHKENASY
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Patent number: 9759722Abstract: The present invention provides self-contained systems for performing an assay for determining a chemical state, the system including a stationary cartridge for performing the assay therein, at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with said sample to report a result of the assay, wherein the at least one reagent, the sample and the at least one reporter functionality are contained within the cartridge.Type: GrantFiled: December 17, 2013Date of Patent: September 12, 2017Assignee: LEUKODX LTD.Inventors: Harvey Lee Kasdan, Julien Meissonnier, Yoav Zuta, Micha Rosen, Yael Himmel, Yehoshua Broder, Bruce Davis, Bruce Goldman, Boaz Giron, Zion Botesazan, Ellezer Blasberg, Ilan Semmel, Jacques Aschkenasy
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Patent number: 9746462Abstract: The present invention provides self-contained systems, apparatus and methods for determining a chemical state, the system includes a stationary cartridge for performing the assay therein, the cartridge adapted to house at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with the sample to report a result of the assay, a mechanical controller including a first urging means adapted to apply a force externally onto the cartridge to release the at least one reagent; and at least one second urging means adapted to apply a removable force to induce fluidic movement in a first direction in the cartridge and upon removal of the force causing fluidic movement in an opposite direction to the first direction, an optical reader adapted to detect the reaction and a processor adapted to receive data from the optical reader and to process the data to determine said chemical state.Type: GrantFiled: December 17, 2013Date of Patent: August 29, 2017Assignee: Leukodx Ltd.Inventors: Harvey Lee Kasdan, Julien Meissonnier, Yoav Zuta, Micha Rosen, Yael Himmel, Yehoshua Broder, Bruce Davis, Bruce Goldman, Boaz Giron, Zion Botesazan, Ellezer Blasberg, Ilan Semmel, Jacques Aschkenasy
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Publication number: 20160146793Abstract: The present invention provides kits, apparatus and methods for determining a biological condition in a mammalian subject, the method includes incubating a specimen from a patient with at least one composition in a kit for a predetermined period of time to form at least one reaction product, when the subject has said biological condition, and receiving an indication of the at least one reaction product responsive to at least one reporter element in the kit thereby providing the indication of the biological condition in the subject.Type: ApplicationFiled: November 16, 2015Publication date: May 26, 2016Inventors: Harvey Lee Kasdan, Julien Meissonnier, Yoav Zuta, Bruce Davis, Micha Rosen, Yael Himmel, Yehoshua Broder
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Patent number: 9259389Abstract: The present invention concerns a pharmaceutical formulation intended for oral administration containing a synthetic oligosaccharides containing one to 18 monosaccharide units and having a therapeutical activity or a pharmaceutically acceptable additions salt or solvate thereof wherein the formulation contains: a) the synthetic oligosaccharide (A) in an amount of up to 5% by weight of the total weight of the formulation, advantageously up to 1% by weight of the total weight of the formulation, b), a lipophilic phase (B) consisting of triglyceride of fatty acids in an amount of 50 to 80% by weight of the total weight of the formulation, advantageously of 50 to 70% by weight of the total weight of the formulation, c) at least one lipophilic surfactant (C) with HLB below 7 consisting of partial esters of polyol and fatty acids in an amount of 10 to 30% by weight of the total weight of the formulation, advantageously of 15 to 30% by weight of the total weight of the formulation, d) at least one hydrophilic surfactType: GrantFiled: December 17, 2010Date of Patent: February 16, 2016Assignees: ENDOTIS PHARMA, CATALENT FRANCE BEINHEIM SAInventors: Julien Meissonnier, Nathalie Sicre, Guillaume Sabate, Guy Dubreucq, Vanessa Nancy-Portebois, Maurice Petitou
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Patent number: 9207239Abstract: The present invention provides kits, apparatus and methods for determining a biological condition in a mammalian subject, the method includes incubating a specimen from a patient with at least one composition in a kit for a predetermined period of time to form at least one reaction product, when the subject has said biological condition, and receiving an indication of the at least one reaction product responsive to at least one reporter element in the kit thereby providing the indication of the biological condition in the subject.Type: GrantFiled: December 16, 2014Date of Patent: December 8, 2015Assignee: LEUKODX LTD.Inventors: Harvey Lee Kasdan, Julien Meissonnier, Yoav Zuta, Bruce Davis, Micha Rosen, Yael Himmel, Yehoshua Broder